Updated Feb 17, 2008
Department of Neurology
Hadassah Medical Organization
Kiryat Hadassah, Jerusalem 91120 ,Israel
Tel:+972-2-6776939
Telefax:+972-2-6426741
e-mail: karus@cc.huji.ac.il
Personal Details
Date of birth: 07.08.1962
Place of birth: Thessaloniki, Greece
Citizenship: Greek
MD license: 32037
Higher Education
9/1986: Graduation (MD degree) from "Aristotelion" University, Medical School, Thessaloniki, Greece.
1/1989-12/1993: PhD thesis, in Neuroimmunology / Neurobiology, entitled: "New therapeutic approaches for induction of tolerance in neurological autoimmune diseases", in the Laboratory of Neuroimmunology, Hadassah University Hospital, Jerusalem, and in the Department of Cell Biology, Weizmann Institute of Science, Rehovot, Israel, under the supervision of Profs O. Abramsky, S. Slavin, A. Ben-Nun.
1989-1994:
Specialization in clinical Neurology at the department of Neurology, Hadassah, Jerusalem, Israel.
8/1994: Boards in Neurology, in Greece and European UnionEEC.
10/1994: Board certification in Clinical Neurology (Israel)
4/1995: Boards Certification in Neurology in Israel.
Appointments at the Hebrew University
1/4/1997: Lecturer/Researcher C
1/4/1999: Senior Lecturer
6/2003: Associate Professor
Service in other Academic and Research Institutions
1999, 2001, 2003: Teaching (3 hours) in the post-graduation courses on Neurology in Tel Aviv University
2004 – 2007: Teaching courses at the Aristotelian University of Thessaloniki and the General Hospital in Athens
2001 – 2007: Teaching courses at the ESNI (European School of Neurology-Immunology) and the ENS, EFNI and ECTRIMS
2004 - today - Senior Fellowship and consultant in B' Neurological department, AHEPA Hospital, Aristotelian University, Thessaloniki, and General Hospital "Genimatas" Athens, Greece
Other Activities
Prizes:
8/1990: The "Lilian Nidermann-Shapira" prize for cerebro-vascular diseases (for the work on thalamic CVAs).
3/1992: The "Keren Hayesod for Israel" prize for the experimental work on EAE.
11/1994: The Young Investigator prize in the "European Committee for treatment and research in multiple sclerosis" congress (ECTRIMS).
Professional activities
1995-today: Head of the EAE Laboratory in the department of Neurology, Hadassah, Jerusalem.
1998-today: Head of the multi-disciplinary Multiple Sclerosis Clinic and Center in Jerusalem (Hadassah).
2006-today Head of the multi-disciplinary Multiple Sclerosis Center in Jerusalem (Hadassah).
1998-today: Member of the European "Steering Committee" for Bone Marrow Transplantation in multiple sclerosis.
1999-today: Board member of the European Council and Committee for Treatment and Research In Multiple Sclerosis
1999-today: Member of the Executiveexecutive board and the scientific committee of the European School of Neuroimmunology (ESNI)
2000-today: Member of the Executive board of Israel Society of Neuroimmunology
2000-today: Ad hoc reviewer in several international journals (have reviewed more than 60 papers) including Journal of Neurological Sciences, Multiple sclerosis, Neurology, Annals of Neurology, Journal of Neurology, European journal of Neurology,Journal of Neuroimmunology
1/2001-today: Member of the Advisory MS Board for TEVA-CORAL
4/2002: Organized the second annual meeting of the Israel Society of
Neuroimmunology
2003: Member of the International Advisory MS Board
2003: Member of the MS International and Asian Forum (supported by Schering Co)
2004: Member of the Executive Committee Scientific Committee of the INTERNATIONAL MS FORUM (8 members)
2004: Member of the Management Committee and SECRETARY GENERAL of the Mediterranean Neurological Society
2004:
Member of the Scientific Committee and International Advisory Board of MS SYMPOSIA International Forum
1/2006: Member of the European Charcot Foundation Steering Committee for stem cell transplantation in MS (12 members)
2006-today: Member of the Executive Board of the European Council and Committee for Treatment and Research In Multiple Sclerosis (5 members)
5/2007: Member of the Editorial Board of the journal: “Multiple Sclerosis”
10/2007: Member of the Medical Advisory Board of MEDInsight Research Institute
2000 – 2007: Preparation of teaching material for MDs and Neurologists, in more than 10 teaching courses in International congresses, and slide kit: "Neuroprotection in MS" distributed internationally
2006-today: Member of the Excellency centers committee in Hadassah and Deputy Head of the committee for Autoimmunity
Participation in clinical trials
1993-1995: Principal Investigator of the Linomide-double blind clinical trial multiple sclerosis.
1995-1997:
Investigator of the Rebif multi-center clinical trial in Multiple sclerosis
1998: Principal Investigator in the AVONEX multi-national clinical trial in progressive Multiple Sclerosis.
1999: Principal Investigator in the oral COPAXONE multi-national clinical trial in relapsing multiple sclerosis
2001: Principal Investigator in the ANTEGREN multi-national clinical trial in relapsing multiple sclerosis
2001: Principal Investigator in the BETAFERON multi-national clinical trial in early monosymptomatic multiple sclerosis
2003: Principal Investigator in the BEST (Schering) clinical trial in relapsing multiple sclerosis
2003: Principal investigator in the BEYOND international study
2004: Principal Investigator in the Copaxone combination
2004: Chief Scientific Officer and Principal Investigator in the "HIPPOCRATES" multi-center study
2004: Chief Scientific Officer and Principal Investigator in the "Copaxone antibodies" multi-center study
2005: Principal Investigator in the Laquinimod international trial in MS
2005: Principal Investigator in the BENEFIT international trial in MS
2007: Principal Investigator in the TYSABRI international trial in MS
2007: Principal Investigator in the REFLEX inernational trial in MS
2007: Principal Investigator and chief scientist in the AVONEX-REGULATORY CELLS trial in MS
2007: Principal Investigator in the Mesenchymal stem cells trial in MS and ALS
2007: Principal Investigator and coordinator of all Israeli sites on the International Laquinimod Phase III trial and responsible for the immunological studies
Research Grants
1994-1995: The Chief Scientist of Ministry of Health grant for the research in the development of experimental treatments for multiple sclerosis. (50,000 NIS) [# 12, 13]
1998: The Harry Stern Center for research in Alzheimer's disease, grant.
($ 100,000/3)
2002: The National Institute of Neuropsychobiology Grant ($ 100,000/4) [#31,34,37,39]a
1995-today: Various Grands from TEVA company, PHARMACIA, BIOGEN and SCHERING for research of immunomodulating treatments in MS. (summing to $ 500,000 ) [# 29, 28, 26, 24, 22, 19,18, 17, 16, 11, 8, 3, 4]
2007: Grant from Teva Pharmaceuticals for serving as one of the main immunological laboratories for the two phase III international Laquinimod studies ($ 180,000x2= $ 360,000)
For Publications see PubMed |