Clinical Activity

The medical team deals with all aspects of general endocrinology, endocrine tumors and diabetes. Outpatient endocrinology and adult diabetes clinics are located at the Hadassah Ein Kerem Hospital. Close cooperation exists between the department of endocrinology and oncology, otolaryngology, neurosurgery, general surgery and transplantation, bariatric surgery, nuclear medicine, radiology, nephrology, gastroenterology and gynecology departments. There is also close cooperation between our medical team and pediatric endocrinologists, endocrinologists and diabetes specialists in the Jerusalem area HMOs, including weekly consultation services.

Endocrine day care, within the framework of internal medicine day care, carries out dynamic endocrine tests including glucose tolerance testing, water deprivation testing, challenge tests, and insulin-induced hypoglycemia to evaluate pituitary hormones reserve. All tests are performed by a skilled nursing staff under the supervision of a senior endocrinologist.

Routine and complex endocrine laboratory tests are carried out in the Hadassah Hospital central laboratories using advanced technology for hormone testing, their intermediate products, antibodies and other endocrine tests. Special tests such as glucagon, PP, VIP, chromogranin and bone turnover markers are also conducted. Genetic testing of known genetic defects and exome sequencing is performed as part of genetic counseling in the Department of Genetics.

The clinical activities of the Department of Endocrinology, Diabetes and Metabolism include all aspects of general endocrinology:

- Prof. Gil Leibovitz, Director of the Diabetes Unit, Dr. Ofri Mosenzon and Dr. Avivit Cahn, together with a multidisciplinary team which includes a diabetes nurse and a dietitian, treat patients with type 1 and 2 diabetes, using advanced technologies which include training patients to use insulin pumps and continuous glucose monitoring devices.

- Dr. Simona Glasberg, Director of the Unit for Neuroendocrine tumors (NET), together with Prof. David Gross, former Director of the Unit, Dr. Kira Olenikov, and a multidisciplinary team treat benign and malignant endocrine tumors, including carcinoid and pancreatic islet cell tumors, pheochromocytomas, medullary thyroid carcinomas and adrenal carcinomas. In collaboration with the Department of Nuclear Medicine, NET patients receive a unique treatment (PRTT). The Center for the Treatment of Neuroendocrine Tumors at Hadassah was recently recognized as a center of excellence by the European Neuroendocrine Tumor Society (ENET). This is the first center of excellence for NET in Israel.

- Prof. Rivka Dresner-Pollak is the Director of the osteoporosis, mineral and bone metabolism diseases service, which includes the management of patients with hyperparathyroidism, hypoparathyroidism, hypophosphatemic disorders, primary osteoporosis and secondary osteoporosis due to excess steroids, treatments for breast and prostate cancer, Paget's disease and osteomalacia.

- Dr. Rena Pollack is in charge of the thyroid clinic and manages malignant and benign thyroid diseases such as under and over activity of the thyroid gland (hypothyroidism, hyperthyroidism, and Graves' disease) as well as thyroid cancers. In collaboration with Dr. Shai Kehat-Ophir from the Department of Ophthalmology, she treats patients with thyroid eye disease. A clinic was recently opened under Dr. Pollack's direction in the innovative field of endocrine effects and disorders in oncology patients treated with novel immunotherapies.

Endocrine Testing

Dynamic tests
including water deprivation, glucose tolerance, growth hormone (GH) suppression, and ACTH stimulation for the diagnosis of Addison’s disease and congenital adrenal hyperplasiasa, saline infusion for primary hyperaldosteronism are performed at the Internal Medicine Day Care (02-6777577).

Bone density by DXA: performed at Hadassah Mount Scopus Osteoporosis Center (02-5845099, 02-5845100).

Special blood and urine assays: including ionized calcium, chromogranin A, biochemical markers of bone turnover: CTX and osteocalcin, gastrointestinal hormones such as VIP and glucagon are performed at the Hadassah Central Laboratories.

Genetic testing forthe diagnosis of genetic endocrine diseases such as MEN1, MEN2, CAH, FHH, Turner’s and syndrome is conducted at the Department of Genetics and Metabolic Diseases including exome sequencing.

Radioactive isotope-based studies and treatments including thyroid and parathyroid mapping, radioactive iodine treatments for benign and malignant thyroid diseases, diagnostic mapping and treatments for neuroendocrine tumors are performed at the Department of Nuclear Medicine in collaboration with the Oncology Department.

Adrenal veins sampling for the diagnosis of primary hyperaldosteronism and inferior petrosal sinus sampling (IPSS) for the diagnosis of Cushing’s disease are performed at the Radiology Department.