Institute of Gastroenterology
Hadassah Hebrew University Medical Center
Ein Kerem, Jerusalem, 91120, Israel.
Home phone: 972-2-5790750
Cellular: 972-50-8573696
Work phone: 972-2-6778511
Fax: 972-2-6420338
Personal Details
Date of birth: 23rd December 1973
Country of birth: Israel.
Nationality:Israeli
Higher Education
1999: BMedSc, Hebrew University, Jerusalem, Israel.
2003: MD, Hebrew University – Hadassah Medical School, Jerusalem, Israel.
MD thesis: Color Contrast Sensitivity after Laser in Situ Keratomileusis. Instructors: Prof J. Frucht, Dr. I. Keizerman.
Appointments at the Hebrew University
2007: "Academic Instructor", Hebrew University – Hadassah Medical School.
Additional Functions/Tasks at the Hebrew University
2003–2004: Medical internship, Hadassah Medical Center, Jerusalem, Israel.
2004–2008: Internal medicine residency program, Hadassah Medical Center.
2007–to date: Israeli liver transplant committee
2007-to date: Liver transplantation coordinator, Hadassah Medical Center.
2008: Chief Resident, Department of Medicine, Hadassah Medical Center
Awards
2000: Ambassadors Exchange program, Knoxville & Memphis Tennessee. Completed with distinction.
2006: European Association for the Study of the Liver (EASL) – Vienna 2006 convention – Young investigator research award.
2007: Israel Association for the Study of the liver (IASL) – Young investigator award.
2007: European Association for the Study of the Liver (EASL) – Barcelona 2007 convention – Young investigator research award.
2007: Digestive Disease Week (DDW) – Washington 2007 convention – Career Development presentation.
2007: Banff Conference on Allograft Pathology – La Corona, Spain, 2007 Convention – Invited Lecture.
2007: American Association for the Study of Liver Diseases (AASLD) – Boston, 2007 Convention – Young Investigator Award.
2008: Israel Association for the Study of the liver (IASL) – Young investigator award.
2008: European Association for the Study of the Liver (EASL) – Milan 2008 convention – Young investigator research award.
2009: European Association for the Study of the Liver (EASL) – Copenhagen 2009 convention – Young investigator research award.
2009: Hebrew University, School of Medicine, Faculty prize for "Distinction in Clinical Work" 2009.
Research Grants
Salzburg Foundation. Hadassah Hebrew University Medical Center. "Suppression of hepatocellular carcinoma via administration of beta glycolipids". Gadi Lalazar MD. 8000$
Joint grant ("meshutefet"). Hadassah Medical Center and the Hebrew University. "Tetrahydrocanabinol for the treatment of hepatic encephalopathy" Gadi Lalazar MD, Yosefa Avraham PhD. 10,000$
Teaching at the Hebrew University
Courses taught at HU:
1996–2001: Bachelor's – Computer course
2000–2002: Bachelor's – Computer course coordinator
1997–1999: Bachelors' – Anatomy instructor
1997–1998: Bachelor's – Histology instructor
2004–2008: MD – Fourth year medicine – clinical instructor
2004–2008: MD – Sixth year medicine – clinical instructor
2007-2008: Masters – School of nursing – Intensive care nursing.
2007–2008: Masters – School of pharmacology – "Disease processes"
2007–2008: MD – Teaching coordinator fourth year medicine
Supervision of MD research project
2007: Eliakim-Raz Noa – The effect of oral glycolipids on TNBS colitis. Completed with honors – Faculty prize for MD research project.
2008: Lador Adi – The effect of glycolipids on concanavalin A induced hepatitis. Completed with honors – Faculty prize for MD research project.
2008: Shachar Yair - Liver breath test in patients with Non-Alcoholic steatohepatitis (NASH): A non invasive alternative to liver biopsy. Completed – final score 92.
2008: Weinstein Olga - The effect of glycolipide β-glucosylceramide on development of B16 melanoma in a murine model. Submitted.
2008: Tehila Hajaj - Assessment of liver injury using 13C-Methacetin breath test in patients with chronic HCV infection and normal liver enzymes. Completed – final score 90.
Patents
2008: Combination of Glycolipids – IGL – for the treatment of autoimmune disorders
2008: Alginate Scaffolds for liver regeneration
2008: Immune regulation with oral feeding of cow derived antibodies
List of Publications
Chapters in Collections:
1. Adar T, Ben Ya'acov A, Lalazar G. Optimizing the use of Beta Glycolipids as NKT cell Ligands. Natural Killer T Cells – Roles, Interactions and Interventions. Chapter 8; pp. 173-187. Editor: Nathan V. Fournier. Nova Biomedical.
2. Lalazar G, Shouval D. Screening Prevention and Treatment of Hepatitis B Virus Reactivation in Hemato-Oncologic and Immune Suppressed Patients at Risk. Hepatite B. Editors: Jean-Michel Pawlotsky et Daniel Dhumeaux. EDK, Sèvres, France. (in French).
Articles:
Original Papers in Peer Reviewed Journals:
Zigmond E, Preston S, Pappo O, Lalazar G, Shalev Z, Zolotarov L, Friedman D, Alper R, Ilan Y. (2007). glucosyLceramide: A novel method for enhancement of NKT lymphocyte plasticity in murine models of immune mediated disorders. Gut.; 56(1):82-9.
Ilan Y, Ohana M, Pappo O, Margalit M, Lalazar G, Engelhardt D, Rabbani E, Nagler A. (2007). Alleviation of acute and chronic graft versus host disease in a murine model is associated with glucocerebroside enhanced natural killer T lymphocyte plasticity. Transplantation.; 83(4):458-67.
Lalazar G, Pappo O, Hershcovici T, Hadajaj T, Shubi M, Ohana H, Hemed N, Ilan Y. (2008). A continuous 13C Methacetin breath test for non invasive assessment of intrahepatic inflammation and fibrosis in patients with chronic HCV infection and normal ALT. J Viral Hepat.; 15(10):716-28.
Lalazar G, Ben Ya'acov A, Eliakim N, Livovsky DM, Pappo O, Preston S, Zolotarov L, Ilan Y. (2008). β-glycosphingolipids-mediated Lipid Raft Alteration is associated with redistribution of NKT cells and increased intrahepatic CD8+ T lymphocyte trapping. J Lipid Res.; 49(9):1884-93.
Lalazar G, Ben Ya'acov A, Lador A, Livovsky DM, Pappo O, Preston S, Hareati M, Ilan Y. (2008). Modulation of intracellular machinery by β-glycolipids is associated with amelioration of concanavalin-induced hepatitis. Mol Immunol.; 45(13):3517-25.
Livovsky DM, Lalazar G, Ben Ya'acov A, Pappo O, Preston S, Zolotaryova L, Ilan Y. (2008). Administration of β-glycolipids overcomes an unfavorable nutritional dependent host milieu: A role for a soy-free diet of diet and natural ligands in intrahepatic CD8+ lymphocyte trapping and NKT cell redistribution. Int Immunopharmacol.; 8(9):1298-305.
Mizrahi M, Lalazar G, Ben Ya'acov A, Livovsky DM, Horowitz Y, Zolotarov L, Adler R, Shouval D, Ilan Y. (2008). Beta-glycosphingolipid-induced augmentation of the anti-HBV immune response is associated with altered CD8 and NKT lymphocyte distribution: a novel adjuvant for HBV vaccination. Vaccine.; 26(21):2589-95.
Zigmond E, Zangen S, Pappo O, Sklair-Levy M, Lalazar G, Zolotaryova L, Raz I, Ilan Y. (2009). Beta-glycosphingolipids improved glucose intolerance and hepatic steatosis of the Cohen diabetic rat. Am J Physiol Endocrinol Metab.; 296(1).
Lalazar G, Ben Ya'acov A, Livovsky DM, El Haj M, Pappo O, Preston S, Zolotarov L, Ilan Y. (2009). Beta-glycosphingosphingolipid-induced alterations of the STAT signaling pathways are dependent on CD1d and the lipid raft protein flotillin-2. Am J Pathol; 174(4):1390-9.
Lalazar G, Adar T, Ilan Y. (2009). Point of care continuous 13C Methacetin breath test improves decision making in acute liver disease: results of a pilot clinical trial. World J Gastroenterol; 15(8):966-72.
Case Reports:
Gur C, Lalazar G, Raphaeli G, Gilon D, Ben-Chetrit E. (2006). Mitral stenosis presenting with acute hearing loss. PLoS Med; 3(6):e233. 12.601;6/100;0.
Gur C, Lalazar G, Doviner V, Fridlender ZG, Abu-Much S, Ilan Y, Shalit M; Elinav E. (2007). Late onset Sarcoidosis following liver transplantation for Primary Biliary Cirrhosis. J Clin Gastroenterol.; 41(3):329-32. 2.938.
Gur C, Lalazar G, Salmon A, Dubiner V, Gross DJ. (2009). Metastatic pancreatic neuroendocrine tumor presenting as a pituitary space occupying lesion: a case report. Pituitary. 11(3):293-7. 0;0;0.
Mizrahi M, Lalazar G, Horowitz Y, Adar T, Safadi R. (2008). Benign Recurrent Intraheptic Cholestasis type II, a rare cause of direct hyperbilirubinemia exacerbations, with hepatic fibrosis. Harefua.; 147(5):381-3, 480. Hebrew.
Samuel N, Lalazar G, Shuvy M, Mizrahi M, Granados J, Elami A, Uzi I, Liebowitz G, Ilan Y, Berkman N. Successful use of streptokinase for the treatment of empyema thoracis during advanced pregnancy: A case report. (2009). Respiratory Medicine; 2:21-4.
Elias S, Lalazar G, Shouval D. Post traumatic primary sclerosing cholangitis.(2009). Harefua. 184(4):157-9.
Reviews, commentaries, hypotheses, editorials:
Lalazar G, Ilan Y. (2006). Histamine dihydrochloride: actions and efficacy in the treatment of chronic hepatitis C infection. Expert Rev Anti Infect Ther.; 4(3):377-85. 0;0;1.
Lalazar G, Preston S, Zigmond E, Ben Ya`acov A, Ilan Y. (2006) Glycolipids as immune modulatory tools. Mini Rev Med Chem.; 6:1249-53. 3.060;9/41;10.
Lalazar G, Rund D, Shouval D. (2007). Screening, prevention and treatment of viral hepatitis b reactivation in patients with haematological malignancies. B J Haematol.; 136(5): 699-712. 4.490; 12/63;22.
El Haj M, Ben Ya'acov A, Lalazar G, Ilan Y. (2007). Potential role of NKT regulatory cell ligands for the treatment of immune mediated colitis. World J Gastroenterol.; 13(44):5799-804.
Adar T, Rubinger GD, Lalazar G, Levy L, Mizrahi M, Bogat N. (2008) Nephrogenic systemic sclerosis. Harefua.; 147(10):801-3, 837. Hebrew.
Abstracts Presented
1. Lalazar G, Keizerman I, Lalazar H, Frucht-Perry J. Color Contrast Sensitivity After LASIK. Oral presentation –ISVER XXV Annual Meeting. March 2005. Israel.
2. Lalazar G, Mirkeen D, Gilon D, Pollack A, Durst R, Marincheva G, Lotan C. Amplatzer device closure of a complex ASD, a controlled stepwise approach. Oral presentation – Intercad 2004. Israel.
3. Lalazar G, Preston S, Eliakim N, Pappo O, Zolotarov L, Ilan Y. Redistribution of intrahepatic NKT regulatory lymphocytes via administration of beta glycolipids: a possible role for the liver in the alleviation of immune mediated disorders. Oral presentation – Israel association for the study of the liver March 2006. Eilat – Israel.
4. Lalazar G, Preston S, Eliakim N, Pappo O, Zolotarov L, Ilan Y. Redistribution of intrahepatic NKT regulatory lymphocytes via administration of beta glycolipids: a possible role for the liver in the alleviation of immune mediated disorders. Oral presentation – EASL 2006. Vienna – Austria.
5. Lalazar G, Preston S, Lador A, Pappo O, Ilan Y. Beta glycolipids in conA hepatitis and alterations in the Th1:Th2 paradigm. Poster presentation – EASL 2006. Vienna – Austria.
6. Lalazar G, Shuvy M, Pappo O, Margalit M. Methacetin breath test for follow up in acute liver failure. Poster presentation – EASL 2006. Vienna – Austria.
7. Lalazar G, Ben Ya’acov A, Preston S, Lador A, Pappo O, Zigmond E, Zolotarov L, Ilan Y. Alteration in lymphocyte lipid raft composition and structure via bet glycolipids is associated with amelioration of concanavalin A induced hepatitis: a novel therapy for immune mediated liver disorders. Poster presentation - AASLD 2006 – Boston, USA.
8. Lalazar G, Preston S, Eliakim N, Ben Ya’acov A, Pappo O, Zigmond E, Ilan Y. Redistribution of intrahepatic NKT regulatory lymphocytes and increased intrahepatic T lymphocyte trapping: a possible mechanism for the beneficial effect of beta glycolipids in immune mediated disorders. Oral presentation - AASLD 2006 – Boston, USA.
9. Lalazar G, Hershcovici T, Pappo O, Hajjaj T, Zigmond E, Shuvy M, Ohana H, Hemed N, Margalit M. Accurate identification of liver fibrosis by a continuous 13C Methacetin breath test in patients with chronic HCV infection and normal or near-normal liver enzymes. Poster presentation - AASLD 2006 – Boston, USA.
10. Lalazar G, Ben Ya’acov A, Zigmond E, Preston S, Zolotarov L, Ilan Y, Margalit M. Suppression of hepatocellular carcinoma by beta glycolipids is associated with alteration of lipid raft composition in splenocytes. Poster presentation - AASLD 2006 – Boston, USA.
11. Zigmond E, Lalazar G, Pappo O, Zangen SW, Levy Sklair M, Hemed N, Thalenfeld B, Engelhardt D, Rabbani E, Raz I, Ilan Y, Margalit M. Treatment of non-alcoholic steatohepatitis by beta glucosylceramide: a phase I/II clinical study. Poster presentation - AASLD 2006 – Boston, USA.
12. M Braun, Pappo O, Margalit M, Lalazar G, Zuckerman E, Kitai Y, Barak N, Dan A, Cohen O, Schmilovitz Weiss H, Rotman Y, Zamir D, Melnik S, Tur-Kaspa R, Ben-Ari Z. Detection of nonalcoholic steatohepatitis and the extent of hepatic fibrosis with the innovative real-time BreathID® test system in patients with NAFLD. Poster presentation - AASLD 2006 – Boston, USA.
13. Lalazar G, El Nabi M, Ilan Y, Shteyer E. Beta glucosylceramide decreases liver regeneration after partial hepatectomy in mice: a potential role for NKT regulatory lymphocytes. Poster presentation - AASLD 2006 – Boston, USA.
14. Lalazar G, El Nabi M, Ilan Y, Shteyer E. Beta glucosylceramide alters NKT regulatory lymphocytes and decreases liver regeneration after partial hepatectomy in mice. Poster presentation – EASL 2007 – Barcelona, Spain.
15. Lalazar G, Ben Ya'acov A, Harati M, Ilan Y. Optimization of beta glycolipid structure for suppression of hepatocellular carcinoma in mice: a role for the sphingosine chain length in altering NKT lymphocyte associated anti tumor effect. Poster presentation – EASL 2007 – Barcelona, Spain.
16. Lalazar G, Braun M, Ben-Ari Z, Mullhaupt B, Goetze O, Pappo O, Margalit M. A non invasive 13C methacetin breath test accurately detects liver fibrosis in patients with chronic HCV or non alcoholic fatty liver disease. Poster presentation – EASL 2007 – Barcelona, Spain.
17. Lalazar G, Ben Ya'acov A, Eliakim N, Preston S, Pappo O, Zigmond E, Zolotarov L, Ilan Y. Redistribution of intrahepatic NKT regulatory lymphocytes and increase intrahepatic T lymphocyte trapping: A possible mehcanism for the beneficial effect of beta glycolipids in immune mediated disorders. Oral presentation – IASL 2007, Israel.
18. Lalazar G, Shouval D, Ilan Y, Ashur Y, Galun E, Levi I, Shibolet O, Daudi N, Safadi R. Hepatitis B virus recurrence after liver transplantation: the Hadassh experience. Oral presentation – IASL 2007, Israel.
19. Lalazar G, Pappo O, Mullhaupt B, Goetze O, Margalit M. Point of care non invasive 13C methacetin breath testing accurately identifies significant liver inflammation and fibrosis: a novel method for assessing liver damage. Oral presentation – DDW 2007, Washington, USA.
20. Lalazar G, Zolotorovya L, Pappo O, Ilan Y. Optimization of beta glycolipids for alleviation of immune mediated colitis: a role for different combinations in altering NKT lymphocyte associated immune modulatory . Poster presentation – DDW 2007, Washington, USA.
21. Lalazar G, El Nabi M, Ilan Y, Shteyer E. Beta glucosylceramide delayes fat accumulation and liver regeneration after partial hepatectomy. Poster presentation – DDW 2007, Washington, USA.
22. Lalazar G, Pappo O, Mullhaupt B, Goetze O, Margalit M. Point-of-care non-invasive 13C methacetin breath testing accurately identifies significant liver inflammation and fibrosis: a novel method for assessing liver damage. Poster presentation – DDW 2007, Washington, USA.
23. Israeli E, Margalit M, Lalazar G, Shibolet O, Nilla H, Klein A, Goldin E, Ilan Y. Treatment of Crohn's disease by oral administration of Alequel, a mixture of autologous colon extracted proteins: results of a double blind clinical trial.
24. Lalazar G, Adar T, Ilan Y. Follow-up of Patients with Severe Acute Liver Disease Using an On-line 13C Methacetin Breath Test: A New Tool for Decision Making in Clinical Hepatology. Poster Presentation – AASLD 2007, Boston, USA.
25. Lalazar G, Ben Ya'acov A, Hareati M, Ilan Y. Decreased Intrahepatic CD8 Trapping is Associated with Suppression of Hepatocellular Carcinoma: A Role for the Beta Glycolipid Acyl Chain Length. Poster Presentation – AASLD 2007, Boston, USA.
26. Lalazar G, Pappo O, Ilan Y. Accurate Identification of Liver Fibrosis Using the Point-Of-Care Continuous 13C Methacetin Breath Test: A Decision Making Tool in the Treatment of Patients with Chronic HCV Infection. Poster Presentation – AASLD 2007, Boston, USA.
27. Lalazar G, Ben Ya'acov A, El-Haj M, Livovsky DM, Pappo O, Schwartzman G, Ilan Y. Potentiation of the inhibitory effect of intrahepatic NKT lymphocytes by a novel non-degradable beta-glucosylceramide analog is associated with decreased STAT 1 phosphorylation. Poster Presentation – AASLD 2007, Boston, USA.
28. Lalazar G, Ben Ya'acov A, El-Haj M, Livovsky DM, Pappo O, Ilan Y. Beta-glucosylceramide attenuates the immune-mediated damage of alpha-galactosylceramide in a CD1d receptor dependent manner: A ligand dependent effect on NKT regulatory lymphocytes. Poster Presentation – AASLD 2007, Boston, USA.
29. Lalazar G, Ben Ya'acov A, Livovsky DM, Preston S, Ilan Y. A Combination of beta-glycolipids overcomes a CD1d dependent inhibition of NKT lymphocytes: An alternative Flotillin-2 raft protein dependent regulatory cell activation pathway. Oral Presentation – AASLD 2007, Boston, USA.
30. El-Haj M, Lalazar G, Ben Ya'acov A, Katzniel-Gilad M, Leibowitz G, Ilan Y. Potentiation of Peripheral Insulin Sensitivity in Ob/Ob Mice by Beta-Glycolipids is Mediated by IRS-1 mTOR Signaling Pathways: A Novel Therapeutic Target for NASH. Oral Presentation – AASLD 2007, Boston, USA.
31. Lalazar G, Zigmond E, Ben Ya'acov A, Livovsky DM, Admon E, Gheber L, Fich A, Pappo O, Ilan Y. Decreased GM1 Expression in Membrane Lipid Raft in CD4 and CD8 Cells of Patients with NASH: A Potential Biomarker and Therapeutic Target. Oral Presentation – AASLD 2007, Boston, USA.
32. Lalazar G, Ben Ya'acov A, Livovsky DM, Zigmond E, Ilan Y. Alterations in Lymphocyte Lipid Raft Composition and Structure via Beta Glycolipids is Associated with Amelioration of Non Alcoholic Steatohepatitis: A Novel therapeutic Target for NASH. Poster Presentation – AASLD 2007, Boston, USA.
33. Lalazar G, Pappo O, Safadi R, Ashur Y, Mullhaupt B, Goetze O, Ilan Y. Accurate identification of liver fibrosis in chronic HCV patients using a continuous 13C methacetin breath test: A validation study of a novel decision making tool. Poster Presentation – EASL 2008, Milan, Italy.
34. Lalazar G, Pappo O, Safadi R, Ashur Y, Mullhaupt B, Goetze O, Ilan Y. The 13C Methacetin Breath Test Accurately Indentifies Liver Fibrosis in patients with chronic HCV infection: A validation study. Oral Presentation – Presedential Plenary session – DDW 2008, San Diego, USA.
35. Adar T, Lalazar G, Ben Ya'acov A, Mizrahi M, Steyer E, Kanovich D, Axelrod E, Lichtenstein, Zolotaryova L, El Haj M, Dagan A, Ilan Y. A Beta Glycosphingolipid Analogue Ameliorates Immune Mediated Hepatitis Via a Type I NKT Dependent Mechanism and Supression of STAT4 Expression: A Novel Liver Directed, Steroid Equivalent Immune Modulatory Agent. Oral Presentation – AASLD 2008, San Francisco, USA.
36. Steyer E, Lalazar G, Ben Ya'acov A, Zolotaryova L, Lichtenstein Y, Kryukov O, Elkayam T, Cohen S, Ilan Y. Reduced Liver Cell Death Using a Bandage of Alginate Scaffold: A Novel Approach for Liver Reconstruction During Acute Hepatic Failure in Mice. Poster Presentation – AASLD 2008, San Francisco, USA.
37. Lalazar G, Adar T, Mizrahi M, Zigmond E, Taylor NJ, Chan-Dominy AC, Wendon J, Ilan Y. Follow up of Patients with Severe Acute Liver Disease Using an On line 13C Methacetin Breath Test: A New Tool for Decision Making in Clinical Hepatology. Poster Presentation – AASLD 2008, San Francisco, USA.
38. Chan-Dominy AC, Lalazar G, Taylor NJ, Adar T, Mizrahi M, Zigmond E, Sizer E, Auzinger G, Bernal W, Ilan Y, Wendon J. Use of an On line 13C Methacetin Breath Test in Liver Failure: Clinical Experience and Correlations. Poster Presentation – AASLD 2008, San Francisco, USA.
39. Lalazar G, Ben Ya'acov A, Lichtenstein Y, Zolotaryova L, Ilan Y, Shteyer E. Amelioration of Fat Accumulation During Liver Regeneration by TNFalpha-IL6-STAT3 Cascade Suppression Mechanism. Poster Presentation – AASLD 2008, San Francisco, USA.
40. Mizrahi M, Lalazar G, Ben Ya'acov A, Adar T, Zolotaryova L, Ilan Y. CD4+LAP+ Regulatory T Cells Mediate Enhancement of the anti HBV Immune Response: A Novel Method for an Adjuvant Dependent Augmentation of Anti Viral Immunity. Poster Presentation – AASLD 2008, San Francisco, USA.
41. Lalazar G, Keidar A, Adar T, Mizrahi M, Zigmond E, Hemed N, Ilan Y. Assessment of Hepatic Mitochondrial Beta Oxidation Using the Non Invasive 13C Octanoate Breath Test: A Novel Tool for Assessment of Liver Function Before and After Bariatric Surgery. Poster Presentation – AASLD 2008, San Francisco, USA.
42. Zigmond E, Tayer-Shifman O, Lalazar G, Pappo O, Ben Ya'acov A, Zangen SW, Shasha D, Sklair-Levy M, Zolotaryova L, Shalev Z, Kalman R, Ziv E, Raz I, Ilan Y. Decrease STAT 1,4 and Increase STAT 5 Expression is Associated with Amelioration of Steatohepatitis in Psammomys Obesus: A Mechanism for Beta Glycosphingolipid Mediated Improvement of Insulin Resistance. Poster Presentation – AASLD 2008, San Francisco, USA.
43. Lalazar G, Ben Ya'acov A, Admon E, Gheber L, Fich A, Pappo O, Ilan Y. Increased Insulin Receptor and Decreased GM1 Expression in Membrane Lipid Rafts of Patients with NASH: A Potential Biomarker and Therapeutic Target. Presentation – AASLD 2008, San Francisco, USA.
44. Lalazar G, Ben Ya'acov A, El Haj M, Livovsky DM, Ilan Y. STAT Signaling Pathway Can Be Determined by Optimization of the Beta Sphingolipid Structure: A Novel Method for the Fine Tuning of an NKT Dependent Immune Regulation. Poster Presentation – AASLD 2008, San Francisco, USA.
45. Lalazar G, Ben Ya'acov A, Zolotaryova L, Axelrod E, Ilan Y. Type II Non Classical NKT Lymphocytes Induce, While Type I Classical NKT Lymphocytes Suppress Liver Mediated CD4 Trapping Dependent Peripheral Tolerance Induction: A Role For the Alteration of Membrane Lipid Rafts On Dendritic Cells. Poster Presentation – AASLD 2008, San Francisco, USA.
46. Lalazar G, Adar T, Mizrahi M, Zigmond E, Hemed N, Ohana H, Rowe M, Ilan Y. Shiffman ML. The Point of Care 13C Methacetin Breath Test Accurately Predicts Long Term Prognosis in Cirrhotic Patients: A Non Invasive Liver Function Test. Poster Presentation – AASLD 2008, San Francisco, USA.
47. Orenbuch-Harroch E, El Haj M, Ben Ya'acov A, Lalazar G, Zigmond E, Kanovitch D, Ilan Y. Oral Administration of Anti CD3 Monoclonal Antibodies Promotes CD4+CD25+LAP+ and NKT LAP+ Regulatory T Lymphocytes and Ameliorates Hepatitis by Inhibiting Caspase 3 Mediated Apoptosis. Oral Presentation – EASL 2009, Copenhagen, Denmark.
48. Lalazar G, Muellhaupt B, Adar T, Goetze O, Mizrahi M, Zigmond E, Hemed N, Rowe M, Ilan Y. Decision Making in Clinical Hepatology Using the 13C Methacetin Breath Test: Results of a 614 Patient Clinical Trial. Oral Presentation – DDW 2009, Chicago, USA.
49. Israeli E, Zigmond E, Lalazar G, Klein A, Hemed N, Ilan Y. Oral Administration of Alequel, a Mixture of Autologous Colon Extracted Proteins for Treatment of Crohn's Disease: Results of a Double Blind Clinical Trial. Oral Presentation – DDW 2009, Chicago, USA.
50. Lalazar G. Type II Non Classical NKT Lymphocytes are Crucial for Alleviation of TNBS Induced Immune Colitis: A Role for the Alteration of Membrane Lipid Rafts on Dendritic Cells. Oral Presentation – DDW 2009, Chicago, USA.