ξψλζ ψτεΰι αιϊ ηεμιν δγρδξψλζ ψτεΰι αιϊ ηεμιν δγρδ
φεψ χωψ μχδιμδ δψτεΰιϊ ΰεγεϊ δγρδ γσ δαιϊ 
γσ ψΰωι > ψωιξϊ ψετΰιν, ψετΰι ωιπιιν, τριλεμεβιν εηεχψιν

τψετ' ψεϊ βαιζεο


τψετ' ψεϊ βαιζεο

 

πειψεμεβιδ πιρειιϊ

δξημχδ μπειψεμεβιδ

αιδ"η ςιο-λψν

 

ϊΰψικ μιγδ: 10.9.53 αεΰπερ ΰιιψρ, ΰψβπθιπδ.

ΰζψηεϊ: ιωψΰμιϊ

ξφα ξωτηϊι: πωεΰδ +  4

 

μιξεγιν επιριεο ξχφεςι

 

74-1971 - B.Sc αλιξιδ αΰεπιαψριθδ δςαψιϊ, ιψεωμιν.

76-1974 - ωψεϊ φαΰι αφδ"μ.

78-1976 - M.Sc. αξημχδ μαιετιριχδ αξλεο ειφξο, ψηεαεϊ.

84-1979 -  Ph.D. δξημχδ μαιεμεβιδ ξεμχεμψιϊ αΰεπιαψριθδ δςαψιϊ, ιψεωμιν.

88-1985 - τερθ γεχθεψθ αξημχδ μπειψεμεβιδ, αΰεπιαψριθϊ χμιτεπιδ αρο τψπριρχε. αξςαγϊε ωμ ρθΰπμι τψεζιπψ.

1988 εςγ διεν - δξημχδ μπειψεμεβιϊ πιρειιϊ, δγρδ ςιο λψν, ιψεωμιν.

1990 - ξψφδ αΰεπιαψριθδ δςαψιϊ αιψεωμιν.

1994 (ιπεΰψ – ρτθξαψ)  - τψετρεψ ΰεψη αξημχδ μπειψεμεβιδ αΰεπιαψριθϊ χμιτεψπιδ αρο τψπριρχε.

1996 – ξψφδ αλιψδ αΰεπιαψριθδ δςαψιϊ.

2002 – τψετρεψ αΰεπιαψριθδ δςαψιϊ.

 

ξμβεϊ εξςπχιν

 

1985 - δξμβδ μτερθ γεχθεψπθιν ξξλεο ειφξο.

1992 – ξμβϊ δφθιπεϊ αξηχψ ξδΰεπιαψριθδ δςαψιϊ ξδξημχδ μμιξεγι ψτεΰδ.

 

ψωιξϊ τψρεξιν ξηξω δωπιν δΰηψεπιεϊ

 

Garty H., Eisenbach M., Shuldman R*., Caplan S.R. : Light induced pH changes in sub-bacterial particles of Halobacterium Halobium. Effects of ionophors. Biochim. Biophys. Acta  545: 363-375, 1979.

 

*Previous name of R Gabizon

 

Gabizon R., Yetinzon T., Schuldiner S. Photoinactivation of the biogenic amine transporter in chromaffin granules from bovine adrenal medulla. J. Biol. Chem. 257: 15145-15150, 1982.

 

Schuldiner S., Gabizon R., Maron R., Suchi R., Stern Y., The amine transporter of bovine chromaffin granules. Ann. NY Acad. Sci.260: 268-273, 1985.

 

Gabizon R., Schuldiner S.  The  amine transporter of bovine chromaffin granules: Partial purification. J. Biol. Chem. 260:3001-3005, 1985.

 

Schuldiner S., Gabizon R., Stern Y., Suchi R. The  amine transporter of bovine chromaffin granules: Photolabeling and partial purification. Ann. NY Acad. Sci. 493: 189-193, 1987.     

 

Prusiner S.B., Gabizon R., McKinley M.P. On the biology of prions. Acta Neuropathol. (Berl.) 72: 299-314, 1987.

 

Gabizon R., McKinley M.P., Prusiner S.B. Purified prion proteins and scrapie infectivity copartition into liposomes. Proc. Natl.Acad. Sci. USA 84: 4017-4021. 1987.

 

Gabizon R., McKinley M.P., Groth D.F., Kenaga L., Prusiner S.B. Properties of scrapie prion liposomes. J. Biol. Chem. 263: 4950-4955, 1988.

 

Bellinger-Kawahara C.G., Kempner E., Groth D., Gabizon R.,Prusiner S.B. Scrapie prion liposomes and rods exhibit target sizes of 55000 Da. Virology 164: 537-541. 1988.

 

Gabizon R., Groth D.F., McKinley M.P., Prusiner S.B..Immunoaffinity purification and neutralization of scrapie prion infectivity. Proc. Natl. Acad. Sci. USA 85: 6617-6621, 1988.

 

Gabizon R., Prusiner S.B. Prion liposomes. Bioch. J. 266: 1-4,1990.

 

Hsiao K., Meiner Z., Kahana E., Cass C., Kahana I., Avrahami D., Scarlato G., Abramsky O., Prusiner S. B., and Gabizon R. Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease. N. Engl. J. Med. 324, 1091-1097. 1991.

 

Meiner Z., Gabizon R., Kahana E., Creutzfeldt- Jakob-Disease :Etiology and Epidemiology. Harefuah (Hebrew) 120; 19-22, 1991.

 

Meiner Z., Halimi M., Polakiewics R.D., Prusiner S.B. and Gabizon R. Presence of prion protein in peripheral tissues of Libyan Jews with Creutzfeldt-Jakob disease. Neurology; 42: 1355-1360. 1992.

 

Prusiner S.B., Groth D., Serban A., Sthal N., and Gabizon R. Attempts to restore scrapie prion infectivity after exposure to protein denaturants. Proc. Natl. Acad. Sci. USA 90: 2793-2797,1993.

 

Goldhammer Y.,Gabizon R., Meiner Z., Sadeh M. An Israeli family with Gerstmann-Staussler-Scheinker disease manifesting the codon102 mutation in the prion protein gene.  Neurology; 43: 2718-2719, 1993.

 

Gabizon R., Meiner Z., Halimi M., Ben Sasson S.A. Heparin- like molecules bind differentially to prion-proteins and change their intracellular metabolic fate. J. Cell. Physiol. 157; 319-325,  1993.

 

Gabizon R., Rosenman H., Meiner Z., Kahana I., Kahana E., Shugart Y., Ott J., Prusiner S.B. Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt -Jakob Disease. Am.J.Hum.Genet. 53; 828-835, 1993.

 

Gabizon R., Rosenman H., Meiner Z., Kahana I., Kahana E., Shugart Y., Ott J., Prusiner S.B. Mutation in codon 200 and polymorphism in codon 129 of thep rion protein gene in Libyan Jews with CJD. Phil. Trans. R. Soc. Lond. B 34: 385-390, 1994. 

 

Gabizon R., Halimi M., and Meiner Z.. Genetics and biochemistry of Creutzfeldt-Jakob disease in Lybian Jews. Biomedicine &Pharmacotherapy , 48; 385-390, 1994. 

 

Friedman G., Gabizon R., Shapira A., Castel., Wertman E., Matsa D., Rosenmman H., Schurr D., Wirtheim E., Friedlander Y., Ben Yehuda A. Association of apolipoprotein E4 alleles with Alzeheimer's disease, but not with Down's syndrome or Creutzfeldt-Jakob disease among Israeli Jews. Alzheimer's Research 1; 45-48, 1995.  ( NOT IN THE LISTS 6)

 

Spudich S., Mastrianni J.A., Wrensch M., Gabizon R., Kahana I.,Rosenmman H., Kahana E., Prusiner S.B. Complete penetrance of Creutzfeldt -Jakob disease in Libyan Jews carrying the E200K mutation in the prion protein. Molecular Medicine 6; 607-613, 1995. (5.032; 19/129;21)

 

Telling G.C., Scott M., Mastriani J., Gabizon R., Torchia M., Cohen F.E., DeArmond S.J., and Prusiner S.B. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. . Cell; 83, 79-90. 1995. (37.297; 1/129; 187)

 

Kaneko K., Peretz, D., Pan, Keh-Ming., Blochberger, T.C., Wille, H., Gabizon, R., Griffith, O.H., Cohen F.E., Baldwin, M.A., and Prusiner S.B.  Prion protein (PrP) synthetic peptides induce cellular PrP to aquire properties of the scrapie isoform. Proc.Natl. Acad. Sci USA, 92; 11160-11164, 1995. (9.04; 3/56; 36)

 

Gabizon R., Telling G., Meiner Z., Halimi M., Kahana I., and Prusiner S.B. Insoluble wild type and protease resistant mutant PrP were found in the brains of patients who died of inherited prion disease.  Nature Medicine, 2;  59-64, 1996.  (28.114;  3/250; 25)

 

Ovadia H., Rosenmman H., Halimi M., Ofran I., Shezen E.,and Gabizon R.. Nitric oxide synthase is inhibited and abberantly processed in scrapie infected cells and brains. J. Biol. Chem, 271;  16856-61, 1996. (6.96; 23/ 250; 4)

 

Telling G.N , Parchi P. ,  DeArmond S.J. , Cortelli  P. ,Montagna P., Gabizon R., Mastrianni J., Lugaresi E. , Gambetti B. , Prusiner SP.  Evidence for the conformation of the phatologic isoform of the prion protein enciphering and propagating prion  diversity. Science: 274; 2079-2082, 1996 (24.67; 2/56; 110)

 

Rosenmann H. , Meiner Z., Kahana E., Halimi H., Lenetsky E., Abramsky O.,Gabizon R. Detection of  14-3-3 protein  in the cerebrospinal fluid of genetic CJD. Neurology 49(2); 593-595, 1997. (4.5; 5/107; 7)

 

Rosenmann H. , Halimi H. , Kahana I. , Biran I., and  Gabizon R.    Differential  allelic expression of prp mrna in carriers of the E200K  mutation. Neurology. 49(3); 851-6, 1997. (4.5; 5/107; 5)

 

Gabizon R and Taraboulos A.  Of Mice and (mad) Cows. Trends Genet 13(7); 264-269, 1997. (9.9; 6/90; 5)

 

Meiner Z,  Gabizon R and Prusiner S.B. 1977.    Genetic Creutzfeldt-Jakob disease in Lybian Jews. Medicine (Baltimore) 76(4);  227-237, 1997. ( 4.48; 8/100;5)

 

Rosenmann  H.,  Vardi   J., Finkelstein  Y., and Gabizon R.. Identification in Israel of 2 Jewish CJD patients with a 178 mutation at their PrP gene. Acta Neurol Scan ; 184-187, 1998. (0.902; 64/107;0)

 

Caspi S, Halimi M, Yanai A,  Ben Sasson S, Taraboulos A and Gabizon R The Anti Prion Activity Of Congo Red: Putative Mechanism. J. Biol. Chem  273;  3484-3489, 1998. .(6.96;  23/250/ 6)

 

Keshet G., Ovadia H and Gabizon R. Scrapie infected mice and PrP knockout mice share abnormal  localization and activity of Neuronal Nitric Oxide Synthase. J. Nerochem, 72;  1224-1231, 1999. (4.23;  21/150/ 1)

 

Shaked GM,  Fridlander G,   Meiner Z, Taraboulos A and  Gabizon R. Protease-Resistant And Detergent-Insoluble Prion Protein Is Not Necessarily Associated With Prion Infectivity, J.Biol. Chem 274; 17981-17986, 1999.(6.96;  23/250/ 1)

 

Rosenmann H,  Kahana E,  Korczyn,   Kahana I, Chapman J, and Gabizon R.  Preliminary  Evidence  For  Anticipation  In Genetic E200k Creutzfeld- Jakob - Disease. Neurology.   12; 53, 1328-9, 1999. (4.5; 5/107; 1)

 

Shaked Y, Rosenmann H, Talmor G  and  Gabizon R.  A  C-Terminal Truncated  PrP Isoform Is Present In Mature Sperm.  J. Biol. Chem ,  274; 32153-8, 1999..(6.96;  23/250/ 0)

 

Yanai A, Meiner Z, Gahali I, Gabizon R and Taraboulos A. Subcellular trafficking abnormalities of a prion protein with a disrupted  loop. Febs Lett,  22754; 11-16, 1999. (3.5; 53/250; 0)

 

Simon, E. S., Kahana, E., Chapman, J., Treves, T. A., Gabizon, R., Rosenmann, H., Zilber, N., Korczyn, A. D.  Creutzfeldt-Jakob disease profile in patients homozygous for the PRNP E200K mutation. Ann Neurol, 47; 257-60, 2000. (9.5; 1/107; 0)

 

Keshet I, Bar-Peled O,  Yaffe D, Nudel U, Gabizon R; The Cellular Prion Protein Is A Member Of The Dystroglycan Complex In The Brain. J Neurochem. 2000 Nov;75(5):1889-97.

 

Shaked GM,   Meiner Z,  Taraboulos Z and Gabizon R; Reconstitution of prion infectivity from solubilized protease resistant PrP and non-protein components of prion rods. J. Biol Chem. 2001 Jan 4

 

Rosenmann H, Talmor G, Halimi M, Yanai A, Gabizon R, Meiner Z. . Prion Protein With An  E200k Mutation Displays Properties Similar To Those Of The   Cellular  Isoform, PrPc . Journal of Neurochemistry, 2001 Mar 15;76(6):1654-1662.

 

Shaked Y,  Rosenmann H, Hijazi N,  Halimi M and Gabizon R. Copper Binding To The PrP Isoforms:  A Putative Marker Of Their  Conformation And Function. Journal of Virology. 2001 Sep; 75(17):7872-4.

 

Shaked GM, Shaked Y,  Kariv Z, Halimi M,   Avraham Iand   Gabizon R.  A protease resistant PrP isoform is present in urine of animals and humans affected with prion diseases. J Biol Chem. 2001 Aug 24;276(34):31479-82.

 

Yuval Shaked , Roni Engelstein, Ruth Gabizon. The Binding Of Prion Proteins     To Serum Components Is Affected By    Detergent Extraction Conditions . 2002;  J Neurochem.  Jul;82(1):1-5.

 

Gideon Shaked,  Roni Engelstein,  Michele Halimi,  Inbal Avraham Hanna Rosenmann Ruth Gabizon. Valproic Acid, An Anti Epileptic Drug,  Modulates The Accumulation of the Prion Proteins. 2002;  Ann Neurol Oct;52(4):416-20.

 

Shaked Y, Hijazi N, Gabizon R. Doppel and PrP(C) do not share the same membrane microenvironment.2002; FEBS Lett  Oct 23;530(1-3):85-8.

 

Tzaban S, Friedlander G, Schonberger O, Horonchik L, Yedidia Y, Shaked G, Gabizon R, Taraboulos A. Protease-sensitive scrapie prion protein in aggregates of heterogeneous sizes. 2002; Biochemistry 2002 Oct 22;41(42):12868-75

 

Shaked GM, Engelstein R, Avraham I, Kahana E, Gabizon R. Dimethyl sulfoxide delays PrP(sc) accumulation and disease symptoms in prion-infected hamsters.  Brain Res. 2003 Sep 5;983(1-2):137-43.


Hijazi N, Shaked Y, Rosenmann H, Ben-Hur T, Gabizon  R. Copper binding to PrPC may inhibit prion disease propagation.Brain Res. 2003 Dec 12; 993(1-2): 192-200


 Schonberger O, Horonchik L, Gabizon R, Papy-Garcia D, Barritault D, Taraboulos A.Novel heparan mimetics potently inhibit the scrapie prion protein and its endocytosis. Biochem Biophys Res Commun. 2003 Dec 12; 312(2): 473-9.

 

Hijazi N, Kariv-Inbal Z, Gasset M, Gabizon R. PrPSc incorporation to cells requires endogenous GAGs expression. J Biol Chem. 2005 Jan 24.

 

Engelstein R, Grigoriadis N, Greig NH, Ovadia H, Gabizon R. Inhibition of P53-related apoptosis had no effect on PrP(Sc) accumulation and prion disease incubation time. Neurobiol Dis. 2005 Mar;18(2):282-5.

 

Kariv-Inbal Z, Halimi M, Dayan Y, Engelstein R, Gabizon R. Characterization of light chain immunoglobulin in urine from animals and humans infected with prion diseases. J Neuroimmunol. 2005 May;162(1-2):12-8.

 

 

τψχιν αρτψιν

 

Garty H., Eisenbach M., Shuldman R*., Caplan S.R.: Effects of ionophores on light -induced pH changes in sub-bacterial particles of Halobacterium Halobium. In : Energetics and structure of halophilic Microorganisms, Caplan S.R., Ginzburg M (eds). Elsvier/North Holland and Biomed Res., pp. 261-267, 1978.

Previous name of R Gabizon

 

Gabizon R., McKinley M.P., Prusiner S.B. Properties of scrapie prion liposomes and amyloid rods. In: Novel infectious agents and the central nervous system. Ciba Foundation Symposium 135, Bock, G, Marsh J., (eds). John Wiley and Sons, Chichester, UK pp 182-196, 1988.

 

Gabizon R., McKinley M.P., Prusiner S.B. Incorporation of scrapie prion protein and infectivity into Phospholipid vesicles. In: II International symposium on unconventional viruses of the central nervous system, Court L.A. Paris , 1989.

 

Gabizon R., McKinley M.P., Groth D.F., Prusiner S.B. Prions causing neurodegenerative diseases- Imunoaffinity purification and neutralization of scrapie infectivity. In: Biomedical advances in aging. Proceedings of the VIIIth International Washington spring symposium. Plenum Press, New York, 1990.

 

Gabizon R., McKinley M.P., Groth D.F., Westaway D., DeArmond S.J., Carlson G.A., Prusiner S.B.  Imunoaffinity purification and neutralization of scrapie prions. In: Proceedings of the first International Conference on Alzheimer's Disease and Related Disorders, Las Vegas 1990.

 

Prusiner, S.B., Carlson G.A., DeArmond S.J., Gabizon R., Hsiao K., Scott M., Stahl N., Westaway D. Transmissible and genetic prion diseases of humans and animals. In: The Molecular and Genetic Basis of Neurological Disease. 9R. Rosenberg, S. Prusiner, S. DiMauro, R. Bachi, L. Kunkel, eds) Butterworth Pub. Stoneham, Ma. 1992.

 

Gabizon R., Kahana R., Hsiao K., Prusiner S.B., Meiner Z. Inherited prion disease in Libyan Jews. In: Prion Diseases in Human and Animals. Prusiner S.B., Collingo J., Ponell J., Anderton B., (eds). Ellis Horwood, London, pp. 168-179. 1992.

 

Meiner Z., Halimi M., Polakiewics R.D., Prusiner S.B. and Gabizon R. Detection of the prion protein in peripheral tissues of Libyan Jews with Creutzfeldt-Jakob disease. In "Advances in the Biosciences". 87: 105-111. 1993.

 

Gabizon R, Telling G., Meiner Z., Halimi M., Kahana I., and Prusiner S.B.  Altered properties of prion proteins in Creutzfeldt-Jakob disease patients heterozygous for the E200K mutation.In Transmissible subacute spongiform encephalopathies: Prion Diseases. Edited by Louis Court and Betty Dodet; Elsevier. 1996

 

Gabizon R , Glenn Telling, Zeev Meiner, Michele Halimi, Irit Kahana and Stanley B. Prusiner.  Wild Type And Mutant Prion Protein Properties In Creutzfeldt Jakob Disease Patients Heterozygous For The E200k Mutation. Nato meeting on TSE diseases, Sicily, Italy. 1997.

 

Gambetti P, Petersen RS, Parchi P, Chen SG, Capellari S, Goldfarb L, Gabizon R, Montana P, Lugaresi E, Piccardo P, and Getti B.  Inherited Prion Diseases; in Prion Biology and Disease, Cold Spring Harbor laboratory press. 1999. 

 

ϊχφιψιν παηψιν

 

Schuldiner S., Gabizon R. The amine transporter from bovine chromaffin granules . J. Neurochem (Suppl.) 41: 953a, 1983.

 

Tamir H., Liu K.P., Hsuing S.H., Gabizon R., Gershon M.D. Photoaffinity labeling of 45 kd and 56 kd forms of the serotonin binding protein (SBP): Evidence that 45 kd SBP is stored in

synaptic vesicles. Society of Neuroscience, 1984.

 

Gabizon R., McKinley M.P., Prusiner S.B. Incorporation of scrapie prion protein and infectivity into Phospholipid vesicles.  II Symposium International Sur Les Virus Non Conventionnels Du Systeme Nerveus Central. Paris, Dec 2-6, 1986.

 

Gabizon R., McKinley M.P., Prusiner S.B. reconstitution of the scrapie prion protein into liposomes. J. Cell Biol.103; 337a, 1986.

 

Gabizon R., Gilles K., McKinley M.P., Prusiner S.B. Reversible morphological changes of infectious scrapie prions. Clin. Res. 35: 614A, 1987.

 

Gabizon R., McKinley M.P., Groth D.F., Prusiner S.B. Properties of scrapie prion proteins in liposomes and amyloid rods.  Ciba Foundation Symposium No. 135 Unconventional Viruses and the CNS, June 29-July 2, 1987.

 

Gabizon R., McKinley M.P., Groth D.F., Kenaga L., Prusiner S.B. Properties of scrapie prion proteins in detergent -lipid –protein complexes. Ann. Neurol. 22:157,1987.

 

 

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