Dr. Juri Kopolovic, MD

I began my medical education at the P.J. Safarik School of Medicine in Kosice, Czechoslovakia in 1964, planning to make aliyah after finishing my medical education. But while I was enrolled in medical school, the spring 1968 Prague uprising opened a window for emigration, and I came to Israel with my wife. After six months of ulpan, I enrolled in the Hebrew University – Hadassah School of Medicine in 1969, completed my internship at Hadassah in 1972, and began my residency in the Department of Pathology at Hadassah in 1973. Both my residency and preparation of my medical thesis were interrupted by the Yom Kippur War, during which I served as a physician on the Egyptian front. After the war I continued my residency, completing my medical thesis and receiving my MD in 1976.

During my residency I became interested in nephropathology. In 1977 my mentor, Prof Alexander Laufer, Chairman of Pathology at that time, sent me to Professor Jacob Churg for a clinical fellowship at Mt Sinai School of Medicine in New York. Professor Churg was a world-renowned leader in nephropathology. At Mt Sinai I also worked and trained as a general pathologist. In 1978 I returned to Jerusalem and the Department of Pathology at Hadassah, and completed my Board Certification in Pathology. I joined Hadassah’s Department of Pathology as an attending pathologist with special interest specialist in nephropathology. In 1980 I spent three months at the Karl Eberhardt University, Tubingen, Germany under Professor Bohle, an eminent nephropathologist. In the ensuing years I have worked in nephropathology, while being actively engaged in research, teaching inflammation, gynecopathology, and nephropathology to medical students and young physicians.

From 1986 – 1988 I continued my advanced training with a research and clinical fellowship in nephropathology at Beth Israel Hospital, of the Harvard School of Medicine in Boston. During these years I was also an Instructor at the Harvard School of Medicine. In addition to my full clinical responsibilities in general pathology at Beth Israel, I conducted research focusing on morphological changes in isolated perfused kidneys of rats under various experimental conditions.

During these years we published several articles (original articles 19, 22, 23, case report 32). My most important work in Boston was to evaluate morphological changes along the nephron in response to hypoxia and reperfusion. In an attempt to ameliorate the effect of hypoxia in the isolated, perfused kidney, polyethylene glycol (PEG) was added to the perfusate in oxygenated and hypoxic kidneys. PEG produced similar changes in the S1-S2 segment, which consisted of reduction of cell thickness, organelle compaction, and internalization of brush border in the tubulovesicular system. In the S3 segment, the cellular volume loss was more limited, the brush border was transformed to membranous whorls and the cytoplasm contained large irregular clear zones. Mitochondrial swelling was pronounced. It was demonstrated that PEG does not protect against hypoxic injury. (original article 22). Thus mild-moderate hypoxic changes in isolated perfused kidneys can be reversible, whereas severe change is irreversible. Moderate injury to the medullary, thick, ascending limb has the capacity to regress in acute renal failure, because morphological changes are limited.

Upon returning to Israel in 1988, I joined the Wolfson Medical Center in Holon as Chairman of Department Pathology. Wolfson is an affiliate hospital of the Sackler School of Medicine of Tel Aviv University. After two busy clinical years in Holon, in 1991 I was invited to become Chairman of the Department of Pathology at Sheba (Tel HaShomer) Medical Center, also an affiliate of the Sackler School of Medicine of Tel Aviv University.

During my tenure as Chairman of Pathology at Sheba I reorganized the Department, introducing subspecialities in neuropathology, hematopathology, gastrointestinal pathology, lung pathology, genitourinary and prostatic pathology, breast, and of course nephropathology. I also brought new methodologies in clinical pathology, including immunohistochemical and molecular analysis for clinical application across the pathological subspecialties at Sheba. We began to routinely use techniques in immunofluorescence, electron microscopy, and fluorescent in situ hybridization (FISH) in the Department, for both diagnostic and research purposes. We brought three PhD biologists into the Department to support our clinical service and participate in research programs. They head laboratory programs for routine pathological examinations, as well as molecular and immunohistochemical studies.

We now conduct weekly multidisciplinary meetings in a number of these subspecialty areas, and physician subspecialists teach at the Sackler School of Medicine of Tel Aviv University. I am a Clinical Professor at the Sackler School of Medicine, responsible for teaching a course in nephropathology in both the Israeli and American programs. Today the Department processes surgical specimens for 25,000 patients per year across the medical specialties. 

During my first decade as Chairman at Sheba, my first focus was on building infrastructure and expertise in multiple subspecialty areas within the larger field of Pathology. During these years I was also a very busy clinical pathologist myself, working within my nephropathology subspecialty as well as in general pathology. However research and teaching have remained central to my role as a Pathologist and as Chairman.

Research

During my years at Sheba I was privileged to be a member of several close-knit teams of active scientists, with research focused on three areas: autoimmunity, atherosclerosis, and extracellular matrix in malignancies of the female genital tract. My role in this research encompassed defining research objectives and programs, interpretation of the morphological findings, conducting experiments, reaching conclusions, and writing the papers.

Autoimmunity  We have shown in an experimental SLE model that mice experienced complete clinical and morphological remission following treatment with intravenous gamma globulin. Our results suggest a possible clinical application of intravenous gamma globulin preparations containing antiidiotypic activity to anti DNA and aCL in patients with SLE or anti-phospholipid syndrome (original article 34).

To better understand autoimmune diseases we employed an experimental murine model for evaluation of autoimmune vasculitis. We demonstrated that active immunization of naïve mice with WG patient-derived AECA leads to the development of circulating mouse anti-endothelial cell antibodies, and a vasculitis-like disorder in immunized mice. This animal model of vasculitis provides the first direct proof of the pathogenicity of anti-endothelial cell antibodies (original article 41).

A variety of additional research focused on other experimental and morphological aspects of autoimmunity (original articles 33, 40, 41, 67)

Atherosclerosis  We showed enhanced atherosclerosis and a clear difference in plaque formation between β2GPI immunized mice and a control group. In addition, the atherosclerotic plaques of Apo-E deficient mice were rich in CD4+, CD8+, and macrophages, which may play an active role in the development of disease. This study provided experimental evidence for the role of the immune response against β2GPI in initiation and progression of atherosclerosis (original article 66).

In other research we found that β2GPI was abundantly expressed in the subendothelial region and the intimal-media junction in human atherosclerotic plaque. CD4+ lymphocytes densely infiltrated the areas in which β2GPI was expressed, while there was a relative paucity of CD8+ lymphocytes. The presence of β2GPI together with CD4+ lymphocytes in human atherosclerotic plaque may serve as a target for an immune-mediated reaction that can influence lesion progression (original article 77).

We have pursued further research to understand the role of immunity in the development and progression of atherosclerosis (original articles 56, 67, 71, 77, 78, 81, 88)

The extracellular matrix in malignancies of the female genital tract  In the last few years I and my colleagues studied the role of the extracellular matrix in local invasion, metastasis, angiogenesis, and prognosis in female genital tract malignancies. We found that three proteins – matrix metalloproteinase-2 (MMP2), the tissue inhibitor of metalloproteinase-2 (TIMP-2), and membrane-type metalloproteinase (MT1-MMP) – were upregulated in invasive carcinoma compared to carcinoma in situ and control cervices. When they are present, these proteins are associated with aggressive tumors and are markers of poor prognosis (original article 75).

In serous effusions of ovarian cancer, we analyzed the expression of MMP-2, MT1-MMP, MT2-MMP, and MT3-MMP mRNA. Production of these enzymes may enhance extracellular matrix degradation of peritoneal tissue, and possibly facilitate cancer cell invasion of abdominal structures (original article 115).

The expression of mRNA of MMP, TIMP-2, and angiogenic genes was evaluated in tumors from patients with advanced-stage ovarian carcinoma. mRNA expression of TIMP-2 was a marker of poor prognosis. This supports the central role of metalloproteinases in local invasion and distant metastases. The lack of correlation between the angiogenic gene expression and survival may have a profound therapeutic implications (original article 109).

We have reported our findings regarding the role of the extracellular matrix in progression and prognosis for female genital tract malignancies in many other publications (original articles 60- 63, 76, 83-86, 99-101, 103, 108-110, 115, 121, 125, 126).

Teaching

As Chairman, I directed Israeli and American 3^rd and 4^th medical student rotations in the Department of Pathology at the Sheba Medical Center for the Sackler School of Medicine of Tel Aviv University. In addition I taught Nephropathology with the accompanying course Laboratories in Nephropathology to the Israeli and American medical students at Sackler. Immediately after assuming the Chairmanship at Sheba, I introduced an active residency program into the Department of Pathology, and I directed this program throughout my years as Chairman, training 10 residents through receipt of full board certification. In 1995 and 1998 I gave a course in nephropathology to pathology residents in Sackler’s Postgraduate School of Medicine. I also mentored the advanced research efforts of several residents and MSc students during my years at Hadassah and Sheba. While on my fellowship at Harvard I taught nephropathology, and earlier, in the years at Hadassah, I taught Nephropathology, Gynecological Pathology, and General Pathology (Inflammation and Amyloidosis) to 3^rd year medical students at the Hebrew University – Hadassah School of Medicine.

In the next years I will again combine intensive administrative work as the incoming Chairman of Hadassah’s Department of Pathology with active research efforts. At Hadassah I will also remain active training residents in Pathology as the leader of this important program in my new Department. On the research front I intend to investigate the expression of other transcription factors such as Snail and Sp 1 (specificity protein 1) in short- and long-term survivors of ovarian carcinoma. Sp 1 plays a critical role in the growth and metastasis of many tumor types by regulating expression of cell cycle genes and vascular endothelial growth factors. In addition we are planning to evaluate the phosphatidylinositol 3’-kinase-Akt signaling pathway, which regulates fundamental cellular functions such as transcription, translation, proliferation, growth, and survival in primary ovarian cancer. We will compare our results with results from comparable studies of metastatic carcinoma as well as with the cells in effusions.

I look forward to building on the solid base in the Department of Pathology that has been established by Professor Dov Soffer, as I return to my roots at Hadassah.

List of Publications

Books Edited

Chapters in Collections

1.                  Weshler Z, Gotsman MS, Okon E, Pizoff G, Kopolovic J, Biran S, Eldor A. (1990) Inhibition by irradiation of smooth muscle cell proliferation in the de-endothelialized rat aorta. In: Riklis E. (ed) Frontiers in radiation biology, 21^st annual meeting of the European Society for Radiation Biology, pp133-138. Balaban Publ, Tel Aviv, Israel.

2.                  Kopolovic J. (1992) Peripheral vascular disease: normal morphology and pathological considerations. In: Kim D and Oron D (eds) Peripheral vascular disease and intervention, pp 39-49. Mosby Inc., Baltimore, MD.

Original Papers in Peer Reviewed Journals

PI         Principle Investigator

S          Student

C         Co-researcher

T          Technician/laboratory assistant

1.                  Kopolovic J^PI, Fields M^C, and Laufer A^PI. (1978) Effects of papain on experimental amyloidosis. Experientia 34:524-535,  2.072;  8/51;1.

2.                  Gatt S^PI, Dinur T^PI, and Kopolovic J^PI. (1978) Niemann Pick disease: presence of the magnesium-dependent sphingomyelinase in brain of the infantile form of the disease. J Neurochem 31(2):547-550. 4.604  51/261;  28/200;  25;  25

3.                  Friedman G^PI, Granot H^C, Kopolovic J^C, and Friedlaender M^PI. (1981) "Pulse" methylprednisone and cyclophosphamide therapy in idiopathic rapidly progressive glomerulonephritis. Postgrad J Med 57:54-56.  0.659;  65/105;  0

4.                  Beyth Y^PI, and Kopolovic J^PI. (1982) Accessory tubes: a possible contributing factor in infertility. Fertil Steril 38(3):382-383. 3.114;  6/57;  6/24;  11; 11

5.                  More R^PI, Amir N^C, Meyer S^C, Kopolovic J^C, and Yarom R^PI. (1982) Platelet abnormalities in Down's syndrome. Clin Genet 22(3):128-136. 3.276;  45/124;  6;  6

6.                  Shalev O^PI, Rubinger D^C, Barlatzky Y^C, Kopolovic J^PI, and Drukker A^PI. (1982) Eosinophilia associated with acute allograft kidney rejection. Nephron 31(2):182-183. 1.561;  14/41;  12;  12

7.                  Knobler H^PI, Kopolovic J^PI, Kleinman Y^C, Rubinger D^C, Silver J^C, Friedlaender MM^C, and Popovtzer MM^PI. (1983) Multiple myeloma presenting as dense deposit disease. Light chain nephropathy. Nephron 34(1):58-63. 1.561;  14/41;  12;  12

8.                  Ben-Dov I^PI, Berry EM^PI and Kopolovic J^PI (1985) Poststreptococcal nephritis and acute rheumatic fever in two adults. Arch Intern Med 145(2):338-339.  8.016;  8/105; 7; 7

9.                  Milgalter E^PI, Uretzky G^C, Siberman S^C Appelbaum Y^C, Shimon DV, Kopolovic J^PI, Cohen D^C, Jonas H^C, Appelbaum A^C, and Borman JB^PI. (1985) Pericardial meshing: an effective method for prevention of pericardial adhesions and epicardial reaction after cardiac operations. J Thorac Cardiovasc Surg 90(2):281-286. 3.727;  9/72; 8/33;  8/139;  20;  20

10.              Shalit M^PI, Flugelman MY^C, Harats N^C, Galun E^C, Ackerman Z^C, Kopolovic J^PI, and Eliakim M^PI. (1985) Quinidine-induced vasculitis. Arch Intern Med 145(11):2051-2052.  8.016;  8/105;  16;  16

11.              Rubinger D^PI, Friedlaender MM^C, Silver J^C, Kopolovic J^PI, Czaczkes WJ^C, and Popovtzer MM^PI. (1986) Progressive vascular calcification with necrosis of extremities in hemodialysis patients: a possible role of iron overload. Am J Kidney Dis 7(2):125-129.  4.412;  3/51;  37;  37

12.              Kopolovic J^PI, and Oren R^PI. (1986) IgM nephropathy – clinicopathological entity. Harefuah 110:156-157 [Hebrew].  x;  x;  0

13.              Navot D^PI, Laufer N^C, Kopolovic J^PI Rabinowitz R^C, Birkenfeld A^C, Lewin A^C, Granat M^C, Margalioth EJ^C, and Schenker JG^PI. (1986) Artificially induced endometrial cycles and establishment of pregnancies in the absence of ovaries. N Engl J Med 314(13):806-811. 44.016;  1/105;  158;  158

14.              Rubinger D^PI, Drukker A^C, Shvil Y^C, Kopolovic Y^C Friedlaender MM^C Shalit M^C, and Popovtzer MM^PI. (1986) Combined cyclophosphamide and corticosteroid-induced remission in severe glomerulopathy associated with systemic vasculitis. Am J Nephrol 6(5):346-352. 2.459;  13/51;  6;  6

15.              Friedlander MM^PI, Rubinger D^C, Ben-Chetrit E^C, and Kopolovic J^PI. (1986) IgA nephropathy and acute reversible renal failure. Isr Med Sci J IMAJ 22:888-891 [Hebrew]. 0.456;  62/110;  2;  2

16.              Kopolovic J^PI, Shvil Y^C, Pomeranz A^C Ron N^C, Rubinger D^C, and Oren R^PI. (1987) IgM nephropathy: morphological study related to clinical findings. Am J Nephrol 7(4):275-280.  2.459;  13/51;  16;  16

17.              Weshler Z^PI, Ligumsky M^C, Brufman G^C, Kopolovic J^C, Tochner Z^C, Karmeli F^C, and Rachmilewitz D^PI. (1987) Functional and morphological alterations following isolated rat stomach irradiation. A model for estimation of radiation injury. In Vivo 1(6):357-361. 1.037;  52/72;  1; 1

18.              Gur H^PI, Kopolovic Y^PI, and Gross DJ^PI. (1987) Chronic predominant interstitial nephritis in a patient with systemic lupus erythematosus: a follow up of three years and review of the literature. Ann Rheum Dis 46(8):617-623. 6.956;  2/22;  16;  16

19.              Brezis M^PI, Kopolovic J^PI, and Rosen S^PI. (1988) Hypoxic injury to medullary thick ascending limbs in perfused rat kidneys: reversible and irreversible phases. J Electron Microsc Tech 9(3):293-298.  2.323;  3/15;  13/65;  2/9;  9;  8

20.              Friedlaender MM^PI, Wald H^C, Kopolovic J^C, and Popovtzer MM^PI. (1988) Colchicine does not interfere with the antiphosphaturic effect of 25(OH) vitamin D3 in the rat. Miner Electrolyte Metab 14(2-3):103-109.  1.025;  56/85;  4;  4

21.              Weshler Z^PI, Ligumski M^C, Tochner Z^C, Kopolovic J^C, Carmeli F^C, and Rachmilewitz D^PI. (1988) Functional and morphological alterations following irradiation of isolated rat stomach: a model for estimation of radiation injury. Pharmacol Ther 39(1-3):85-87.  8.357;  6/193;  1;  1

22.              Kopolovic J^PI, Brezis M^C, Spokes K^C, and Rosen S^PI. (1989) Polyethylene glycol effect on the oxygenated and hypoxic isolated perfused rat kidney. Virchows Arch A Pathol Anat Histopathol 414(5):429-437. 2.224;  21/66;  4;  4

23.              Kopolovic J^PI, Brezis M^C, Spokes K^C, Silva P^C, Epstein F^C, and Rosen S^PI. (1989) The vulnerability of the thin descending limbs of Henle’s loop in the isolated perfused rat kidney. Am J Kidney Dis 14(1):25-30.  4.412;  3/51;  0

24.              Bercovici B^PI, Lewin A^C, Rabinowitz R^C, Kopolowitz J^PI, Smilow PC^C, Rosenberg JL^C, and Laufer N^PI. (1988) The cytology of vaginal, cervical and endometrial smears obtained at the time of embryo transfer during in vitro fertilization. Acta Cytol 32(6):789-793. .022;  129/153;  48/66;  2;  2

25.              Smetana S^PI, Khalef S^C, Kopolovic G^C, Bar-Khayim Y^C, Birk Y^C, and Kacew S^PI (1992) Effect of interaction between gentamicin and pyridoxal-5-phosphate on functional and metabolic parameters in kidneys of female Sprague-Dawley rats. Ren Fail 14(2):147-153.   0.540;  45/51;  4;  4

26.              Tepper R^PI, Nahum R^C, Rahamim E^C, Kapolovitz Y^C, Segal Y^C, Karib N^C, and Beyth Y^PI. (1992) Effects of methotrexate on rabbit oviducts and on cell cultures of bovine oviduct epithelium. Gynecol Obstet Invest 33(2):65-68.  0.810;  48/57;  1;  1

27.              Blank M^PI, Faden D^C, Tincani A^C, Kopolovic J^C, Goldberg I^C, Gilburd B^C, Allegri F^C, Balestrieri G^C, Valesini G^C, and Shoenfeld Y^PI. (1994) Immunization with anticardiolipin cofactor (beta-2-glycoprotein I) induces experimental antiphospholipid syndrome in naive mice. J Autoimmun 7(4):441-455.  2.491;  53/115;  126;  123

28.              Blank M^C, Manosroi J^C, Tomer Y^C, Manosroi A^C, Kopolovic J^C, Charcon-Polak S^C, and Shoenfeld Y^PI. (1994) Suppression of experimental systemic lupus erythematosus (SLE) with specific anti-idiotypic antibody-saporin conjugate. Clin Exp Immunol 98(3):434-441. 2.805;  46/115;  20;  19

29.              Gurevitz O^PI, Goldschmied-Reuven A^C, Block C^C, Kopolovic J^C, Farfel Z^C and Hassin D^PI. (1994) Cryptococcus neoformans vertebral mmunohistoche. J Med Vet Mycol 32(4):315-318.   x;  x;  4;  4

30.              Blank M^PI, Krause I^C, Buskila D^C, Teitelbaum D^C, Kopolovic J^C, Afek A^C, Goldberg I^C, and Shoenfeld Y^PI. (1995) Bromocriptine mmunohistochemi of experimental SLE and primary antiphospholipid syndrome via induction of nonspecific T suppressor cells. Cell Immunol 162(1):114-122.  1.588;  115/153;  85/115;  43;  43

31.              Blank M^PI, Tomer Y^C, Stein M^C, Kopolovic J^C, Wiik A^C, Meroni PL^C, Conforti G^C, and Shoenfeld Y^PI. (1995) Immunization with anti-neutrophil cytoplasmic antibody (ANCA) induces the production of mouse ANCA and perivascular lymphocyte infiltration. Clin Exp Immunol 102(1):120-130.  2.805;  46/115;  57;  57

32.              Friedlaender M^PI, Popovtzer MM^C, Weiss O^C, Nefesh I^C, Kopolovic J^PI, and Raz I^PI. (1995) Insulin-like growth factor-1 (IGF-1) enhances recovery from HgCl2-induced acute renal failure: the effects on renal IGF-1, IGF-1 receptor, and IGF-binding protein-1 mRNA. J Am Soc Nephrol 5(10):1782-1791.  7.240;  1/51;  33;  33

33.              Shoenfeld Y^PI, Gilburd B^C, Hojnik M^C, Damianovich M^C, Hacham S^C, Kopolovic Y^C, Polak-Charcon P^C Goldberg I^C, Afek A^C, and Hun-Chi L^PI. (1995) Induction of Goodpasture antibodies to noncollagenous domain (NC1) of type IV collagen in mice by idiotypic manipulation. Hum Antibod Hybridomas 6(4):122-128.  x;  x;  6;  6

34.              Krause I^PI, Blank M^C, Kopolovic J^PI, Afek A^C, Goldberg I^C, Tomer Y^C, and Shoenfeld Y^PI. (1995) Abrogation of experimental systemic lupus erythematosus and primary antiphospholipid syndrome with intravenous gamma globulin. J Rheumatol 22(6):1068-1074. 3.010;  8/12;  56;  54

35.              Oren R^PI, Laufer J^C, Goldberg I^C, Kopolovic J^C Waldherr R^C and Passwell JH^PI. (1995) C3, C4, factor B and HLA-DR alpha mRNA expression in renal biopsy specimens from patients with IgA nephropathy. Immunology 86(4):575-583.  3.507;  31/115;  17;  16

36.              Davidson B^PI, and Kopolovic J^PI. (1995) Molecular biology of human papilloma virus infection of the female genital tract. Harefuah 129(10):417-420 [Hebrew].  x;  x;  0

37.              Barzilai A^PI, Goldberg I^C, Shibi R^C, Kopolovic J^PI, and Trau H^PI. (1996) Mycosis fungoides expressing gamma/delta T-cell receptors. J Am Acad Dermatol 34(2 Pt 1):301-302.  2.402;  5/39;  9;  9

38.              Kopolovic J^PI and Wolman M^PI. (1996) Reasons underlying discrepancies in results between immunohistochemistry and molecular biology. Eur J Histochem 40(3):177-180. 0.990;  131/153;  3;  3

39.              Kanety H^PI, Kattan M^C, Goldberg I^C, Kopolovic J^C, Ravia J^C, Menczer J^C, and Karasik A^PI. (1996) Increased insulin-like growth factor binding protein-2 (IGFBP-2) gene expression and protein production lead to high IGFBP-2 content in malignant ovarian cyst fluid. Br J Cancer 73(9):1069-1073.  4.115;  32/123;  29;  29

40.              Ziporen L^PI, Goldberg I^C, Arad M^C, Hojnik M^C Ordi-Ros J^C, Afek A^C, Blank M^C, Sandbank Y^C, Vilardell-Tarres M^C, de Torres I^PI, Weinberger A^C, Asherson RA^C, Kopolovic Y^PI, and Shoenfeld Y^PI. (1996) Libman-Sacks endocarditis in the antiphospholipid syndrome: immunopathologic findings in deformed heart valves. Lupus 5(3):196-205.  2.400;  10/22;  46;  44

41.              Damianovich M^PI, Gilburd B^C, George J^C, Del Papa N^C, Afek A^C, Goldberg I^C, Kopolovic Y^PI, Roth D^C, Barkai G^C, Meroni PL^C, and Shoenfeld Y^PI. (1996) Pathogenic role of anti-endothelial cell antibodies in mmunohist. An idiotypic experimental model. J Immunol 156(12):4946-4951.           6.387;  12/115;  60;  60

42.              Orenstein A^PI, Kostenich G^C, Roitman L^C, Shechtman Y^C, Kopolovic Y^C, Ehrenberg B^C, and Malik Z^PI. (1996) A comparative study of tissue distribution and photodynamic therapy selectivity of mmunohi e6, Photofrin II and ALA-induced protoporphyrin IX in a colon carcinoma model. Br J Cancer 73(8):937-944.  4.115;   32/123;  34;  34

43.              Orenstein A^PI, Klein D^C, Kopolovic J^C, Winkler E^C, Malik Z^C, Keller N^C, and Nitzan Y^PI. (1997) The use of porphyrins for eradication of Staphylococcus aureus in burn wound infections. FEMS Immunol Med Microbiol 19(4):307-314. 2.371;  56/115;  22/43;  7;  7

44.              Davidson B^PI, Goldberg I^PI, and Kopolovic J^PI. (1997) Angiogenesis in uterine cervical intraepithelial neoplasia and squamous cell carcinoma: an mmunohistochemical study. Int J Gynecol Pathol 16(4):335-338.  1.817;  57/96;  31/66;  13;  12

45.              Davidson B^PI, Goldberg I^PI, and Kopolovic J^PI. (1997) Inflammatory response in cervical intraepithelial neoplasia and squamous cell carcinoma of the uterine cervix. Pathol Res Pract 193(7):491-495.  1.049;  45/66;  11;  10

46.              Finkelstein Y^PI, Malik Z^C, Kopolovic J^PI, Bernheim J^C, Djaldetti M^C, and Ophir D^PI. (1997) Characterization of smoking-induced nasopharyngeal lymphoid hyperplasia. Laryngoscope 107(12 Pt 1):1635-1642.  1.617;  43/72;  6/29;  6;  6

47.              George J^PI, Afek A^C, Gilburd B^C, Levy Y^C, Blank M^C, Kopolovic J^C, Harats D^C, and Shoenfeld Y^PI. (1997) Atherosclerosis in LDL-receptor knockout mice is accelerated by immunization with anticardiolipin antibodies. Lupus 6(9):723-729.         2.411;  10/22;  54;  53

48.              Inbal B^PI, Cohen O^C, Polak-Charcon S^C, Kopolovic J^C, Vadai E^C Eisenbach L^C, and Kimchi A^PI. (1997) DAP kinase links the control of apoptosis to metastasis. Nature 390(6656):180-184.  29.273;  2/48;  160;  160

49.              Talmi YP^PI, Liokumovitch P^C, Wolf M^C, Horowitz Z^C, Kopolovitch J^PI, and Kronenberg J^PI. (1997) Anatomy of the postauricular island “revolving door” flap (“flip-flop” flap). Ann Plast Surg 39(6):603-607.  0.906;  78/139;  3;  3

50.              Afek A^PI, Shibi R^PI, and Kopolovic J^PI. (1997) Benign and premalignant breast lesions—clinico-pathological correlation. Harefuah 133(9):375-378 [Hebrew].  x;  x;  0

51.              Amital H^PI, Levi Y^C, Blank M^C, Barak V^C, Langevitz P^C, Afek^C A, Nicoletti F^C, Kopolovic J^C, Gilburd B^C, Meroni PL^C, and Shoenfeld Y^PI. (1998) Immunomodulation of murine experimental SLE-like disease by interferon-gamma. Lupus 7(7):445-454. 2.411;  10/22;  8;  8

52.              Barshack I^PI, Goldberg I^C, Davidson B^C, Ravid A^C, Schiby G^C, Kopolovic J^C, Leviav A^C, and Friedman E^PI. (1998) Expression of rasGTPase activating protein in basal cell carcinoma of the skin. Mod Pathol 11(3):271-275.  x;  x;  4;  4

53.              Barshack I^PI, Goldberg I^C, Nass D^C, Olchovsky D^C, and Kopolovic J^PI. (1998) CD44 expression in normal adrenal tissue and adrenal tumours. J Clin Pathol 51(1):52-54.  2.170;  22/66;  4;  4

54.              Barzilai A^PI, Goldberg I^C, Yulash M^C, Pavlotsky F^C, Zuckerman A^C, Trau H^C, Azizi E^C, and Kopolovic J^PI. (1998) Silver-stained nucleolar organizer regions (AgNORs) as a prognostic value in malignant melanoma. Am J Dermatopathol 20(5):473-477.  1.377;  18/39;  11;  11

55.              Rothmann C^PI, Barshack I^C, Kopolovic J^PI, and Malik Z^PI. (1998) Spectrally resolved morphometry of the nucleus in hepatocytes stained by four histological methods. Histochem J 30(8):539-547.  1.397;  89/139;  5;  4

56.              George J^PI, Afek A^C, Gilburd B^C, Blank M^C, Levy Y^C, Aron-Maor A^C, Levkovitz H^C, Shaish A^C, Goldberg I^C, Kopolovic J^PI, Harats D^C, and Shoenfeld Y^PI. (1998) Induction of early atherosclerosis in LDL-receptor-deficient mice immunized with beta2-glycoprotein I. Circulation 98(11):1108-1115.  11.632;  1/72;  1/60;  1/51;  83;  78

57.              Goldberg I^PI, Davidson B^C, Lerner-Geva L^C, Gotlieb WH^C, Ben-Baruch G^C Novikov I^C, and Kopolovic J^PI. (1998) Expression of extracellular matrix proteins in cervical squamous cell carcinoma—a clinicopathological study. J Clin Pathol 51(10):781-785. 2,170;  22/66;  6;  5

58.              Levy Y^PI, Afek A^C, Sherer Y^C, Bar-Dayan Y^C, Shibi R^C, Kopolovic J^C, and Shoenfeld Y^PI. (1998) Malignant thymoma associated with autoimmune diseases: a retrospective study and review of the literature. Semin Arthritis Rheum 28(2):73-79.  3.580;  6/22;  11;  11

59.              Davidson B^PI, Agulansky L^C, Goldberg I^C, Friedman E^C, Ramon J^C, Barshack I^C, and Kopolovic J^PI. (1998) Immunohistochemical analysis of rasGTPase activating protein (rasGAP) in prostate cancer. Pathol Res Pract 194(6):399-404.  1.049;  45/66;  2;  2

60.              Davidson B^PI, Goldberg I^C, Gotlieb WH^C, Ben-Baruch G^C, and Kopolovic J^PI. (1998) Expression of matrix proteins in uterine cervical neoplasia using immunohistochemistry. Eur J Obstet Gynecol Reprod Biol 76(1):109-114. 1.141;  34/57;  21/24;  4;  4

61.              Davidson B^PI, Goldberg I^C, Gotlieb WH^C, Ben-Baruch G^C, and Kopolovic J^PI (1998) CD44 expression in uterine cervical intraepithelial neoplasia and squamous cell carcinoma: an mmunohistochemical study. Eur J Gynaecol Oncol 19(1):46-49. 0.591;  121/123;  55/57;  4;  4

62.              Davidson B^PI, Goldberg I^C, Gotlieb WH^C, Lerner-Geva L^C, Ben-Baruch G^C, and Kopolovic J^PI. (1998) Ulex Europaeus lectin and anti-CD31 staining in squamous cell carcinoma of the uterine cervix: potential prognostic markers. Int J Gynecol Pathol 17(3):205-210.  1.817;  19/57;  31/66;  3;  3

63.              Davidson B^PI, Goldberg I^C, Liokumovich P^C, Kopolovic J^PI, Gotlieb WH^C, Lerner-Geva L^C, Reder I^C, Ben-Baruch G^C, and Reich R^PI. (1998) Expression of metalloproteinases and their inhibitors in adenocarcinoma of the uterine cervix. Int J Gynecol Pathol 17(4):295-301.  1.817;  19/57;  31/66;  2;  2

64.              Gotlieb WH^PI, Flikker S^C, Davidson B^C, Korach Y^C, Kopolovic J^PIand Ben-Baruch G^PI. (1998) Borderline tumors of the ovary: fertility treatment, conservative management, and pregnancy outcome. Cancer 82(1):141-146.            4.800; 21/123;  48;  45

65.              Gotlieb WH^PI, Friedman E^C, Bar-Sade RB^C, Kruglikova A^C, Hirsh-Yechezkel G^C, Modan B^C, Inbar M^C, Davidson B^C, Kopolovic J^C, Novikov I^C, and Ben-Baruch G^PI. (1998) Rates of Jewish ancestral mutations in BRCA1 and BRCA2 in borderline ovarian tumors. J Natl Cancer Inst 90(13):995-1000. 15.171;  4/123;  28;  28

66.              Afek A^PI, George J^C, Shoenfeld Y^C, Gilburd B^C, Levy Y^C, Shaish A^C, Keren P^C, Janackovic Z^C, Goldberg I^C, Kopolovic J^PI, and Harats D^PI. (1999) Enhancement of atherosclerosis in beta-2-glycoprotein I-immunized apolipoprotein E-deficient mice. Pathobiology 67(1):19-25.  1.511;  117/153;  35/66;  34;  33

67.              Afek A^PI, Shoenfeld Y^C, Manor R^C, Goldberg ^CI, Ziporen L^C, George J^C, Polak-Charcon S^C, Amigo MC^C, Garcia-Torres R^C, Segal R^C, and Kopolovic J^PI. (1999) Increased endothelial cell expression of alpha3beta1 integrin in cardiac valvulopathy in the primary (Hughes) and secondary antiphospholipid syndrome. Lupus 8(7):502-507.  2.400;  10/22;  19;  18

68.              Bar-Dayan Y^PI, Afek A^C, Bar-Dayan Y^C, Goldberg I^C, and Kopolovic J^PI. (1999) Proliferation, apoptosis, and thymic involution. Tissue Cell 31(4):391-396.  1.132;  11/15;  125/153;  10;  10

69.              Bar-Dayan Y^PI, Barshack I^C, Blank M^C, Goldberg I^C, Levy Y^C, Kopolovic J^C, Fishman P^C, and Shoenfeld Y^PI. (1999) Antibodies to the cytoplasm, cell membrane and nuclear membrane of malignant neoplasms in pooled normal human polyspecific immunoglobulin G. Int J Oncol 15(6):1091-1096.          2.681;  55/123;  10;  10

70.              Bahar M^PI, Cohen ML^C, Grinshpoon Y^C, Kopolovic U^C, Herbert M^C, Nass D^C, and Chanimov M^PI. (1998) An investigation of the possible neurotoxic effects of intrathecal midazolam combined with fentanyl in the rat. Eur J Anaesthesiol 15(6):695-701.  1.126;  13/22;  7;  7

71.              George J^PI, Afek A^C, Gilburd B^C, Levkovitz H^C, Shaish A^C, Goldberg I^C, Kopolovic Y^C, Wick G^C, Shoenfeld Y^C, and Harats D^PI. (1998) Hyperimmunization of apo-E-deficient mice with homologous malondialdehyde low-density lipoprotein suppresses early atherogenesis. Atherosclerosis 138(1):147-152.  3.777;  11/151;  94;  90

72.              Barshack I^PI, Kopolovic J^PI, Malik Z^C, and Rothmann C^PI. (1999) Spectral morphometric characterization of breast carcinoma cells. Br J Cancer 79(9-10):1613-1619. 4.115;  32/123;  5;  5

73.              Davidson B^PI, Goldberg I^C, Gotlieb WH^C, Kopolovic J^C, Ben-Baruch G^C, Nesland JM^C, Berner A^C, Bryne M^C, and Reich R^PI. (1999) High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma. Clin Exp Metastasis 17(10):799-808  2.811;  54/123;  65;  54

74.              Davidson B^PI, Goldberg I^C, Gotlieb WH^C, Lerner-Geva L^C, Ben-Baruch G^C, Agulansky L^C, Novikov I^C, and Kopolovic J^PI. (1999) Macrophage infiltration and angiogenesis in cervical squamous cell carcinoma—clinicopathologic correlation. Acta Obstet Gynecol Scand 78(3):240-244.  1.548;  27/57;  14;  14

75.              Davidson B^PI, Goldberg I^C, Kopolovic J^PI Lerner-Geva L^C, Gotlieb WH^C, Ben-Baruch G^PI, and Reich R^PI. (1999) MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma—a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization. Gynecol Oncol 73(3):372-382.  2.251;  67/123;  12/57;  52;  46

76.              Davidson B^PI, Goldberg I^C, Kopolovic J^PI, Lerner-Geva L^C, Gotlieb WH^C, Weis B^C, Ben-Baruch G^PI, and Reich R^PI. (1999) Expression of matrix metalloproteinase-9 in squamous cell carcinoma of the uterine cervix-clinicopathologic study using immunohistochemistry and mRNA in situ hybridization. Gynecol Oncol 72(3):380-386.  2.251;  67/123;  12/57;  28;  27

77.              George J^PI, Harats D^C, Gilburd B^C, Afek A^C, Levy Y^C, Schneiderman J^C, Barshack I^C, Kopolovic J^PI, and Shoenfeld Y^PI. (1999) Immunolocalization of beta2-glycoprotein I (apolipoprotein H) to human atherosclerotic plaques: potential implications for lesion progression. Circulation 99(17):2227-2230.  11.632;  1/72;  1/60;  1/51;  68;  68

78.              George J^PI, Shoenfeld Y^C, Afek A^C, Gilburd B^C, Keren P^C, Shaish A^C, Kopolovic J^PI, Wick G^C, and Harats D. ^PI (1999) Enhanced fatty streak formation in C57BL/6J mice by immunization with heat shock protein-65. Arterioscler Thromb Vasc Biol 19(3):505-510. 7.053;  4/60;  4/51;  87;  85

79.              Laufer J^PI, Oren R^C, Goldberg I^C, Afek A^C, Kopolovic J^PI, and Passwell JH^C. (1999) Local complement genes expression in the mammary gland: effect of gestation and inflammation. Pediatr Res 46(5):608-612.  2.875;  6/73;  3;  3

80.              Liokumovich P^PI, Goldberg I^C, Davidson B^C, Gotlieb WH^C, Zahavi T^C, Ben-Baruch G^C, Reder I^C, and Kopolovic J^PI. (1999) Expression of metalloproteinases endometrial stromal sarcoma: mmunohistochemical study using image analysis. J Clin Pathol 52(3):198-202.  2.170;  22/66;  12;  12

81.              Afek A^PI, George J^C, Gilburd B^C, Rauova L^C, Goldberg I^C, Kopolovic J^PI, Harats D^C and Shoenfeld Y^PI. (2000) Immunization of low-density lipoprotein receptor deficient (LDL-RD) mice with heat shock protein 65 (HSP-65) promotes early atherosclerosis. J Autoimmun 14(2):115-121.  2.491;  53/115;  42;  42

82.              Barzilai A^PI, Langevitz P^C, Goldberg I^C, Kopolovic J^C, Livneh A^C, Pras M^C, and Trau H^PI. (2000) Erysipelas-like erythema of familial Mediterranean fever: clinicopathologic correlation. J Am Acad Dermatol 42(5 Pt 1):791-795.  2.402;  5/39;  7;  7

83.              Davidson B^PI, Goldberg I^C, Kopolovic J^PI, Gotlieb WH^C, Givant-Horwitz V^C, Nesland JM^C, Berner A^C, Ben-Baruch G^C, Bryne M^C, and Reich R^C. (2000) Expression of angiogenesis-related genes in ovarian carcinoma—a clinicopathologic study. Clin Exp Metastasis 18(6):501-507.  2.811;  54/123;  8;  6

84.              Davidson B^PI, Goldberg I^C, Lerner-Geva L^C, Gotlieb WH^C, Ben-Baruch G^C, Novikov I^C and Kopolovic J^PI. (2000) Expression of topoisomerase II and Ki-67 in cervical carcinoma—clinicopathological study using immunohistochemistry. APMIS 108(3):209-215.  2.127;  65/115;  48/86;  23/66;  13;  13

85.              Davidson B^PI, Gotlieb WH^C, Ben-Baruch G^C, Kopolovic J^PI, Goldberg I, ^C Nesland JM^C, Berner A^C, Bjamer A^C, and Bryne M^PI. (2000) Expression of carbohydrate antigens in advanced-stage ovarian carcinomas and their metastases-A clinicopathologic study. Gynecol Oncol 77(1):35-43.   2.251;  67/123;  12/57;  19;  12

86.              Davidson B^PI, Gotlieb WH^C, Ben-Baruch G^C, Nesland JM^C, Bryne M^C, Goldberg I^C, Kopolovic J^PI, and Berner A^PI. (2000) E-Cadherin complex protein expression and survival in ovarian carcinoma. Gynecol Oncol 79(3):362-371.  2.251;   67/123;  12/57;  17;  11

87.              Ferber S^PI, Halkin A^C, Cohen H^C, Ber I^C, Einav Y^C, Goldberg I^C, Barshack I^C, Seijffers R^C, Kopolovic J^C, Kaiser N^C, and Karasik A^PI. (2000) Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat Med 6(5):568-572.  28.878;  3/261;  3/153;  1/72;  187;  187

88.              George J^PI, Harats D^C, Gilburd B^C, Afek A^C, Shaish A^C, Kopolovic J^PI, and Shoenfeld Y^PI. (2000) Adoptive transfer of beta(2)-glycoprotein I-reactive lymphocytes enhances early atherosclerosis in LDL receptor-deficient mice. Circulation 102(15):1822-1827.  11.632;  1/72;  1/60;  1/51;  47;  47

89.              Gotlieb WH^PI, Soriano D^C, Achiron R^C, Zalel Y^C, Davidson B^C, Kopolovic J^C, Novikov I^C, and Ben-Baruch G^PI. (2000) CA 125 measurement and ultrasonography in borderline tumors of the ovary. Am J Obstet Gynecol 183(3):541-546.  3.083;  7/57;  8;  8

90.              Keren P^PI, George J^C, Shaish A^C, Levkovitz H^C, Janakovic Z^C, Afek A^C, Goldberg I^C, Kopolovic J^C, Keren G^C, and Harats D^PI. (2000) Effect of hyperglycemia and hyperlipidemia on atherosclerosis in LDL receptor-deficient mice: establishment of a combined model and association with heat shock protein 65 immunity. Diabetes 49(6):1064-1069.  8.028;  3/89;  17;  17

91.              Laufer J^C, Oren R^C, Goldberg I^C, Horwitz A^C, Kopolovic J^C, Chowers Y^C, and Passwell JH^PI. (2000) Cellular localization of complement C3 and C4 transcripts in intestinal specimens from patients with Crohn’s disease. Clin Exp Immunol 120(1):30-37.  2.805;  46/115;  8;  8

92.              Lavon I^PI, Goldberg I^C, Amit S^C, Landsman L^C, Jung S^C, Tsuberi BZ^C, Barshack I^C, Kopolovic J^C, Galun E^C, Bujard H^C, and Ben-Neriah Y^C. (2000) High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for mmunohisto NF-kappaB activation. Nat Med 6(5):573-577.  28.878;  3/261;  3/153;  1/72;  59;  59

93.              Meyerovitch J^C, Waner T^C, Sack J^C, Kopolovic J^PI, and Shemer J^PI. (2000) Attempt to prevent the development of diabetes in non-obese diabetic mice by oral vanadate administration. Isr Med Assoc J 2(3):211-214.  0.456;  62/110;  2;  2

94.              Ravid A^PI, Barshack I^C, Hirsh-Yechezkel G^C, Goldberg I^C, Bar-Sade RB^C, Chetrit A^C, Reder I^C, Ben-Baruch G^C, Gotlieb WH^C, Kopolovic J^PI, and Friedman E^PI. (2000) Immunohistochemical analyses of sporadic and familial (185delAG carriers) ovarian cancer in Israel. Eur J Cancer 36(9):1120-1124.  3.706;  38/123;  3;  2

95.              Rothmann C^PI, Barshack I^C, Gil A^C, Goldberg I^C, Kopolovic J^PI, and Malik Z^PI. (2000) Potential use of spectral image analysis for the quantitative evaluation of estrogen receptors in breast cancer. Histol Histopathol 15(4):1051-1057.  2.023;  98/153;  27/66;  3;  3

96.              Barshack I^PI, Goldberg I^C, Chowers Y^C, Weiss B^C, Horowitz A^C, and Kopolovic J^PI. (2001) Immunohistochemical analysis of candidate gene product expression in the duodenal epithelium of children with mmuno sprue. J Clin Pathol 54(9):684-688.  2.170;  22/66;  4;  4

97.              Beiner ME^PI, Gotlieb WH^C, Davidson B^C, Kopolovic J^PI, and Ben-Baruch G^PI. (2001) Infertility treatment after conservative management of borderline ovarian tumors. Cancer 92(2):320-325.  4.800;  21/123;  11;  11

98.              Cohen B^PI, Barkan D^C, Levy Y^C, Goldberg I^C Fridman E^C, Kopolovic J^PI, and Rubinstein M^PI. (2001) Leptin induces angiopoietin-2 expression in adipose tissues. J Biol Chem 276(11):7697-7700.  5.854;  38/261;  34;  34

99.              Davidson B^PI, Goldberg I^C, Berner A^C, Nesland JM^C Givant-Horwitz V^C, Bryne M^C, Risberg B^C, Kristensen GB^C, Trope CG^C, Kopolovic J^PI, and Reich R^PI. (2001) Expression of membrane-type 1, 2, and 3 matrix metalloproteinases messenger RNA in ovarian carcinoma cells in serous effusions. Am J Clin Pathol 115(4):517-524.     2.942;  12/66;  25;  25

100.          Davidson B^PI, Nesland JM^C, Goldberg I^C, Kopolovic J^PI, Gotlieb WH^C, Bryne M^C, Ben-Baruch G^C, Berner A^C, and Reich R^PI. (2001) Caveolin-1 expression in advanced-stage ovarian carcinoma—a clinicopathologic study. Gynecol Oncol 81(2):166-171.  2.251;  67/123;  12/57;  18;  18

101.          Davidson B^PI, Reich R^C, Berner A^C, Givant-Horwitz V^C, Goldberg I^C, Risberg B^C, Kristensen GB^C, Trope CG^C, Bryne M^C, Kopolovic J^PI, and Nesland JM^PI. (2001) Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels. Eur J Cancer 37(16):2040-2049.  3.706;  38/123;  30;  26

102.          Davidson B^PI, Reich R^C, Goldberg I^C, Gotlieb WH^C, Kopolovic J^C, Berner A^C, Ben-Baruch G^C, Bryne M^C, and Nesland JM^PI. (2001) Ets-1 messenger RNA expression is a novel marker of poor survival in ovarian carcinoma. Clin Cancer Res 7(3):551-557.  5.715;  15/123;  33;  33

103.          Goldberg I^PI, Davidson B^C, Reich R^C, Gotlieb WH^C, Ben-Baruch G^C, Bryne M^C, Berner A^C, Nesland JM^C, and Kopolovic J^PI. (2001) Alpha V integrin expression is a novel marker of poor prognosis in advanced-stage ovarian carcinoma. Clin Cancer Res 7(12):4073-4079. 5.715;  15/123;  0

104.          Gotlieb WH^PI, Goldberg I^C, Weisz B^C, Davidson B^C, Novikov I^C, Kopolovic J^PI, and Ben-Baruch G^PI. (2001) Topoisomerase II immunostaining as a prognostic marker for survival in ovarian cancer. Gynecol Oncol 82(1):99-104.     2.251;  67/123;  12/57;  9;  8

105.          Auslender S^PI, Barzilai A^C, Goldberg I^C, Kopolovic J^PI, and Trau H^PI. (2002) Lentigo maligna and superficial spreading melanoma are different in their in situ phase: an mmunohistochemical study. Hum Pathol 33(10):1001-1005.  2.550;  18/66;  2;  2

106.          Barshack I^PI, Goldberg I^C, Chowers Y^C, Horowitz A^C, and Kopolovic J^PI (2002) Different beta-catenin immunoexpression in carcinoid tumors of the appendix in comparison to other gastrointestinal carcinoid tumors. Pathol Res Pract 198(8):531-536.         1.049;  45/66;  6;  6

107.          Blank M^PI, Krause I^C, Fridkin M^C, Keller N^C, Kopolovic J^C, Goldberg I^C, Tobar A^C and Shoenfeld Y^PI. (2002) Bacterial induction of autoantibodies to beta2-glycoprotein-I accounts for the infectious etiology of antiphospholipid syndrome. J Clin Invest 109(6):797-804.  15.053;  2/72;  82;  82

108.          Davidson B^C, Goldberg I^C, Givant-Horwitz V^C, Nesland JM^C, Berner A^C, Bryne M^C, Risberg B^C, Kopolovic J^PI, Kristensen GB^C, Trope CG^C, van de Putte G^C, and Reich R^PI. (2002) Caveolin-1 expression in ovarian carcinoma is MDR1 independent. Am J Clin Pathol 117(2):225-234.  2.942;  12/66;  8;  7

109.          Davidson B^PI, Goldberg I^C, Gotlieb WH^C, Kopolovic J^PI, Ben-Baruch G^C, Nesland JM^C, and Reich R^PI. (2002) The prognostic value of metalloproteinases and angiogenic factors in ovarian carcinoma. Mol Cell Endocrinol 187(1-2):39-45.  2.786;  67/153;  35/89;  21;  21

110.          Davidson B^PI, Reich R^PI, Kopolovic J^PI, Berner A^C, Nesland JM^C, Kristensen GB^C, Trope CG^C, Bryne M^C, Risberg B^C, van de Putte G^C, and Goldberg I^PI. (2002) Interleukin-8 and vascular endothelial growth factor mRNA and protein levels are down-regulated in ovarian carcinoma cells in serous effusions. Clin Exp Metastasis 19(2):135-144.  2.811;  54/123;  23;  21

111.          Grunebaum E^PI, Blank M^C, Cohen S^C, Afek A^C, Kopolovic J^C, Meroni PL^C, Youinou P^C, and Shoenfeld Y^PI. (2002) The role of anti-endothelial cell antibodies in Kawasaki disease — in vitro and in vivo studies. Clin Exp Immunol 130(2):233-240. 2.805;  46/115;  11;  11

112.          Shoenfeld Y^PI, Rauova L^C, Gilburd B^C, Kvapil F^C, Goldberg I^C, Kopolovic J^C, Rovensky J^C, and Blank M^PI. (2002) Efficacy of IVIG affinity-purified anti-double-stranded DNA anti-idiotypic antibodies in the treatment of an experimental murine model of systemic lupus erythematosus. Int Immunol 14(11):1303-1311.  3.317;  34/115;  22;  22

113.          Barshack I^PI, Keren P^C, Goldberg I^C, Kopolovic J^C, Keren G^C, and George J^PI (2003) Relation of preexisting anti-beta2GPI antibodies to infarct size in a rat model. Cardiovasc Pathol 12(4):195-201.  1.706;  33/72;  32/66;  1;  1

114.          Davidson B^PI, Goldberg I^C, Gotlieb WH^C, Kopolovic J^PI, Ben-Baruch G^PI, and Reich R^PI. (2003) PEA3 is the second Ets family transcription factor involved in tumor progression in ovarian carcinoma. Clin Cancer Res 9(4):1412-1419. 5.715;  15/123;  13;  12

115.          Davidson B^PI, Goldberg I^C, Reich R^C, Tell L^C, Dong HP^C, Trope CG^C, Risberg B^C, and Kopolovic J^PI. (2003) Alpha V- and beta1-integrin subunits are commonly expressed in malignant effusions from ovarian carcinoma patients. Gynecol Oncol 90(2):248-257. 2.251;  67/123;  12/57;  14;  13

116.          Barshack I^PI, Fridman E^C, Goldberg I^C, Chowers Y^C, and Kopolovic J^PI. (2004) The loss of calretinin expression indicates aganglionosis in Hirschsprung’s disease. J Clin Pathol 57(7):712-716.  2.170;  22/66;  1;  1

117.          Barshack I^PI Kopolovic J^PI, Chowers Y^C, Gileadi O^C, Vainshtein A^C, Zik O^C, and Behar V^PI. (2004) A novel method for “Wet” SEM. Ultrastruct Pathol 28(1):29-31.  0.809;  7/9;  57/66;  3;  3

118.          Barshack I^PI, Polak-Charcon S^C, Behar V^C, Vainshtein A^C, Zik O^C, Ofek E^C Hadani M^C, Kopolovic J^PI, and Nass D^PI. (2004) Wet SEM: a novel method for rapid diagnosis of brain tumors. Ultrastruct Pathol 28(4):255-260.  0.809;  7/9;  57/66;  2: 2

119.          Blank M^PI, Shani A^C, Goldberg I^C, Kopolovic J^C, Amigo MC^C, Magrini L^C, and Shoenfeld Y^PI. (2004) Libman-Sacks endocarditis associated with antiphospholipid syndrome and infection. Thromb Res 114(5-6):589-592.  2.012;  30/60;  29/51;  6;  6

120.          Bruchim I^PI, Fishman A^C, Friedman E^C, Goldberg I^C, Chetrit A^C, Barshack I^C, Dekel E^C, Hirsh-Yechezkel G^C, Modan B^C, and Kopolovic J^PI. (2004) Analyses of p53 expression pattern and BRCA mutations in patients with double primary breast and ovarian cancer. Int J Gynecol Cancer 14(2):251-258.  1.427;  96/123;  0

121.          Davidson B^PI, Goldberg I^C, Tell L^C, Vigdorchik S^C, Baekelandt M^C, Berner A^C Kristensen GB^C, Reich R^PI, and Kopolovic J^PI. (2004) The clinical role of the PEA3 transcription factor in ovarian and breast carcinoma in effusions. Clin Exp Metastasis 21(3):191-199.  2.811;  54/123;  6;  6

122.          Koukoui L^PI, Blau A^C, Kopolovic J^PI, Pras M^C, and Livneh A^PI. (2004) A possible favorable effect of mmunohisto in IgA nephropathy in a carrier of a MEFV mutation. Clin Nephrol 62(3):226-228.  1.543  26/51;  1;  1

123.          Ziporen L^PI, Polak-Charcon S^C, Korczyn DA^C, Goldberg I^C, Afek A^C, Kopolovic J^C, Chapman J^C, and Shoenfeld Y^PI. (2004) Neurological dysfunction associated with antiphospholipid syndrome: histopathological brain findings of mmunohist changes in a mouse model. Clin Dev Immunol 11(1):67-75.   x;  x;  4;  4

124.          Fridman E^PI, Pinthus JH^C, Kopolovic J^C, Ramon J^C, Mor O^C, and Mor Y^PI. (2006) Expression of cyclooxygenase-2 in Wilms tumor: mmunohistochemical study using tissue microarray methodology. J Urol 176(4 Pt 2):1747-1750.  3.592;  7/51;  x

125.          Odegaard E^PI, Staff AC^C, Abeler VM^C, Kopolovic J^C, Onsrud M^C, Lazarovici P^C, and Davidson B^PI. (2006) The activated nerve growth factor receptor p-TrkA is selectively expressed in advanced-stage ovarian carcinoma. Hum Pathol.   2.550;  18/66;  x

126.          Odegaard E^PI, Staff AC^C, Kaern J^C, Florenes VA^C, Kopolovic J^C, Trope CG^C, Abeler VM^C, Reich R^C, and Davidson B^PI. (2006) The AP-2gamma transcription factor is upregulated in advanced-stage ovarian carcinoma. Gynecol Oncol 100(3):462-468.    2.251;  67/123;  12/57;  x

Case Reports

1.      Porat S^PI, Brezis M^C, and Kopolovic J^PI. (1977) Salmonella typhi mmunohistoche long after a fracture: a case report. J Bone Joint Surg Am 59(5):687-689.  2.339; 4/41;  29/129;  15;  15

2.      Perl A^PI, Kopolovic J^PI, Ron N^C, and Perelman M^PI. (1977) Congenital atresia of trachea. Harefuah 93:245-246 [Hebrew].  x;  x;  2;  2

3.      Weshler Z^PI, Leviatan A^C, Gordon R^C, and Kopolovic J^PI. (1978) Development of Hodgkin’s disease in a patient with leprosy. Oncology 35(6):281-284.  1.985;  72/123;  1;  1

4.      Weshler Z^PI, Leviatan A^C, Krasnokuki D^C, and Kopolovitch J^PI. (1979) Primary Kaposi’s sarcoma in lymph nodes concurrent with chronic lymphatic leukemia. Am J Clin Pathol 71(2):234-237.            2.942;  12/66;  16;  16

5.      Blatt JM^PI, Kopolovic J^PI, Gimmon Z^C, and Rabinovici N^PI. (1979) Leiomyosarcoma of the rectum: diagnostic criteria and surgical approach. Int Surg 64(1):67-71.  0.432;  120/139;  6;  6

6.      Weshler Z^PI, Sulkes A^C, Kopolovitch J^PI, Leviatan A^C, and Shifrin E^PI. (1980) Bronchial malignant melanoma. J Surg Oncol 15(3):243-248.  1.779;  79/123;  38/38;  9;  9

7.      Freund U^PI, Kopolovic J^PI, and Durst AL^PI. (1980) Compressed air emboli of the aorta and renal artery in blast injury. Injury 12(1):37-38.  0.919;  13/18;  6/11;  77/139;  0

8.      Sulkes A^PI, Naparstek Y^C, Shalit M^C, and Kopolovic J^PI. (1980) Second primary lung carcinoma. J Surg Oncol 15(4):375-380.  1.779;  79/123;  38/38;  9;  9

9.      Cividalli G^PI, Yatziv S^C, Voss R^C, Galili U^C, Kopolovic J^C, Sagi M^C, Weizman Z^C, Brautbar C^C, and Kohn G^PI. (1981) XX/XY lymphoid mmunohis in a boy with fatal lymphohistiocytic proliferation. JAMA 246(17):1917-1920.  23.494;  3/105;  7;  7

10.  Gay I^PI, Elidan J^PI, and Kopolovic J^PI. (1981) Chondrosarcoma at the skull base. Ann Otol Rhinol Laryngol 90(1 Pt 1):53-55. 0.970;  13/29;  8;  8

11.  Sulkes A^PI, Weshler Z^PI, and Kopolovic Y^PI. (1982) Pericardial effusion as first evidence of malignancy in bronchogenic carcinoma. J Surg Oncol 20(2):71-74.  1.779;  79/123;  38/38;  9;  9

12.  Stalnikowitz R^PI, Sharon P^PI, and Kopolovic J^PI. (1982) Gastric xanthoma. Harefuah 102:518-519 [Hebrew].  x;  x;  0

13.  Rubinstein N^PI, Granat M^C, Kopolovic Y^PI, and Weinrauch L^PI. (1983) Esthiomene: report of a case in a young Israeli woman. Int J Dermatol 22(9):534-535.  0.942;  30/39;  1;  1

14.  Schlesinger M^PI, Kopolovic J^PI, Viskoper RJ^C, and Ron N^PI. (1983) A case of familial Mediterranean fever with cutaneous mmunohist and immune complex nephritis: light, electron, and immunofluorescent study of renal biopsy. Am J Clin Pathol 80(4):511-514.  2.942;  12/66;  16;  16

15.  Weshler Z^PI, Sulkes A^C, and Kopolovic J^PI. (1983) Squamous cell carcinoma of the renal pelvis as a late complication of hepatic irradiation: a case report. J Surg Oncol 22(2):84-86.  1.779;  79/123;  38/38;  2;  2

16.  Halpern J^PI, Kopolovic J^PI, and Catane R^PI. (1984) Malignant fibrous mmunohistoc developing in irradiated sacral mmunohi. Cancer 53(12):2661-2662.  4.800;  21/123;  39;  39

17.  Kopolovic J^PI, Rivkind A^PI, Rabinovici R^C, Klin B^C, and Eyal Z^PI. (1984) Amputation neuroma of common bile duct with obstructive jaundice: a case report. Appl Pathol 2(5):292-294.  x;  x;  0

18.  Kopolovic J^PI, Rivkind A^PI, and Sherman Y^PI (1984) Granulomatous prostatitis with mmunohist. A sequel to transurethral prostatic resection. Arch Pathol Lab Med 108(9):732-733.  1,587;  10/23;  44/72;  34/66;  15;  15

19.  Kopolovic J^PI, Okon E^PI, and Sadovsky E^PI (1984) A benign polyp of the vagina resembling sarcoma botryoides. J Obstet Gynecol 3:200-201.  4.170;  2/57;  0

20.  Pode D^PI, Kopolovic S^PI, and Gimmon Z^PI. (1984) Serum lactic dehydrogenase: a tumor marker of ovarian mmunohistoc in a female pseudohermaphrodite. Gynecol Oncol 19(1):110-113.  2.251;  67/123;  12/57;  7;  7

21.  Naparstek Y^PI, Kopolovic J^PI, Tur-Kaspa R^C, and Rubinger D^PI. (1984) Focal glomerulonephritis in the course of hydralazine-induced lupus syndrome. Arthritis Rheum 27(7):822-825.  x;  x;  18;  18

22.  Brauman A^PI, Gur H^C, Leibovitz A^C, Kopolovic J^C, Gilboa Y^C, and Eliakim M^PI. (1985) Primary fibroxanthosarcoma of the kidney presenting as fever of unknown origin. Eur Urol 11(2):134-135.  3.542;  8/51;  1;  1

23.  Rubinstein N^PI, Kopolovic J^C, Wexler MR^C, and Peled IJ^PI. (1985) Malignant blue nevus. J Dermatol Surg Oncol 11(9):921-923.  x;  x;  13;  13

24.  Kopolovic J^PI, and Oren R^PI. (1986) [IgM nephropathy – clinicopathological entity]. Harefuah 110(3):156-157.   x;  x;  0

25.  Lysy J^PI, Kopolovic J^PI, Polliack A^C, and Chowers I^PI. (1986) Myocardial telangiectases in hereditary hemorrhagic telangiectasia. Chest 89(3):472.  4.008;  3/33;  1;  1

26.  Friedlander MM^PI, Rubinger D^C, Ben-Chetrit E^C, and Kopolovic J^PI. (1986) IgA nephropathy and acute reversible renal failure. Isr J Med Sci 22:888-891 [Hebrew]. 0.456;  62/110;  2;  2

27.  Eliakim R^PI, Goldin E^C, Kopolovic J^PI, and Livshin R^PI. (1987) The esophagus in pemphigus vulgaris. Harefuah 112(4):170-171 [Hebrew].  x;  x;  3;  3

28.  Kopolovic J^PI, Weiss DB^C, Dolberg L^C, Brezinsky A^C, Ne’eman Z^C, and Anteby SO^PI. (1987) Alveolar soft-part sarcoma of the female genital tract. Case report with ultrastructural findings. Arch Gynecol 240(2):125-129.  x;  x;  4;  4

29.  Pe’er J^PI, Schwartzenberg T^PI, and Kopolovic J^PI. (1987) Granular cell tumor (myoblastoma) of the eyebrow. Ophthalmologica 194(1):1-4.  0.986;  29/44;  2;  2

30.              Friedlaender MM^PI, Kopolovic J^PI, Rubinger D^C, Silver J^C, Drukker A^C, Ben-Gershon Z^C, Durst AL^C, and Popovtzer MM^PI. (1987) Renal biopsy in Fabry’s disease eight years after successful renal transplantation. Clin Nephrol 27(4):206-211.  1.543;  26/51;  27;  27

31.              Ezra Y^PI, Fields S^C, Kopolovic J^C, and Anteby SO^PI. (1988) Benign uterine leiomyoma suspected of sarcomatous change on an ultrasound scan and computerized tomography. Arch Gynecol Obstet 241(4):255-258.            0.182;  52/53;  6;  6

32.  Kopolovic J^PI, Pinkus G^PI, and Rosen S^PI. (1988) Interstitial nephritis in infectious mononucleosis. Am J Kidney Dis 12(1):76-77.  4.412;  3/51;  20;  20

33.  Simon A^PI, Kopolovic J^PI, and Beyth Y^PI. (1988) Primary squamous cell carcinoma of the endometrium. Gynecol Oncol 31(3):454-461.  2.251;  67/123;  12/57;  11;  11

34.  Yinnon A^PI, Kopolovic J^PI, Dollberg L^C, and Hershko C^PI. (1988) Evolution of malignant lymphoma in agnogenic myeloid metaplasia. Oncology 45(5):373-377. 1.985;  72/123;  1;  1

35.  Golomb J^PI, Kopolovic J^PI, and Siegel Y^PI. (1992) Sclerosing lipogranuloma of the external male genitalia. Br J Urol 70(5):575.  1.242;  19/41;  5;  5

36.  Serour F^PI, Gilad A^C, Kopolovic J^PI, and Krispin M^PI. (1992) Secretory breast cancer in childhood and adolescence: report of a case and review of the literature. Med Pediatr Oncol 20(4):341-344.  1.649;  87/123;  19/73;  11;  11

37.  Schneider R^PI, Lugassy G^C, Schlesinger M^C, Kopolovic J^PI, and Yagil Y^PI. (1996) Fibrillar glomerulopathy associated with chronic lymphocytic leukaemia. Nephrol Dial Transplant 11(7):1352-1355.  2.976;  7/20;  10/51;  3;  3

38.  Barshack I^PI, Krupsky M^C, Perelman M^C, and Kopolovic J^PI. (1997) Pulmonary alveolar microlithiasis presenting with prolonged cough. Harefuah 132(11):748-750, 824 [Hebrew].  x;  x;  2;  2

39.  Barshack I^PI, Perelman M^C, Many A^C, Goshen E^C, Zwas ST^C, and Kopolovic J^PI. (1997) Littoral cell angioma: a vascular tumor mimicking a solid tumor on a Tc-99m-red blood cell spleen scan. Isr J Med Sci 33(10):677-680.  0.456;  62/110;  6;  6

40.  Afek A^PI, Kopolovic J^PI, and Shoenfeld Y^PI. (1998) Cytomegalovirus and atherosclerosis. Harefuah 134(11):869-871 [Hebrew].   x;  x;  0

41.  Barshack I^PI, and Kopolovic J^PI. (1998) Autopsy – its relevance in the modern era. Harefuah 134(10):807-809 [Hebrew].  x;  x;  0

42.  Da’as N^PI, Kleinman Y^C, Polliack A^C, Amir G^C, Ne’eman Z^C, Kopolovic J^PI, Bits H^C, and Darmon D^PI. (2001) Immunotactoid glomerulopathy with massive bone marrow deposits in a patient with IgM kappa monoclonal gammopathy and hypocomplementemia. Am J Kidney Dis 38(2):395-399.  4.412;  3/51;  2;  2

43.  Fridman E^PI, and Kopolovic J^PI. (2001) Metastatic breast tumor imitating primary colonic carcinoma. Isr Med Assoc J 3(7):551.  0.456;  62/110;  0

44.  Friedman E^PI, and Kopolovic J^PI. (2001) Renal cell carcinoma. Isr Med Assoc J 3(12):988, 989.  0.456;  62/110;  0

45.  Yosepovich A^PI, and Kopolovic J^PI. (2002) [Tissue microarray technology—a new and powerful tool for the molecular profiling of tumors]. Harefuah 141(12):1039-1041, 1090.  x;  x;  4;  4

46.  Yosepovich A^PI, Nass D^C, Zagatsky M^C, and Kopolovic J^PI. (2002) Chronic cholecystitis with bone metaplasia. A case report. Pathol Res Pract 198(11):765-766.  1.049;  45/66;  6;  6

47.  Kunin M^PI, Kopolovic J^PI, Avigdor A^C, and Holtzman EJ^PI. (2004) Collapsing glomerulopathy induced by long-term treatment with standard-dose pamidronate in a myeloma patient. Nephrol Dial Transplant 19(3):723-726.  2.976;  7/20;  10/51;  8;  8

48.  Yosepovich A^PI, Perelman M^C, Ayalon S^C, Papa M^PI, and Kopolovic J^PI. (2005) Syringomatous adenoma of the nipple: a case report. Pathol Res Pract 201(5):405-407.  1.049;  45/66;  0

Letters

Reviews, Commentaries, Hypotheses, Editorials

1.                  Davidson B, and Kopolovic J. (1995) [Molecular biology of human papilloma virus infection of the female genital tract]. Harefuah 129(10):417-420.

2.                  Kopolovic J, and Wolman M. (1996) Reasons underlying discrepancies in results between immunohistochemistry and molecular biology. Eur J Histochem 40(3):177-180.

3.                  Afek A, Shibi R, and Kopolovic J. (1997) Benign and premalignant breast lesions—clinico-pathological correlation. Harefuah 133(9):375-378 [Hebrew].

4.                  Yosepovich A, and Kopolovic J. (2002) [Advances in pathogenesis and molecular biology of endometrial carcinoma]. Harefuah 141(3):255-259, 314.

5.                  Davidson B, Goldberg I, Gotlieb WH, Kopolovic J, Risberg B, Ben-Baruch G, and Reich R. (2003) Coordinated expression of integrin subunits, matrix metalloproteinases (MMP), angiogenic genes and Ets transcription factors in advanced-stage ovarian carcinoma: a possible activation pathway? Cancer Metastasis Rev 22(1):103-115.

Other Publications

Representative Examples of Recent Participation in Scientific Conferences

Presentations

1.                  Davidson B, Trope CG, Risberg B, Goldberg I, Tell L, Kopolovic J, and Reich R. (May 2002) B1 integrin mRNA expression is downregulated in effusions and solid metastases in serous ovarian carcinoma. ASCO Annual Meeting, Orlando FL, US.

2.                  Odegaard EI, Cathrinel A, Abeler V, Kopolovic J, Onsrud M, Lazarovici P, Reich R, and Davidson B. (May 2002) Different roles for the nerve growth factor receptors TrkA and p75 in ovarian neoplasia. ASCO Annual Meeting, Orlando FL, US.

3.                  Shoenfeld Y, Rauova L, Gilbure B, Ziporen L, Kvapil F, Goldberg I, and Kopolovic J. (September 2002) Efficacy of affinity purified anti-dsDNA anti-idiotypic antibodies in the treatment of experimental SLE. 10^th International Congress on Antibodies and Antiphopholipids, Sicily, Italy.

4.                  Fridman E, Goldberg I, Yosepovich A, and Kopolovic J. (November 2003) TMA methodology and differential diagnosis of renal epithelial tumors. Annual Meeting of the Israeli Association of Pathologists, Eilat, Israel.

5.                  Blau A, Kunin M, Fenigstein H, Ben David A, and Kopolovic J. (May 2004) Pathological and epidemiological characteristics of adult patients with renal disease in central Israel: a 10 year retrospective review. 41^st Congress of the European Renal Association, Lisbon, Portugal.

6.                  Barshack I, Polak-Charcon S, Behar V, Vainshtein A, Zik O, Ofek E, Hadani M, Kopolovic J, and Nass D. (May 2004) Wet SEM: a novel method for rapid diagnosis of brain tumors. Israeli Society for Microscopy, Jerusalem, Israel.

7.                  Fridman E, Kopolovic J, Mor Y, Laufer M, and Ramon J. (November 2004) Systematic, standardized pathological examination of the prostate in radical cystoprostatectomy specimens raises the detection rate of prostatic carcinoma. 24^th Annual Meeting of the Israeli Urological Society, Eilat, Israel.

8.                  Fridman E, Pinthus JH, Kopolovic J, More O, Ramon J, and Mor Y. (November 2004) Expression of Cox-s in Wilms tumor: mmunohistochemical study using TMA methodology. 24^th Annual Meeting of the Israeli Urological Society, Eilat, Israel.

9.                  Fridman E, Pinthus JH, Kopolovic J, More O, Ramon J, and Mor Y. (June 2005) Expression of CYCLOOXYGENASE-2 (Cox-2) in Wilms tumor: Immunohistochemical study using TMA methodology. ESPU/AAP 2^nd Joint Meeting, Uppsala, Sweden.

10.              Fridman E, Pinthus JH, Laufer M, Mor Y, Ramon J, and Kopolovic J. (November 2005) The significance of negative AMACR staining in prostate cancer: sorting neuroendocrine prostatic cancer in challenging diagnostic cases. 25^th Annual Meeting of the Israeli Urological Society, Eilat, Israel.

11.              Polack-Sharcon S, Marduk C, Schwartz I, Fridman E, Reder I, Laufer M, Ramon J, and Kopolovic J. (November 2005) The value of fluorescence in situ hybridization (FISH) in the early diagnosis and followup of the transitional cell carcinoma. 25^th Annual Meeting of the Israeli Urological Society, Eilat, Israel.

12.              Fridman E, Kopolovic J, Mor Y, Laufer M, and Ramon J. (April 2006) Systematic standardized pathological examination of the prostate in radical cystoprostatectomy specimens raises the detection rate of prostatic carcinoma. 21^st Annual European Urology Association, Paris, France.

13.              Fridman E, Pinthus J, Laufer M, More Y, Ramon J, and Kopolovic J. (April 2006) The significance of negative AMACR staining in prostate cancer: sorting neuroendocrine prostatic cancer in challenging diagnostic cases. 21^st Annual European Urology Association, Paris, France.

14.              Davidson B, Goldberg I, and Kopolovic J. (October 2006) Differences in vascular antigenicity between normal and neoplastic tissues. 21^st Congress of the International Academy of Pathology, Budapest, Hungary.

Abstracts & Posters

1.                  Davidson B, Gotlieb WH, Ben Baruch G, Kopolovic J, Goldberg I, Nesland JM, Berner A, Bjamer A, and Byrne M. (September 1999) Expression of carbohydrate antigens in advanced-stage ovarian carcinomas and their metastases – a clinicopathological study. 17^th European Congress of Pathology, Barcelona, Spain.

2.                  Goldberg I, Davidson B, Reich R, Gotlieb WH, Ben Baruch G, Byrne M, Berner A, Nesland JM, and Kopolovic J. (September 2001) αV integrin is a novel marker of poor prognosis in advanced-stage ovarian carcinoma. 18^th European Congress of Pathology, Berlin, Germany.

3.                  Davidson B, Goldberg I, Gotlieb WH, Kopolovic J, Ben Baruch G, and Reich R. (September 2002) PEA3 is the second Ets family transcription factor involved in tumor progression in ovarian carcinoma. 9^th International Congress of the Metastasis Research Society, Chicago IL, US.

Invited Presentations

1.                  Fridman E, Skarda J, Kopolovic J, and Skardova I. (2005) Aplikacia tissue microarray (TMA) method for the detection of apoptosis in comparative pathology and diagnostics. Seminar at the University of Veterinary Medicine, Kosice, Slovakia.

2.                  Kopolovic, J. (2006) Amplification of Her2/Neu in breast carcinoma. 33^rd Congress of the Czeck Society of Pathologists ― 2^nd Satellite Symposium & Workshop on Molecular Biology, Olomouc, Czechoslovakia.

List of journals in which the author has published