Former Head
Department of Obstetric and Gynecology
Hadassah University Hospital
Mount Scopus Jerusalem
E-mail: arielm@md2.huji.ac.il
Fax. 972-2-5814210
Curriculum
Born in Jerusalem, (Hadassah Hospital, Mt. Scopus) in 1944
1972 , M.D. degree, Hadassah Hebrew University Medical School, Jerusalem
Specialist in Obstetrics and Gynecology, since 1980.
Specialization at Sha’are Zedek Hospital, Hadassah Mount Scopus Hospital and Baylor College of Medicine, Houston, Texas, USA
Academic clinical interests: Fetal maternal medicine (perinatology), Menopause.
Research interests
Fetal maternal medicine, plasminogen activation
Awards
Hebrew University, Hadassah Medical School award for outstanding M.D. thesis
The Bat-Sheva De Rothschild research grant for outstanding young researchers, “Halperin” Hebrew University Hadassah Medical School award for best clinical teacher.
Community services
Member of Hadassah Hospitals, Medical Committee. Member of the “Alyn Hospital”, Pediatric and adolescent rehabilitation center, directors committee.
Deputy Director, Hadassah University Hospital, Mount Scopus
List of Publications
Effect of Amnio Acids on the Activities of Enzymes of Glycolysis and Glycogen metabolism in Rat Adipose Tissue in vitro. M. D. THESIS - January 1972 (Received Medical School Award for outstanding doctoral thesis).
1) Abu-Dallo, K.A.I., Milwidsky A, Borman, J. B.: Combined left ventricular aneurysmectomy and infarctectomy in a 73 year old male. Geriatrics 28: 140-143, 1973.
2. Weiss, D., Kamer, R., Aboulafia, Y. and Milwidsky A.: Schistosomiasis of the cervix. Harefuah (in Hebrew) 88: 15-17, 1975.
3. Borman, J. B., Simcha, A., Milwidsky, A, Davidson, J. T., Tzivoni, D. and Gotsman, M.S.: Long term results of the valve replacement in children suffering from rheumatic heart disease. Israel J. Med. Sci. ll: 144-151, 1975.
4. Wajntraub, G., Milwidsky, A. and Weiss, D.: Prevention of premature delivery in a unicornuate uterus by cervical cerclage. Acta Obstet. Gynecol. Scand. 54: 497-498, 1975.
5. Milwidsky, A., Aboulafia, Y. and Weiss, D. Intestinal obstruction in pregnancy. Harefuah (In Hebrew) 89: 249-250, 1975.
6. Sadovsky, E., Aboulafia, Y., Milwidsky A, Weinstein, D and Polishuk, W. Z.: Pre-eclampsia and fetal well being. Israel J. Med. Sci. 12: 528-533, 1976.
7. Weiss, D., Aboulafia, Y. and Milwidsky, A.: Ectopic pregnancy and the pill. Lancet 2: 1094 - 1095, 1976 (Letter).
8. Milwidsky,A., Adoni,A., Palti, Z., Stark, M. and Segal, S.: The significance of human chorionic gonadotropins in blood serum for the early diagnosis of ectopic pregnancy. Acta Obstet. Gynecol. Scand 56: 19-21, 1977.
9. Herishanu, Y. and Milwidsky, A.: Trigeminal neuralgia induced by Nitrofurantoin treatment. J. Neurol. 216: 77-78, 1977.
10.Sadovsky, E. Weinstein, D., Aboulafia, Y., Milwidsky, A. and Polishuk, W. Z.: Decreased fetal movements associated with umbilical cord complications. Israel J. Med. Sci. 13: 295-298, 1977.
11. Milwidsky. A.. Adoni. A., Segal, S. and Palti,Z.: H. C. G. and progesterone in ectopic pregnancy. Obstet. Gynecol. 50: 145-147, 1977.
12. Brufman. G.. Biran, S., Milwidsky. A. and Behar, A.J.: Solitary lung involvement from clear cell carcinoma of endometrium. Int. Surgery 63: 86-88 1978.
13. Milwidsky, A.. Adoni, A., Miodovnik, M., Segal, S. and Palti, Z.: Human chorionic gonadotropin (B subunit) in the early diagnosis of ectopic pregnancy. Obstet. Gynecol 51: 725-727, 1978.
14. Stark, N. Adoni, A. Milwidsky, A., Gilon, G. and Palti Z.: Can estrogen be useful for treatment of vaginal relaxation in elderly women? Am. J. Obstet. Gynecol. 131: 585-586 1978.
15. Stanley, R. L., Milwidsky, A., and Besch, P. K.: Evidence for an androgen binding component in the cytosol of the human term placenta. Am. J. Obstet. Gynecol. 136: 1003-1005, 1980.
16. Milwidksy. A., Stanley, R.L., Besch, P.K. and Kaufman, R.H.: Receptor-like binding proteins for testosterone and progesterone in the human ovary. Am. J. Obstet. Gynecol. 138: 93-98, 1980.
17. Milwidsky, A., Palti. Z. and Gutman. A.: Glycogen metabolism of the human endometrium. J. Clin. Endocrinol. Metab. 51: 765-770, 1980.
18. Adoni, A., Palti, z., Milwidsky, A. and Dolberg, M.: The incidence of intrauterine adhesions following spontaneous abortions. Int. J. Fertil. 27 (2): 117-118, 1982.
19. Milwidsky, A., Beller, U.. Palti. Z. and Mayer, M.: Protease and protease inhibitory activity in pregnant and post partum in voluting uterus. Am. J. Obstet. Gynecol. 143: 906-911 1982.
20. Milwidsky, A.. Stanley, R.L., Besch, P.K. and Kaufman. R.H.: Evidence for a direct action of Dnazol on the human ovary. Acta Obstet. Gynecol. Scand. 62: 187-190, 1983.
21. Milwidsky. A. and Gutman, A.: Glycogen metabolism of the human myometrium and fibroids possible hormonal control. Gynec. Obstet. Invest. 15: 147-152, 1983.
22. Hurwitz. A., Milwidsky, A., Yagel, S. and Adoni, A.: Early unwinding of torsion of an ovarian cyst as a result of hyperstimulation syndrome. Fertil. Steril. 40: 393-394, 1983.
23. Hochner-Celnikier,D.. Yagel,S., Beller, U. and Milwidsky.A.: Simultaneous pregnancy in each cavity of a double uterus. Int. J. Gynecol. Obstet. 21: 51-53l 1983.
24. Hurwitz, A,, Milwidsky, A., Yarkoni, S. and Palti, Z.: Severe fetal distress combined with hydramnios due to chorioangioma. Acta Obstet. Gynecol. Scand. 62: 633-635, 1983.
25. Hochner-Celnikier, D., Milwidsky. A., Menashe, M., Ariel I. and Palti. Z.: Pelvic abscess with Lippes Loop - an unusual case. J. of Reproductive Med. - 28 (8) 542-545, 1983.
26. Milwidsky. A.. Yagel, S., Chaout, M. and Mayer, M.: Direct effect of glucocorticoids on the spectrophotometric assay of billirubin in amniotic fluid. Clinical Chemistry 30: 677-680, 1984.
27. Hurwitz, A., Adoni, A., Palti, Z. and Milwidsky, A.: Is the conservative management of premature rupture of membranes justified? Int. J. Obstet. Gynecol. 22: 131-1351 1984.
28. Milwidsky, A., Gal, A. and Mayer. M.: Protease activity in fibromyoma and normal human myometrium. Gynecol. Obstet. Invest. 18: 230-233, 1984
29. Hochner-Celnikier,D., Hurwitz, A.. Beller, U.. Milwidsky, A. and Yagel. S.: Uterus didelphys - ultrasound diagnosis in the case of an adnexal mass as a presenting symptom in early pregnancy. Europ. J. Obstet. Gynecol. Reprod. Biol. 16: 339-342 1984.
30. Yagel. S.. Milwidsky. A., Chaout, M.. Palti, Z. and Mayer,M.: Effect of glucocorticoids on the direct spectrophotometric determination of bilirubin in amniotic fluid. IN: “Recent advances in pathosphysiological conditions in pregnancy”, J.G. Shenker, E.T. Rippmann, D. Weinstein. Eds., Excerpta Medica, Amsterdam-Oxford-Princeton, pp. 74-78, 1984.
31. Hurwitz. A.. Adoni, A.. Palti, Z. and Milwidsky, A.: Is conservative management of premature rupture of membranes justified: In: Recent Advances in Pathophysiological Conditions in pregnancy. Excerpta Medica. International Congress Series, 631: pp. 433-436, 1984.
32. Milwidsky, A., Segal.S., Menashe, M., Adoni, A. and Palti, Z.: Corpus luteum function in ectopic pregnancy. Int. J. Fertil., 29: 244-246, 1984.
33. Yagel, S., Milwidsky, A., Palti, Z. and Ornoy, A.: The significance of prenatal diagnosis of hypophoshpatasia. In: current advances in Skeletogenesis. Inductive Biomineralization Bone Feeding Hormones, Congenital and metabolic Bone Disease. Excerpta Medica. International Congress Series, 643: PP. 263-268 1985.
34. Hurwitz, A., Milwidsky. A.. Medina. A. and Yagel, S.: Failure of continuous intravenous heparinization in preventing stroke in a pregnant woman with a prosthetic valve and atrial fibrillation. J. of Reprod. Med. - 30:181, 618-620, 1985.
35.Yagel,S., Palti,Z.. Ornoy. A., Gutman, A., and Milwidsky, A.: The prenatal diagnosis of Hypophosphatasia. Am. J. of Perinatol. -2:3, 261-262, 1985.
36. Hurwitz, A.. Brautbar, C., Milwidsky, A., Vecsei, P., Milewicz, A., Navot, D. and Rosler, A.: Studies on the nature of familial congenital adrenal hyperplasia due to combined 21 - and 11 B- hydroxylase deficiency. J. Clin. Endocrinol. Metab. - 60; 4l 631-638, 1985.
37. Rizel, S., Biran, S., Anteby, S. 0., Brufman, G., Sulkes, A., Milwidsky, A., Weshler, Z. and Fuks, Z.: Combined Modality treatment for stage III ovarian carcinoma. Chemotherapy and Oncology, 3; 237-244, 1985.
38. Milwidsky, A., Hurwitz, A., Eckstein. L.. Mayer. M.. and Gutman, A.: Proteolytic enzymes in human fetal membranes and amniotic fluid - a comparison of normal and premature ruptured membranes. Enzyme 33: 188-196 1985.
39. Adoni, A.. Milwidsky, A. Hurwitz, A. and Palti, Z.: Declining B - HCG levels - an indicator for expectant approach in ectopic pregnancy. Int. J. Fertil. - 21 (1) 40-42 1986.
40. Adoni, A., Milwidsky, A. and Palti, Z.: The role of ultrasound in ovulation induction by gonadotropins. Int. J. Fertil. - 31 (2) 170-174, 1986.
41. Yagel, S.1 Mazar, I.1 Palti, z., Milwidsky, A.: Successful treatment of premature delivery with low doses of BETA~2 mimetic drugs. In: The Intrauterine Life: Management and Therapy. Excerpta Medica, International Congress Series 689, 75-79 1986.
42. Milwidsky. A., Zarura, R., Hurwitz, A.1 Adoni. A., Kahane, I.: Oxytoxin administration during labor and osmotic fragility of new-born cord blood erythrocytes. Journal of Obstetrics and Gynecology. 7 (2) 111-114, 1986.
43. Milwidsky, A., Hurwitz, A., Nubani, N., Palti, Z., Adoni, A., Brautbar, C.: Absence of HLA linkage in familial hypogonadotropic hypogonadism. J. Of Reproductive Med. 32 (2) 96-98 1987.
44. Menashe, M., Finci., Z., Milwidsky, A. and Mayer, M.: Amniotic fluid protease activity, protease inhibitory activity and fetal lung maturity. American Journal of Perinatology, 4 (1), 68-71, 1987.
45. Shalev, O., Rahav, G. and Milwidsky, A.: Reversible bunsulfan induced ovarian failure. EUR. J. Obstet. Gynecol. Reprod. Biol. 26, 239-242, 1987.
46. Milwidsky, A., Finci, Z. and Mayer, M.: Plasminogen activator activity and urokinase inhibitor activity in human amniotic fluid and fetal membranes. Clin. Biochem., 21: 301-306, 1988.
47. Mayer, M., Yedgar, S., Hurwitz, A., Palti, Z., Finci, Z. and Milwidsky, A.: Effect of viscous macromolecules on peritoneal plasminogen activator activity: A potential mechanism for their ability to reduce postoperative adhesion formation. Am. J. Obstet. Gyencol., 159 (4), 957-963, 1988.
48. Younis, J.S., Sadovsky, E., Eldar-Geva, T., Milwidsky, A., and Zeevi, D.: Twin gestation and prophylactic hospitalisation. Int. J. Gynecol. Obstet., 32:325-330, 1990.
49. Eldar-Geva, T., Hurwitz, A., Vecsel, P., Palti, Z., Milwidsky, A. and Rosler, A.: Secondary biosynthetic defects in women with late-onset congenital adrenal hyperplasia. The New England Journal of Medicine, 323(13), 855-863,1990.
50. Milwsidsky, A., Finci-Yeheskel, Z. and Mayer, M.: Stimulation of plasmin activity by Aspirin. Thrombosis and Haemostasis, 65:389-393, 1991.
51. Anteby, E., Milwidsky, A., Goshen, R., Ben-Chetrit, A. and Ron. M.: IUD-Associated abdominopelvic actinomycosis. Harefuah, 121: 150-153, 1991.
52.Anteby, E., Milwidsky, A. and Shalev, O.: Primery fibrinogenolysis complicating second trimester placental separation. Arch. Gynecol. Obstet., 251, 51-53, 1992.
53. Milwidsky, A. Finci-Yeheskel, Z. and Mayer, M.: Direct inhibition of proteases and cervical plasminogen activator by antibiotics. Am. J. Obstet. Gynecol. 166. (2) 606-692 1992
54. Anteby, E., Hurwitz A.. Palti. Z., Amir. G., Yagel. S.. Lavy. Y.. Szold, A., Bar-Ziv, J. and Milwidsky, A.: Gallstones in an ovarian dermoid cyst. The New England Journal of Medicine. 327. 129-130, 1992 (letter).
55. Milwidsky. A., Finci~Yeheskel. Z., Yagel. S. and Mayer. M.: Gonadotropin-Mediated inhibition of proteolytic enzymes produced by human trophoblasts in culture. JCEM. 76:1101 - 1105, 1993.
56. Milwidsky, A., Finci-Yeheskel, Z. and Mayer M.: Direct stimulation of urokinaser plasmin and collagenase by meperidine. A possible mechanism for the ability of meperidine to enhance cervical effacement and dilatation. Am. J. Perinatol. 10:130 - 134, 1993.
57. Ravel A.. Lavy Y. ' Anteby E., Milwidsky A., Yagel S.: Sinusoidal fetal heart pattern following intravascular intrauterine transfusion for severe issoimmune anemia. Isr. J. Obstet. Gynecol. 4(l):38-40. 1993.
58. Hurwitz A., Dushnik M. Solomon H., Ben Shitrit A., Finci-Yeheskell Z., Milwidsky A., Mayer M., Adashi EY., Yagel S.: Cytokine-mediated regulation for rat ovarian function. Interleukin-1 stimulates the accumulation of 92-kD gelatinase. Endocrinology 132:2709~2714,1993.
59. Yagel S.. Geva TE., Solomon H., Shimonovitz S.. Reich R., Finci-Yeheskel Z., Mayer M., Milwidsky A.: High levels of hCG retard first trimester trophoblast invasion in-vitro by decreasing uPA and collagenase activities. JCEM 77, 1506-1511, 1993.
60. Milwidsky A., Finci-Yeheskel Z., Yagel S. and Mayer M.: Gonadotropin~mediated inhibition of proteolytic enzymes produced by human trophoblasts in culture. j. Clin Endoc. 76: 1101-1105, 1993.
61. Hurwitz A., Finci-Yeheskel. Z., Dushnik M., Milwidsky A., Ben Chetrit A., Yagel S., Adashi EY., and Mayer M.: Cytokine-mediated regulation of rat ovarian function: Interleukin-1 inhibits plasminogen activator activity through the induction of plasminogen activator inhibitors (PAI-1). Molec. Cell. Endocrinol. 101:307-314, 1994.
62. Hurvitz, A., Lavy, Y., Finci-Yeheskel , Z. Milwidsky, A., Shimonovitz. S., Yagel, S., Adashi, E. Y., Laufer N. and M. Mayer: Interleukin-1 -mediated stimulation of prostaglandin E production is without effect on plasminogen activator activity in human granulosa lutein cell cultures. J. Clin. Endoc. Metab. 80: 3018-3024,1995
63. Hurwitz A., Finci-Yeheskel Z, Dushnik, M. Milwidsky A., Shimonovitz, S. , Yagel, S., Adashi E.Y. and M. Mayer.: Interleukin- 1 -mediated regulation of plasminogen activator activity in pregnant mare serum gonadotropin-primed rat granulosa cells is independent of prostaglandin production. J. Soc. Gynecol. Invest. 2: 691-700, 1995.
64. Hurwitz A., Finci-Yeheskel Z., Milwidsky A.. S, Yagel. EY Adashi, N. Laufer and M. Mayer in vitro modulation of plasminogen activator activity, prostaglandin E and nitric oxide production by interleukin-1 in pregnant mare serum gonadotropin-primed theca-interstitial cells. Human Reproduction 12: 774-779, 1997.
65. Hochner-Celnickier D., Greenfeld C., Finci-Yeheskel Z., Milwidsky A., Gutman A., Goldman-Wohl D., Yagel S. and M. Mayer.: Tamoxifen exerts estrogen-agonistic effects on proliferation and plasminogen activatior, but not on gelatinase activity, glycogen metabolism and p53 protein expression, in cultures of estrogen-responsive human endometrial adenocarcinoma cells. Molecular Human Reproduction 3: 1019-1027, 1997.
66. Haimov-Kochman R., Laufer N. and Milwidsky A.: Cesarean section for severe fetal distress in a woman with diabetic ketoacidosis. Israel J. Obstet. Gynecol. 9,2,164-187, 1998.
67. Haimov-Kochman R., Bauminker R. and Milwidsky, A.: Prevention of perinatal group B streptococcus disease in light of an unknown maternal carriage rate in Israel. Harefuah, Accepted for publication, 1999.
68. Hanoch Y., and Milwidsky A: Aggressive vulvar angiomyxoma: A case report. Acta Obstet. Gynecol. Scand. Accepted for publication, 2000.
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