Lung Function Laboratories

The clinical service is complemented by lung function laboratories, which are equipped to undertake a wide range of tests in patients of all ages, including spirometry and lung volume measurements, as well as assessment of airway resistance, diffusion capacity, and blood gases. Progressive exercise testing is used to evaluate patients with breathlessness. Bronchial provocation tests, and exhaled nitric oxide measurements for the diagnosis and management of asthma, are used extensively. Special techniques have been developed to make these tests available for young children. A special laboratory undertakes sophisticated lung function tests in infants.

Lung Transplant Service
In cooperation with the Department of Thoracic Surgery, the Institute screens and evaluates patients who are candidates for lung transplant surgery. Postoperative management and long term follow up are provided by a physician-nurse team specialized in the management of lung transplant patients.

Laboratory for Lung & Molecular Biology
A team of physicians and scientists perform molecular, cellular, and animal studies to investigate mechanisms of lung diseases, including lung fibrosis and asthma, with the long term goal of improving patient care.

Graded Cardiopulmonary Exercise Testing (CPET)
CPET performed in the Pulmonary Function Testing Laboratory in Hadassah Ein-Kerem, serves to evaluate maximal exercise capacity in health and disease, and investigate the pathophysiological mechanisms that limit exercise capacity. Measurements are obtained during performance of incremental effort (cycling) and consist of breath-by-breath oxygen consumption, CO2 output and ventilation, alongside ECG monitoring.

These data are plotted against work rate that increases gradually, to the highest tolerated level. This method attempts to detect subtle lung disease such as pulmonary hypertension, when the results of routine medical tests performed at rest are within normal limits. Additionally, it allows the determination of the relative contribution of each of the co-existing cardiac and pulmonary disease, to exercise limitation in a particular case.