Department of Prosthodontics
The Hebrew University-Hadassah
School of Dental Medicine
P.O.Box 1172, Jerusalem
Telephone (02) 677-6142
Fax 972-2-642-9683
E-mail: mhouri@cc.huji.ac.il
Born 1.6.1969 in Tunisia
Education
1989-1991 B. Med. Sc. - Hebrew University – Hadassah School of Dental Medicine.
1992-1994 D.M.D - Hebrew University – Hadassah School of Dental Medicine.
1994 D.M.D. degree awarded
Thesis: Human monocyte response to cementum extracts from periodontally diseased teeth: Effect of conditioning with tetracycline. Supervisors: A. Soskolne, A.Stabholz, L. Shapira #1
1996-2002 Ph.D. study in Oral Biology, Hebrew University – Hadassah School of Dental Medicine. “Molecular mechanisms in the pathogenesis of periodontal disease”. Supervisors: A. Soskolne, L. Shapira
1996-2002 Graduate Diploma in Prosthodontics (with distinction), Hadassah Medical Centers.
Academic Positions
2002 Lecturer in prosthodontics in the department of prosthodontics
2009 Senior lecturer
Academic and Profession Experience
2002-2004 Member of the Teaching Committee, The Hebrew University-Hadassah School of Dental Medicine
2002-2006 Member of the testers committee in dentistry-ministry of health
2004 - Member of the Admissions Committee, The Hebrew University-Hadassah School of Dental Medicine
2005 - Member of the Committee for Supervision of DMD Theses, The Hebrew University-Hadassah School of Dental Medicine
2006 - Member of "The Bio-Medical Sciences in Dental Medicine" Committee, The Hebrew University-Hadassah School of Dental Medicine
2006 - Member of the professional committee of Prosthodontics-Israel Dental Association
2006 - Member of the examination committee of Prosthodontics-Israel Dental Association
2008 - Member of the Teaching Committee, The Hebrew University-Hadassah School of Dental Medicine
Awards and fellowships
1991 - Distinction award for B. Med. Sc. degree.
1995 - Hermel award for D.M.D. thesis (HUHSDM).
1995 - Foulkes foundation fellowship - London.
1995 - Hatton competition - IADR Israel division - 2nd place.
1995 - Prof. Michaeli award for Ph.D. thesis
2000 - Recipient of the award of excellence in Ph.D. studies, Hadassah Medical Center
2001 - IADR/Lion Dental Research Award in Microbiology and Immunology
2003 - Frank Popper award for Post-doc study in the Department of Prosthodontics
Membership in Professional Societies
1996 - Israel Dental Association
1996 - International Association for Dental Research
1999 - Israel Society of Oral Rehabilitation
Reviewer in academic journals
2006 - Oral Diseases
2008 - Ad hoc reviewew in JDR
2008 - Archives of Oral Biology
2008 - Odontology
Research Interests
§ Basic research in the area of pathogenesis of periodontal disease and genetic susceptibility
§ The effect of light and laser energy on the inflammatory response
§ Biocompatibility of dental materials
Research Projects
§ The local inflammatory response to Porphyromonas gingivalis in IFNy or IL-4 deficient mice.
§ Mixed infection of Porphyromonas gingivalis and Fusobacterium nucleatum in a murin model. Bacterial interaction and possible regulation by immunization.
§ Human neutrophil Toll-like receptor 2 activation: a mechanism for Porphyromonas gingivalis survival?
§ Microarray analysis of the human neutrophil response to Porphyromonas gingivalis.
§ Exposure to visible light modulates immune cell cytokine production: characterization of the effect and the mechanism
§ Phototoxic Effect of Non-Coherent Visible Light on Multi-Species Biofilm
Recent Publications
1. Polak D, Wilensky A, Shapira L, Weiss EI, Houri-Haddad Y (2009). Immunization of mice with P. gingivalis or F. nucleatum modulates the inflammatory response, but fails to prevent experimental periodontitis. J Clin Periodontol. Accepted for publication.
2. Polak D, Wilensky A, Shapira L, Halabi A, Goldstein D, Weiss EI, Houri-Haddad Y (2009). Mouse Model of Experimental Periodontitis Induced by P. gingivalis/F. nucleatum Infection: Bone Loss and Host Response. J Clin Periodontol. Accepted for publication.
3. Beyth N, Houri-Haddad Y, Baraness-Hadar L, Yudovin-Farber I, Domb AJ, Weiss EI (2008) Surface antimicrobial activity and biocompatibility of incorporated polyethylenimine nanoparticles. Biomaterials. Nov;29(31):4157-63
4. Houri-Haddad Y, Halabi A , Soskolne WA (2008) Inflammatory response to chlorhexidine, minocycline HCl and doxycycline HCl in an in vivo mouse model.. Journal of Clinical Periodontology. Sep;35(9):783-8
5. Hochman N, Houri-Haddad Y, Koblinski J, Wahl L, Roniger M, Weiss E.I, Hochman J (2008) Cranberry juice constituents impair lymphoma growth and augment the generation of anti-lymphoma antibodies in syngeneic mice. Nutrition and Cancer: An International Journal. 60(4):511-7
6. Houri-Haddad Y, Wilensky A., Shapira L (2007) T cell phenotype as risk factor for periodontal diseases. Periodontology 2000. 45:67-75.
7. Houri-Haddad Y, Soskolne WA, Halabi A, Shapira L (2007) IL-10 gene transfer attenuates P. gingivalis induced inflammation. Journal of Dental Research. 86(6);560-564.
8. Mizrahi B, Shapira L, Domb AJ and Houri-Haddad Y (2006) Citrus oil and magnesium salt as antibacterial and anti-inflammatory agents. J Periodontology. 77(6):963-8.
9. Houri-Haddad Y, Soskolne WA, Halabi A, Shapira L (2005) The effect of immunization on the response to P. gingivalis infection in mice is adjuvant-dependent. Journal of Clinical Periodontology. 32:933-7.
10. Wilensky A, Gabet Y, Houri-Haddad Y, Yumoto H, Genco CA, Shapira L (2005) Three dimensional quantification of alveolar bone loss in Porphyromonas gingivalis-infected mice. J. Periodontology. 76(8):1282-6.
11. Weiss EI, Houri-Haddad Y, Greenbaum E , Hochman N, Ofek I, Zakay-Rones Z (2005) Cranberry Juice Constituents Affect Influenza Virus Adhesion and Infectivity. Antiviral Research. 66(1):9-12.
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