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Menachem Hanani, Ph.D.

 

Laboratory of Experimental Surgery

Department of Surgery

Hadassah University Hospital, Mount Scopus

Jerusalem 91240, Israel

and Department of Physiology

Hebrew University-Hadassah Medical School

Jerusalem, 91120, Israel.

Work telephone: 972-2-5844721

Fax: 972-2-5823515

e-mail address: hananim@cc.huji.ac.il

 

 

Personal details

 

Born: July 29, 1945, Israel.

Citizenship: Israeli

Martial status: Married, two children

 

Higher Education

 

1968 - B.Sc. in Chemistry (secondary field: physics), The Hebrew University

 

1970 - M.Sc. in Physical Chemistry. The research work was done at the Physics Department, the Hebrew University, Supervisor, Prof. M. Schieber,

 

1973 - Visiting Student at the Max Planck Institute for Biological Cybernetics, Tübingen, and at the Institute for Neurobiology KFA, Jülich, Germany, Sponsor, Prof. H. Stieve

 

1976 - Ph.D. in Physiology (Neurobiology), The Hebrew University, Supervisor, Prof. P. Hillman

 

1976-8 Postdoctoral Fellow  Lab. of Neurophysiology, NINDS, NIH, Bethesda, MD, USA, Sponsor, Dr. A. Lasansky

 

Academic appointments at the Hebrew University

 

1974 - 1976  Teaching Assistant and Instructor 

 

1.10.1979 - 1985  Lecturer in Physiology

 

1986 - 1994  Senior Lecturer in Physiology 

 

1994 - Associate Professor 

 

Other Appointments at the Hebrew University

 

1968 – 1971  Research Assistant, Physics Department 

 

Service at Other Institutions (Note: brief visits in institutions or laboratories are not listed;  only visits of three weeks or longer, in which actual research was performed are listed.)

 

1976 - 1978  Visiting Fellow, Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, NIH, USA

 

Aug. - Sept. 1978  Research Associate at the Marine Biological Laboratory,

 Woods Hole,  MA, USA

 

Sept. 1979-Jan. 1980  Honorary Research Fellow, University College, London, UK

 

Sept. - Oct. 1981  Research Associate, Ruhr University, Bochum, West Germany

 

Aug. - Nov. 1982  Research Fellow, University College London, UK

 

July - Aug. 1984  Special Project Associate, Mayo Clinic, Rochester, Minnesota, USA

 

July- Sept. 1986  Special Project Associate, Mayo Clinic, Rochester, MN, USA

 

September 1987  Visiting  Scientist,  Dept. of Anatomy, University College, London, UK

 

June 1988 - Visiting Scientist, Department of Physiology, Ruhr University, Bochum, Germany

 

July 1989-Sept. 1990  Visiting Scholar, Ohio State University, Columbus, OH, USA

 

October 1991 - Visiting Scientist, Mayo Clinic, Rochester, MN, USA

 

September 1992 - Visiting Scientist, Cellular Neurobiology Lab., M. Delbrück  Center for Molecular Medicine Berlin, Germany

 

Nov. - Dec. 1992  Special Project Associate, Mayo Clinic, Rochester, MN, USA

 

July - August 1993  Research Associate, Mayo Clinic, Rochester, MN, USA

 

Jan. - Feb. 1996  Visiting Scientist, Institute for Brain Research, Leipzig University, Germany

 

July - Oct. 1996  Visiting Scientist, Mayo Clinic, Rochester, MN, USA

 

Oct. 1997 - Visiting Scientist, Institute for Brain Research, Leipzig University, Germany 

 

July-Aug. 1998  - Visiting Scientist, Institute for Brain Research, Leipzig University, Germany

 

Aug. - Oct. 1998  Visiting Scientist, Mayo Clinic, Rochester, MN, USA

 

Sept. - Oct. 1999  Visiting Scientist, Mayo Clinic, Rochester, MN, USA

 

July-Sept. 2000  Academic Visitor, Oxford University, UK

 

July-Oct. 2002 - Visiting Scientist, Institute for Brain Research, Leipzig University, Germany

 

July-Aug. 2003 - Visiting Professor, Albert Einstein College of Medicine, New York, USA.

 

Aug.–Nov. 2004 - Visiting Professor, Albert Einstein College of Medicine, New York, USA.

 

Other Activities

 

Administrative Duties

 

1979 – present,  Director of the Laboratory of Experimental Surgery Hadassah University Hospital, Mount Scopus.

 I am responsible for all the aspects of running a research lab: obtaining financial support, design of research projects, negotiating with various levels of hospital management and administration, purchase of equipment, training and supervising technicians and students.

 

1982 - present.   Member of the Research Committee of the Hadassah University Hospital, Mount Scopus.

 

1990-present  Director of the animal facility of the Hadassah University Hospital, Mount Scopus.

 Duties include: supervision of two technicians, budget management, ordering equipment and supplies, contacts with Ministry of Health and other authorities.

 

1994 - present   Member of the Hebrew University-Hadassah Medical School Committee on the Ethical Use of Animals.

 

1995 - 1998  Chairperson, Neurobiology Teaching Division, the Hebrew University. My duties included: interviewing candidates for the Graduate Program of Neurobiology of the Hebrew University, advising students and approving their courses, organizing new graduate course, assigning examiners for theses and final exams of Master’s degree students, assigning referees for Ph.D. lectures.  In 1997-8 I organized the neurobiology seminar of the Hebrew University – the ‘Nervous Club’.      

 

2000 -  Chairperson, Research Committee of the Hadassah University Hospital, Mount Scopus.

 

Consultant Assignments

 

1994-9, Peptor Co., Rehovoth, Israel

 

1996-7, Neuromod Co., Boston, MA, USA

 

2000-5, NIH grant to Drs. Adam Rich and Gianrico Farrugia, Mayo Clinic, Rochester, MN, USA.

 

Guest Editor

 

Microscopy Research and Technique, Vol. 47, 1999, issues number 4 and 5 dedicated to the topic: “Interstitial Cells of Cajal”.

 

Reviewer of Journals and Serials

 

         American Journal of Physiology

         Autonomic Neuroscience

         BMC Infectious Diseases

         Brain Research.  Developmental Brain Research

         Cell and Tissue Research

         Gastroenterology

         European Journal of Neuroscience

         Glia

         Handbook of Physiology (American Physiological Society)

         Histology and Histopathology

         Journal of Autonomic Pharmacology

         Journal of Basic and Clinical Physiology and Pharmacology

         Journal of Comparative Physiology

         Journal of Neurophysiology

         Journal of Neurochemistry

         Journal of Veterinary Medicine

         Journal of Physiology

         Life Sciences

         Neuroscience

         Neurogastroenterology and Motility

         Neuroscience Letters

         Pain

         Pharmacological Research

         Veterinary Research Communications

 

Reviewer of Grant Proposals

 

         US-Israel Binational Science Foundation (BSF)

         Joint Research Fund of the Hebrew University and Hadassah

         Israel Academy for Sciences and Humanities

         Chief Scientist's Office, Israeli Ministry of Health

         The Hebrew University Fund for Applied Research

         The National Institute for Psychobiology in Israel

         German-Israel Foundation for Scientific Collaboration (GIF)

         National University of Singapore

         The Welcome Trust

 

 Awards

 

ý      Israel Labor Federation, Studentship, 1969-1970.

 

ý      Poznansky Studentship, the Hebrew University, 1973-1974.

 

ý      Max Planck Institute for Biological Cybernetics, Tübingen, Germany, Studentship, 1973.

 

ý      National Institutes of Health, USA, Fogarty Fellowship, 1976-1978.

 

ý      EMBO Fellowship, 1979 (not used)

 

ý      Wellcome Foundation Fellowships at University College London, 1979, 1982.

 

ý      Neufeld Prize from the BSF for the best research proposal in Biomedicine, 1999.

 

Recent and Current Research Grants

 

1992-1995  US-Israel Binational Science Foundation (BSF), grant #91-00135, "Studies on the Enteric “Nervous System", Co-Principal Investigator (with Prof. J.H. Szurszewski), (US$ 110,000/110,000).

 

1993-1999   Peptor Company, "Characterization of Peptide Receptors with Smooth Muscle Preparations", Principal Investigator, (US$ 40,000).

 

1994-1997  Israel Science Foundation, administered  by Israel Academy for Sciences and Humanities, "An Investigation of Glial Cells", Principal Investigator, (US$ 85,000).

 

1996-1999  US-Israel Binational Science Foundation (BSF), grant #95-00568, "Studies on the Enteric “Nervous System", Co-Principal Investigator (with Prof. J.H. Szurszewski),  (US$ 110,000/110,000).

 

1997-1998   Chief Scientist's Office, Israeli Ministry of Health, “A Study of Intussusception in Mice”,  Principal Investigator, (US$12,000).

 

1999-2000   Hadasit and Horowitz Foundation, “Pharmacologically Active Agents in Bran”, Principal Investigator, (US$37,000).

 

1999-2002  US-Israel Binational Science Foundation (BSF), grant #98-00185, "An Investigation of Enteric Neurons and Interstitial Cells of Cajal", Co-Principal Investigator (with Prof. J.H. Szurszewski),  (US$ 105,000/105,000).  This application won the Neufeld prize for research in the health sciences, (additional US$10,000).

 

2003-2007  Israel Science Foundation, administered  by Israel Academy for Sciences and Humanities, "Basic Mechanisms of Visceral Pain", Principal Investigator,  US$180,000.

 

2004-2008  US-Israel Binational Science Foundation (BSF), grant #2003262 “Gap-Junctions – their Role in Pain Mechanisms”.  Co-Principal Investigator (with Prof. D.C. Spray), US$132,000. 

 

Society Memberships

 

§         Israel Society for Physiology and Pharmacology (1980)

 

§         Israel Society for Neuroscience   (1992)

 

§         European Neuroscience Association (1980)

 

§         International Brain Research Organization (1982)

 

§         International Brain-Gut Society (1992)

 

§         Society for Neuro gastroenterology (1991)

 

§         International Society for Developmental Neuroscience (1991)

 

§         American Physiological Society (1997)

 

§         Center for Pain Research, the Hebrew University (1999)

 

Teaching Experience

 

§         1974-1976, Instructor in student laboratories in the courses:

§         "Sensory Physiology" for biology students.

§         "General Physiology" for biology students.

§         "Vertebrate Anatomy" for medical students, nursing students and agronomy students.

§         1979-1984, Instructor in student laboratories in the course "Systems Physiology" for medical students.

 

 

Teaching Duties at the Hebrew University since 1998

 

M.Sc. Students

 

Pavel Cherkas, 2001, Cum laude, #79,80 

 

Tali Kobilo, 2002, Cum laude,  #75,84

 

Uri Shpolanski, (with Prof. D. Lichtstein), 2001, Summa cum laude

 

Nir Duvdevani (with Prof. R. Rahamimoff), 2003, Summa Cum laude

 

Vitali Belzer #69,75,76,86

 

Pavel Dublin

 

Raya Kushnir

 

Ilan Schuldiner

 

Ph.D. Students

 

Tian Ying Huang, degree awarded  2006  #79,80,82,89,92,94,95,96

 

Pavel Cherkas, (with Prof. Michael Tal) #83,89,92

 

Post-doctoral Fellow:

 

Dr. Lin Zhong 1994-5  #54,64

 

MD Students Who Did Their Thesis Under my Supervision:

 

Annina Roitenberg, 2001

 

Amir Bar-Shai, 2002  #88

 

Residents Who Did the “Basic Science” Training Under my Supervision:

 

Dr, Mahmood Badriyah, 2000

 

Dr. Tzeela Cohen, 2001

 

Dr. Isabella Schwartz, 2002

 

Lecturer in the courses:

 

§         "Systems Physiology" for second year pharmacy students (GI physiology), 1985-2005 (a required course).

 

§         "Medical Physiology" for second year medical students (GI physiology), 1984-1985, 1991, 1994-2005, (a required course). 

 

§         "Physiology" for second year nursing students (GI physiology) 1985,1986, 1995, 2000-2005 (a required course).

 

§         "Topics in the Physiology of the Digestive System and Kidney", for graduate students

 

§         (course  coordinator), 1984-2005 (an elective course). "Advanced Physiology" for second year biology students, 1992 - 2001, (an elective course).

 

§         "Principles of Neurobiology", for graduate students, 1993- 2005, course coordinator 1995-1998 (a required course).

 

List of Publications

 

M.Sc. thesis:  The effects of electric field and pressure on crystal growth. Supervisor: Prof. M. Schieber, 1970.

 

Ph.D. thesis:  Electrophysiological  examination  of the light and dark adaptation process in invertebrate photoreceptors. Supervisor: Prof. P. Hillman 1976.

 

Articles 

 

1. Hanani, M.  and  Schieber, M. Crystallization of Rochelle salt in electric fields. J. Appl. Physics 42: 206-210, 1971.

 

2. Hillman, P. and Hanani, M. Visual information processing - the many splendored photoreceptor. Advances in Behavioral Biology, 15: 11-19, 1975.

 

3. Hanani, M.  and Hillman, P.  Adaptation and facilitation in the  barnacle  photoreceptor.  J. Gen. Physiol. 67: 235-249, 1976.

 

4. Stieve,  H. and Hanani, M. Light and dark adaptation of crayfish visual cells depending on extracellular calcium concentration.  Z. Naturforsch. 310: 324-327, 1976.

 

5. Hanani, M. and Shaw, C. A potassium contribution to the response of the barnacle photore­ceptor. J. Physiol. (Lond.) 270: 151-163, 1977.

 

6. Hanani, M. Visual adaptation at the receptor level. Doc. Ophthalmol. Suppl. Ser. 11: 197-201, 1978.

 

7. Fein, A. and  Hanani, M. Light induced increase in discrete waves in the dark in Limulus ventral photoreceptors.  Brain Research 156: 157-161, 1978.  

 

8. Shaw,  C.,  Hanani, M. and Hillman, P. Effects of Mn and Ca ions  on  the prolonged depolarizing afterpotentials  in barnacle photoreceptors.  Biophys. Struct. Mechanism 5: 223-230, 1979.

 

9. Hanani, M. and Hillman, P. Absorption of light by metarhodopsin modifies the effect  of  a conditioning light on the barnacle photoreceptor.  Biophys. Struct. Mechanism, 5: 231-235, 1979.

 

10. Normann,  R.A., Kolb, H., Hanani, M., Pasino, E. and Holub, R. Orientation of horizontal axon terminals in the streak of turtle retina. Nature  280: 60-62, 1979.

 

11. Hanani, M. and  Vallerga,  S. Rod and cone signals in the horizontal cells of the tiger salamander retina. J. Physiol. (Lond.) 298:  397-405, 1980.

 

12. Hanani, M.  and  Fein, A. Diamide, a sulfhydryl oxidizing agent, modifies the light response of Limulus  ventral photoreceptors. Neuroscience Letters 21: 165-170, 1981. 

 

13. Hanani, M., Baluk, P. and Burnstock, G. Myenteric neurons express electrophysiological and morphological  diversity in tissue culture. J. Auton. Nervous System   5:  155-164, 1982.

 

14. Hanani, M. and Hillman, P. The contribution of pigment transitions to sensitivity changes in  the barnacle photoreceptors and the correlation with prolonged depolarizing  after-po­tential. Bioph. Struct. Mechanism  8: 161-172, 1982.

 

15.  Jessen,  K., Saffrey, M.J., Baluk, P., Hanani, M. and Burnstock, G. The enteric  nervous system  in tissue culture.  III. Studies on neuronal survival and retention  of  biochemical and morphological differentiation.  Brain Research  262: 44-62, 1983.

 

16. Hanani, M.   Receptive field properties of horizontal cells in the tiger  salamander  retina: contributions of rods and cones. Vision Research  23: 1115-1119, 1983.

 

17. Nissan,  S.,  Vinograd,  I., Hadary, A., Merguerian, P., Zamir, O., Lernau, O.Z. and Hanani, M.  Physiological and pharmacological studies on the internal anal sphincter.  J. Pediatr. Surg. 19: 12- 14, 1984.

 

18. Hanani, M.  and Burnstock, G. Substance P evokes slow and fast  responses  in  cultured myenteric neurons.  Neuroscience Letters  48: 19-23, 1984.

 

19. Hanani, M. Electrophysiological studies of myenteric neurons in tissues culture. In: Mechanisms of Intestinal Motility and Secretion. A. Bennett and G. Velo, eds., Plenum Press, New York, pp. 73-86, 1984.

 

20. Vinograd,  I.,  Hanani, M., Hadary, A., Merguerian, P., Goldberg, M.  and  Nissan,  S. Neuropharmacological   study  of  the  internal  anal  sphincter  in  an   animal   model.   Harefuah  57: 221-224, 1984. (in Hebrew)

 

21. Vinograd,  I., Hanani, M., Hadary, A., Merguerian, P. and Nissan, S. An animal  model  for the study of internal anal sphincter activity. Europ. Surg. Res.  17: 259-263, 1985.

 

22.  Hanani, M.  and  Burnstock, G. The actions of substance P and  serotonin  on  myenteric neurons in tissue culture. Brain Research 358: 276-281, 1985.

 

23. Hanani, M. and Burnstock, G. Synaptic activity of myenteric neurons in tissue culture.  J. Auton. Nervous System 14: 49-61, 1985.

 

24. Goldberg,  M.,  Hanani, M. and Nissan, S. The effects of serotonin on  the  internal  anal sphincter: in-vivo manometric study in rats. Gut  27: 49-54, 1986.

 

25. Hanani, M.  The  relation  between sensitivity changes and   response  time  scale  in  the barnacle photoreceptor. Vision Research 26: 819-825, 1986.

 

26. Hanani, M.  and Nissan, S. Phenazine methosulfate induces acetylcholine  release  in  the guinea-pig ileum. Life Sciences 39: 1508-1812, 1986.

 

27. Hanani, M., Lernau, O.Z., Zamir, O. and Nissan, S. Nerve mediated responses to  drugs and  electrical  stimulation in aganglionic muscle segments  in  Hirschsprung's  disease.  J. Pediatr. Surg.  21: 848-851, 1986

 

28. Vatashsky, E., Haskel, Y., Nissan, S. and Hanani, M. Effects of morphine on mechanical  activity of the common bile duct isolated from the  guinea-pig. Anesth.  Analg.  66:245-258, 1987.

 

29 Goldberg,  M.,  Vatashsky,  E.,  Haskel,  Y., Nissan, S. and  Hanani, M.  The  effect  of meperidine  on the guinea-pig extrahepatic biliary tract. Anesth.  Analg.  66:1282-1286, 1987.

 

30. Hanani, M.,  Selinger,  Z., Chorev, M. and Gilon, C. The actions  of  receptor-selective substance   P  analogs  on  myenteric  neurons:  an  electrophysiological   investigation.  Europ. J. Pharmacol. 153:247-253, 1988.

 

31. Hanani, M.,  Zamir, O. and Baluk, P. Glial cells in the guinea pig  myenteric  plexus  are dye coupled. Brain Research, 497:245-249, 1989.

 

32. Hanani, M., Lernau, O.Z., Zamir, O. and Nissan, S. Hirschsprung’s diseases: recent advances in the understanding of its pathophysiology. In: Nerves and the Gastrointestinal Tract. M.V. Singer and H. Goebell, eds., MTP Press, Lancaster, pp. 611-617, 1989.

 

33. Hanani, M. Rapid effects of MPTP in the mouse colon. Europ. J. Pharmacol. 175:273-277, 1990.

      

34. Ron, D.,  Hanani, M., Gilon, C., Selinger, Z. and Chorev, M. CCK receptor subtypes: Studies with CCK analogs. In: Peptides 1990, Proceedings of the 21th European Peptide Symposium 1990, E. Giralt and D. Andreu, eds., Leiden, ESCOM, pp. 702-703,  1990.

 

35. Zamir,  O.  and  Hanani, M. Dye-coupling in intestinal smooth muscle.  Are  gap  junction  required for intercellular coupling? Experientia  46:1002-1005, 1990.

 

36 Bauer, A.J., Hanani, M., Muir T.C. and Szurszewski, J.H. Intracellular recordings  from the gallbladder ganglia of the opossum. Am. J. Physiol. 260: G299-G306, 1991.

 

37. Hanani, M. The actions of oxidation-reduction agents on neurotransmitter release. In: Presynaptic Regulation of Neurotransmitter Release: a Handbook.‚ Feigenbaum, J.J. and Hanani, M. (eds.)‚ Freund Publishing Co., London and Tel Aviv, pp. 1321-1331, 1991.

 

38. Hanani, M. and Wood, J.D. Corticotropin releasing hormone excites  myenteric  neurons in the guinea-pig small intestine. Europ. J. Pharmacol. 211:23-27, 1992

 

39. Hanani, M. Visualization of enteric and gallbladder ganglia with  a vital  fluorescent  dye. J. Auton. Nervous System 38:77-84, 1992.

 

40. Maudlej, N. and Hanani, M. Modulation of dye coupling among glial cells in the myenter­ic and submucosal plexuses of the guinea pig.  Brain Research  578:94-98, 1992.

 

41. Vromen,  A. and Hanani, M. Pentazocine reduces cholinergic responses in  the  guinea-pig extrahepatic   biliary   tract  by  a  non  opiate  mechanism.   J.  Basic   Clin.   Physiol.  Pharmacol.  3:71-79, 1992.

 

42. Ron, D., Gilon, C., Hanani, M., Vromen, A., Selinger, Z. and Chorev, M. N-methylated analogs  of  Ac[Nle28,31]CCK(26-33) - synthesis, activity and receptor  selectivity. J. Med. Chem. 35:2806-2811, 1992.

 

43. Hanani, M., Udassin, R., Ariel, I. and Freund, H.R. A simple and rapid method for stain­ing  the  enteric  ganglia:  application  for  Hirschsprung's  disease. J.  Pediatr.  Surg. 28:939-941, 1993.

 

44. Christofi,  F.L.,  Hanani, M., Maudlej. N. and Wood, J.D. Enteric glial  cells  are  major  contributors  to formation of cAMP in myenteric plexus cultures from adult  guinea-pig small intestine. Neuroscience Letters 159:107-110, 1993. 

 

45. Hanani, M. Neurons and glial cells of the enteric nervous system: studies in tissue culture.  J. Basic Clin. Physiol.  Pharmacol. 4:157-179, 1993.

 

46. Hanani, M.  Are gap junctions necessary for cell-to-cell coupling in  smooth  muscle?  An  update. Can. J. Physiol. Pharmacol. 71:625-626, 1993.

 

47. Haskel, Y. and Hanani, M. Inhibition of gastrointestinal motility by MPTP via  adrenergic and dopaminergic mechanisms. Digest. Dis. Sci. 39:2364-2367, 1994.

 

48. Hanani, M., Xia, Y. and Wood J.D. Myenteric ganglia from the adult  guinea-pig  small intestine in tissue culture. Neurogastroenterol. Motility  6: 103-118, 1994.

 

49. Hanani, M. and Reichenbach, A. Morphology of HRP-injected glial cells in the myenteric plexus of the guinea-pig. Cell Tissue Res. 278:153-160, 1994.

 

50. Hanani, M., Ermilov, L., Louzon, V., Schmalz, P.F., Miller, S.M. and Szurszewski, J.H. Three  dimensional reconstruction of myenteric neurons of the guinea-pig.  SPIE  Proc.  359:730-735, 1994.

 

51. Hanani, M., Louzon, V., Udassin, R., Freund, H.R., Karmeli, F. and Rachmilewitz,  D. Nitric  oxide-containing nerves in bowel segments of patients with  Hirschsprung's  dis­ease. J.   Pediatr. Surg .30:818-822, 1995.

 

52. Hanani, M.  and  Maudlej,  N. Intracellular recordings  from  intramural  neurons  in  the  guinea-pig urinary bladder. J. Neurophysiol.  74:2358-2365, 1995.

 

53. Lernau,  O.Z.  and  Hanani, M. Hirschsprung's  disease,  clinical  and  neurophysiological aspects. In: Handbook of Autonomic Nervous System Dysfunction, A.D. Korczyn, ed., Marcel Dekker, pp. 117-128, 1995. 

 

54. Bitan, G., Beherens, S., Matha, B., Mashriki, Y., Hanani, M., Kessler, H. and Gilon,  C.  New backbone cyclic substance P analogs. Lett. Peptide Sci. 2:121-124, 1995.

 

55. Miller,  S.M., Hanani, M., Schmalz, P.F. Kuntz, S. and Szurszewski, J.H. A  light,  elec­tron,  and  confocal  microscopy study of the mouse  superior  mesenteric  ganglion.  J. Comp. Neurol 365:427-444, 1996.

 

56. Abu-Dalu,  R., Zhang, J.M. and Hanani, M. The actions of ketotifen on intestinal  smooth  muscles. Europ. J. Pharmacol., 309:189-193, 1996.

 

57. Bitan,  G., Zeltser, I., Byk, G., Halle, D., Mashriki, Y., Glushov, E.V., Sukhotinski,  I.,  Hanani, M.,  Selinger,  Z. and Gilon, C. Backbone cyclization of  C-terminal  part  of  substance  P.  Part  1: The important role of the sulphur in position 11.  J.  Peptide  Sci.  2:261-269, 1996.

 

58. Nissan,  A.  Mashriki,  Y., Zhang, M.J., Haskel, Y. and Freund, H.R.  and  Hanani, M. Direct  inhibitory  effect  of  erythromycin on  the  gallbladder  muscles.  J  Gastroint. Surgery  1:331-336, 1997.

 

59. Nissan  A,  Zhang, MJ, Lin Z, Haskel, Y, Freund, HR  and Hanani, M   The  contribution  of  inflammatory mediators and nitric oxide to lipopolysaccharide (LPS)-induced intussus­ception in mice. J. Surg. Res. 69:205-207, 1997.  

 

 60. Bitan,   Sukhotinski,  I.,  Mashriki, Y., Hanani, M.,  Selinger,  Z. and Gilon, C. Synthesis and biological activity of novel backbone-bicyclic substance  P analogs containing lactam and disulfide bridges.  J.  Peptide  Res.  49:421-426, 1997.

 

61. Hanani, M.,  Lin,  Z.,  Louzon, V, Brenner, T. and Boneh, A. Phorbol  esters  alter  the morphology of cultured myenteric glia via a PKC-independent mechanism.  Neuroscience Letters, 233:61-64, 1997.

 

62. Parr, E.J., Myles, E.B., Hanani, M., Seror D., Riabowol, K.T. and Sharkey, KA. Immunoreactivi­ty for the FAS ligand in the mammalian enteric nervous system.  Cell   Tissue  Res. 290:21-29, 1997.

 

63. Nissan, A., Zhang, J.M., Haskel, Y., Freund, H.R. and Hanani, M. Erythromycin directly inhibits contraction of rat urinary bladder smooth muscle. Surgical Forum,  50:780-782, 1997.

 

64. Hanani, M.  Microscopic analysis of pressure ejection drugs from micropipettes. J. Basic Clin. Physiol. Pharmacol, 8:57-71, 1997.

 

65. Hanani, M.  and Lasser-Ross, M. Activity dependent changes in intracellular calcium in myenteric neurons. Am. J. Physiol.  273:G1359-G1363, 1997.

 

66. Granovsky-Grisaru,  S.,  Dan, I., Grisaru, D., Lavie, O., Aboulafia,  I.,  Diamant,  Y.Z. and Hanani, M.  Effects of erythromycin on contractility of isolated myometrium  from pregnant rats. Am. J. Obstet. Gynecol. 178:171-174, 1998.

 

67. Hanani, M. Louzon, V., Miller, S.M. and Faussone-Pellegrini SM.  Visualization of interstitial cells of Cajal in the mouse colon with vital staining. Cell   Tissue Res. 292:275-282, 1998.

 

68. Hanani, M., Ermilov, L.G., Schmalz, P.F., Louzon, V., Miller  S.M. and Szurszewski,  J.H.     The three  dimensional  structure  of myenteric neurons. J. Auton. Nervous System. 71:1-9, 1998.

 

69. Lin Z., Cohen P.,  Nissan  A.,   Haskel, Y,  Allweis, T., Freund, H.R. and  Hanani, M. Bacterial wall lipopolysaccha­ride as a cause for intussusception in  mice.   J. Pediatr. Gastroenterol. Nutr. 27:301-305, 1998.

 

70. Hanani, M.  Interstitial cells of Cajal -- the pacemaker cells  of the gastrointestinal system. Harefuah  136:307-312, 1999 (in Hebrew).

 

71. Nissan, A., Maudlej, N., Beglaibter, N., Haskel, Y., Freund H.R. and  Hanani, M. A direct inhibitory effect of erythromycin on rat urinary bladder smooth muscle.

J. Urology, 161:1006-1009, 1999

 

72. Hanani, M., Maudlej, N. and  Härtig, W.   Morphology and intercellular communication in  glial cells of  the intrinsic ganglia of the guinea-pig urinary bladder. J. Auton. Nervous System, 76:62-67, 1999.

 

73. Hanani, M. Introduction to interstitial cells of Cajal.  Microscopy Res. Tech. 47:221-222, 1999.

 

74. Hanani, M. and Belzer, V., Rich A., and Faussone-Pellegrini S.M. Visualization of interstitial cells of Cajal  in intact tissues.  Microscopy Res. Tech. 47:336-343, 1999.

 

75. Hanani, M.,   Francke, M.,   Härtig, W., Grosche, J.,  Reichenbach, A., and  Pannicke, T.  A patch clamp study of neurons and glial cells in isolated myenteric ganglia. Am. J. Physiol. 278:G645-G651, 2000.

 

76. Ermilov, L.G.,  Miller, S.M., Hanani, M., Schmalz, P.F. and Szurszewski, J.H.   The three-dimensional structure of the guinea-pig inferior mesenteric and pelvic-hypogastric ganglia.  Autonomic Neuroscience, 83:116-126, 2000.

 

77. Hanani,  M. and Freund H.R. Interstitial cells of Cajal -- their role in pacing and signal transmission in the digestive system.  Acta Physiol Scand. 170:177-190, 2000.

 

78. Hanani, M. and Brading, A.F. Electrical coupling among smooth muscle cells, is it universal?   J. Basic Clin. Physiol.  Pharmacol.   11:321-330, 2000.

 

79 Haskel, Y., Udassin, R., Zhang, J.M., Hanani, M. and Freund, H.R. Liquid enteral diets induce bacterial translocation by increasing enteral flora without changing intestinal motility. JPEN J. Parenteral Enteral Nutrition, 25:60-64, 2001.

 

80. Belzer, V., Kobilo, T., Rich A. and Hanani M. Intercellular Coupling among interstitial cells of Cajal in the guinea-pig small intestine.  Cell Tissue Res. 307:15-21, 2002.

 

81. Freund, H.R. and Hanani, M.  The metabolic role of branched-chain amino acids. Nutrition. 18:287-288, 2002.

 

82. Rich, A.,  Hanani M., Ermilov, L.G., Malysz, J., Belzer, V.,  Szurszewski, J.H., Farrugia, G.   Physiological study of interstitial cells of Cajal identified by vital staining. Neurogastroenetrol Motil. 14:189-196, 2002.

 

83.  Nissan, A., Freund, H.R., and Hanani, M.  Direct inhibitory effect of erythromycin on human alimentary tract smooth muscle.  Am. J. Surgery  183:413-418, 2002.

 

84.   Hanani M., Huang, T.Y., Cherkas P.S., Ledda, M., Pannese E. Glial cell plasticity in sensory ganglia induced by nerve damage.   Neuroscience,  114:279-283, 2002.

 

85. Pannese, E., Ledda, M., Huang, T.Y.,  Cherkas, P.S.,  Hanani, M. Satellite cell reactions to axon injury of sensory ganglion neurons: increase in number of gap junctions and formation of bridges connecting previously separate perineuronal sheaths.  Anat. Embryol., 206:337-347, 2003. 

 

86.  Ermilov, L.G., Schmalz, P.F. Miller, S.M., Hanani, M., Lennon, V.A. and Szurszewski, J.H. Morphological characteristics and immunohystochemical  detection of  nicotinic acetylcholine receptors in intestinofugal afferent neurons of the guinea-pig colon.   Neurogastroenterol Motil, 15:289-298, 2003.

 

 87. Hanani, M., Ledder, O., Yutkin, V., Abu-Dalu, R , Huang, T.Y.,   Härtig, W., Vannucchi, M.G. and Faussone-Pellegrini, M.S. Regeneration of myenteric plexus in the mouse colon after experimental denervation with benzalkonium chloride.  J Comp. Neurol. 462:315-327, 2003.

 

88. Weick, M.,  Cherkas, P.S., Härtig, W. , Pannicke, T., Uckermann, O., Bringmann, A., Tal, M., Reichenbach, A., and Hanani, M.   P2 Receptors in satellite glial cells in trigeminal ganglia of mice.  Neuroscience 120:969-77,  2003.

 

89. Kobilo, T.,  Szurszewski, J.H., Farrugia, G.,  Hanani, M.  Coupling and innervation patterns of interstitial cells of Cajal in the deep muscular plexus (ICC-DMP) of the guinea-pig.  Neurogastroenterol Motil., 15:1-7, 2003.

 

90.  Braun, N.,  Sévigny, J.,  Robson. S.C., Hammer, K., Hanani, M., and Zimmermann, H. Association of the Ecto-ATPase NTPDase2 with glial cells of the peripheral nervous system. Glia 45:124-132, 2004.

 

91. Belzer, V.,  Nissan, A., Freund, H.R.  Hanani, M. Coupling among interstitial cells of Cajal in the human ileum. Neurogastroenterol. Motil., 16:75-80, 2004.

 

92. Hanani, M. Multiple myenteric networks in the human appendix. Auton. Neurosci. 110:49-54, 2004.

 

93.  Reichenbach, A., Derouiche A., Grosche, J. and Hanani, M.  Structural association of glia with the various specialized compartments of neurons. In: Hatton, G.I. & Parpura, V. (eds),  Neuron Glia Interactions, Kluwer Publishers,  53-97, 2004.

 

94. Bar-Shai, A., Maayan, C., Vromen, A.,  Udassin, R., Nissan, A.,  Freund, H.R., Hanani, M.  Decreased density of ganglia and neurons in the myenteric plexus of familial dysautonomia patients.  J. Neurol. Sci. 220:89-94, 2004.

 

95. Cherkas, P.S.,  Huang, T.Y.,  Pannicke, T., Tal, M., Reichenbach, A., Hanani, M.  The effects of axotomy on neurons and satellite glial cells in mouse trigeminal ganglion. Pain, 110: 290-298, 2004.

 

96. Hanani, M.,  Fellig, Y., Udassin, R., Freund, H.R. Age-related changes in the morphology of the myenteric plexus of the human colon. Autonomic Neuroscience, 113:71-78, 2004.

 

97. Hanani, M., Farrugia, G., Komuro, T. Intercellular coupling among interstitial cells of Cajal in the digestive tract. Int. Rev. Cytol. 242:249-282, 2005.

 

98. Huang, T.Y., Cherkas, P.S., Rosenthal, D.W., Hanani, M. Dye coupling among satellite glial cells in mammalian dorsal root ganglia. Brain Res. 1036:42-49, 2005.

 

99. Hanani, M. Satellite glial cells in sensory ganglia: from form to function. Brain Res. Rev. 48:457-476, 2005.

 

100. Huang, T.Y. Hanani, M.  Morphological and Electrophysiological Changes in Mouse Dorsal Root Ganglia after Partial Colonic Obstruction. Am. J. Physiol. Gastrointest. Liver Physiol.   289:G670-G678, 2005.

 

101. Huang TY,  Hanani M,  Ledda M, De Palo S,  Pannese E. Aging is associated with an increase in dye coupling and in gap junction number in satellite glial cells of murine dorsal root ganglia. Neuroscience 137:1185-1192, 2006.

 

102.  Faussone-Pellegrini, M.S.,  Vannucchi, M.G., Ledder, O., Huang, T.Y., Hanani, M. Interstitial cells of Cajal plasticity: A study in the mouse colon Cell Tiss Res (in press).

 

Invited Commentary

 

Hanani, M. and Rachmilewitz, D.  Commentary on: Tomita, R. and Tanjoh, K. Role nitric oxide in the colon of patients with ulcerative colitis. World J. Surg. 22:93, 1998.

 

Popular Science

 

Hanani M. Why NO? (The biology of nitric oxide), Galileo No. 30, 22-26, 1998 (in Hebrew)

 

Hanani, M.   A crisis in science? (on the peer review system), Galileo No. 53, 42-46, 2003 (in Hebrew).

 

Co-Editor of a Book

 

Feigenbaum, J.J. and Hanani, M. (editors):‚ Presynaptic Regulation of Neurotransmitter Release: a Handbook.‚ Freund Publishing Co., London and Tel Aviv, 1991.  The book  consists  of  48 chapters by leading scientists from 12 countries.  It  contains  1400 pages in 3 volumes and includes a 43-page index.

 

Guest Editor

 

Microscopy Research and Technique, Vol. 47, 1999, issues number 4 and 5 dedicated to the topic: “Interstitial Cells of Cajal”.

 

Abstracts

 

1. Hanani, M.  and  Hillman, P. A mechanism for light and dark adaptation  in  the  barnacle photoreceptor. Israel  J. Med. Sci. 11: 76, 1975.

 

2. Hanani, M. and Hillman, P. Regulation of sensitivity to light by two antagonistic processes in the barnacle photoreceptor. Israel J. Med. Sci. 11: 858, 1975.

 

3. Hanani, M.  and  Hillman, P. Facilitation in the barnacle photoreceptor. Abstracts of  the ARVO Symposium, Sarasota, Florida, April 1975.

 

4. Hanani, M.  Visual adaptation at the receptor level. Abstracts of the ISERG Symposium, Ginossar, Israel, April 1975.

 

5. Hanani, M. Calcium-induced increase in potassium conductance in photoreceptors.  Israel  J. Med. Sci. 12: 1218, 1976.

 

6. Hanani, M. and Hillman, P. Role of pigment transfer in facilitation in the barnacle  photo­receptor.  Israel J. Med. Sci.  12: 1512, 1976.

 

7. Hanani, M.  and  Fein, A. Discrete wave frequency increases after bright illumination in Limulus ventral photoreceptors.  Biol. Bull. 152: 428, 1977.

 

8. Hanani, M. and Hillman, P. Pigment influences on adaptation-facilitation balance in barna­cle photoreceptor. Proc. Int. Union Physiol. Sci. 13: 363, 1977.

 

9. Hanani, M.  and Fein, A. Post-stimulus increase of discrete wave frequency in Limulus photoreceptors. Biophysical J. 21: 117a, 1978.

 

10. Vallerga,  S.  and  Hanani, M. Rod and cone contribution to horizontal cell responses.  Abstracts of the ARVO Symposium, Sarasota, Florida, April 1978.

 

11. Hanani, M. and  Fein,  A. Discrete wave frequency in Limulus photoreceptors  increases after  bright illumination. Abstracts of the ARVO Symposium, Sarasota, Florida,  April 1978.

 

12. Hanani, M.  and Fein, A. A dual effect of diamide, a thiol oxidizing agent,  on  the  photoresponse of the Limulus ventral eye. Biol. Bull., 153, 1978.

 

13. Hanani, M. and Hillman, P. Pigment transitions and facilitation in the  barnacle  photorereceptor. Neuroscience Letters  Suppl. 6: 406, 1978.

 

14. Hanani, M.  and  Vallerga, S. Rod and cone inputs to retinal horizontal cells. Israel J. Med. Sci., 15: 949-950, 1979.

 

15. Shaw,  C., Hanani, M. and Hillman, P. Does alcohol mimic effects of light on bump  rate  Limulus ventral photoreceptors? Israel J. Med. Sci. 15: 952, 1979.

 

16. Normann, R.A., Kolb, H., Hanani, M., Pasino, E. and Holub, R. Orientation  sensitivity  of  horizontal cells in the visual streak. Abstracts of the ARVO  Symposium,  Sarasota,  Florida, April 1979.

 

17. Hanani, M.  and  Fein,  A. Effects of diamide on the light  response  of  Limulus  ventral  photoreceptors. Israel J. Med. Sci. 16: 614, 1980.

 

18. Shaw,  C.,  Hanani, M., Atzmon, Z. and Hillman, P. The effects of alcohol  on  receptor potentials,  adaptation and discrete wave rate in invertebrate  photoreceptors.  Abstracts of the ARVO Symposium, Orlando, Florida, April 1980.

 

19. Hanani, M., Baluk, P. and Burnstock, G. Electrophysiology and morphology of myenteric neurons in tissue and culture. Neuroscience Letters Suppl. 10: S231, 1982.

 

20. Vinograd,  I., Hanani, M., Hadary, A. and Nissan, S. An animal model for  studying  the physiology and pharmacology of the anal sphincter. Israel J. Med. Sci., 19: 100, 1983.

 

21. Hanani, M.,  Chorev,  M.,  Gilon, C. and Selinger, Z. The effects of receptor-specific substance P analogs on myenteric neurons. Rev. Clin. Basic Pharmacol. 6:252, 1987.  

 

22. Bauer,  A.J.,  Muir,  T.C.,  Hanani, M. and Szurszewski, J.H. Cholecystokinin (CCK)  modulates  synaptic  transmission  in intramural ganglia of  opossum  gallbladder.  Dig. Dis. Sci. 32: 902, 1987

 

23. Hanani, M.   A.J.  Bauer and J.H. Szurszewski. Electrophysiology and morphology  of  the intrinsic neurons of the opossum gallbladder. Rev Clin. Basic Pharmacol. 6:362, 1987.

 

24. Selinger,  Z.,  Laufer,  R., Chorev, M., Gilon, C. and Hanani, M. Tachykinin receptor-selective  analogs-ionic mechanism and specific behavioral effects.  Regul. Peptides. 22:170, 1988.

 

25. Hanani, M. and Zamir, O. Dye-coupling among intestinal smooth muscle cells. Pfluegers Arch. 413: R34, 1989.

 

26.  Hanani, M., Madlag, N., Baluk, P. and Zamir, O. Dye-coupling among cells in  gan­glia that innervate the GI tract. J. Gastroint. Motil. 1:70, 1989.

 

27. Hanani, M. and Zamir, O. Evidence for dye coupling among longitudinal  smooth  muscle  cells in the small intestine.  J. Gastroint. Motil. 1:70, 1989.

 

28. Hanani, M.  and  Zamir,  O. Dye coupling study of intestinal smooth muscle cells.  The  Physiologist 32:176, 1989.

 

29.  Hanani, M.  and  Wood, J.D. Corticotropin  releasing  hormone  (CRH)  simulates slow synaptic excitation in the myenteric plexus. Gastroenterology 98:357A, 1990.

 

30. Miller,  S.  Hanani, M., Geddes, R. and Szurszewski, J.H. Projections of neurons in the superior mesenteric ganglion revealed by intracellular labeling with horseradish peroxidase. Gastroenterology 100: A470, 1991.

 

31. Christofi, F.L. Hanani, M. and Wood, J.D. Use of cytosine arabinoside to assess neuronal and glial cAMP in adult myenteric cultures. Gastroenterology 100: A429, 1991.

 

32. Hanani, M. and Wood, J.D. Cultured myenteric ganglia from the adult guinea-pig: developmental, morphological and electrophysiological characterization.  J.  Gastroint. Motil. 3:183, 1991.

 

33. Hanani, M.,  Udassin,  R., Ariel, I. and Freund, H.R. Vital fluorescent staining of the enteric  nervous system (ENS): clinical and research applications. J.  Gastroint.  Motil. 3:183, 1991.

 

34. Hanani, M. and Wood, J.D. Neuron-glia interactions in cultured myenteric ganglia  from adult guinea-pigs. J. Basic Clin. Physiol. Pharmacol. Suppl.  2/3:B45, 1992.

 

35. Maudlej,  N. and Hanani, M. Dye coupling among glial cells in autonomic ganglia and  its modulation. J. Basic Clin. Physiol. Pharmacol. Suppl. 2/3:B46, 1992.

 

36. Maudlej,  N.  and  Hanani, M.  electrophysiological study of intramural neurons in the  guinea-pig urinary bladder. J. Basic Clin. Physiol. Pharmacol. Suppl.  2/3:34, 1992.

 

37. Hanani, M., Louzon, V., Vromen, A., Udassin, R. and Freund H.R. NADPH-diaphorase staining of enteric neurons in the human colon. J. Gastoint. Motil.  5:195, 1993.

 

38. Miller, S., Hanani, M., Schmalz, P. and Szurszewski, J.H. Three dimensional reconstruc­tion  of  VIP innervation of smooth muscle of the mouse large  intestine.  J.  Gastroint. Motil. 5:206, 1993.

 

39. Hanani, M.,  Miller, S.M. and Szurszewski, J.H. Confocal microscopic study of the innervation of  single intestinal smooth muscle cells. Abstracts of the second annual meeting of  the Israel Neuroscience Society, Eilat, 34, 1993.

 

40. Hanani, M., Louzon, V., Udassin, R., Freund, H.R., Karmeli, F. and Rachmilewitz,  D. Nitric oxide in Hirschsprung's disease. Gastroenterology 106:A507, 1994.

 

41. Hanani, M. and Reichenbach, A. Morphometric and fractal analysis of glial cells  in  the myenteric  plexus.  Abstracts  of  the  third annual meeting of the Israel  Neuroscience Society, Eilat, 18, 1994.

 

42. Hanani, M., Nissan, A., Mashriki, Y., Zhang, J.M., Haskel, Y. and Freund, H.R. Direct inhibitory action of erythromycin on the gallbladder muscles. Gastroenterology 108:A1222, 1995.

 

43. Hanani, M. and Lasser-Ross, N. Combined electrical and calcium transient measurements in guinea-pig myenteric neurons. Neurogastroenterol. Motil. 7:262, 1995.

 

44. Louzon,  V.  Miller,  S.M.  and  Hanani, M. Visualization of  interstitial cells of  Cajal  (ICC's) in living tissues. Neurogastroenterol. Motil. 7:271, 1995.

 

45. Louzon,  V.,  Lin,  Z.  and Hanani, M. Phorbol esters alter the morphology of  cultured enteric glia. Israel J. Med. Sci. 31:754, 1995.

 

46. Maudlej, N. and Hanani, M. The effect of substance P (SP) analogs on intramural neurons in the guinea-pig urinary bladder. Israel J. Med. Sci. 31:761, 1995.

 

47. Granovsky-Grisaru, S., Dan, I., Lavie, O., Abulafia Y.,  Diamant, Z.Y. and Hanani, M. Effects  of  erythromycin  on contractility of isolated myometrium  from  pregnant  rats. Am. J. Obstset. Gynecol. 74:482, 1996. 

 

48. Hanani, M., Nissan, A., Lin, Z., Cohen, P. and Freund H.R. Introduction of  intussusception   in  mice  by  intraperitoneal  injection  of   lipopolysaccharide.   Gastroenterology 110:A1389, 1996.

 

49. Nissan,  A.,  Hanani, M.,  Mashriki, Y.,  Zhang, J.M.,  Haskel,  Y.  and  Freund,  H.R. Direct inhibitory effect of erythromycin on human gastrointestinal tract smooth  muscle. Gastroenterology, 110:A1407, 1996.

 

50. Ermilov, L.G., Hanani, M. Miller, S.M., Szurszewski, J.H. Three dimensional  morphol­ogy  of neurons of the "colon-inferior mesenteric ganglion" reflex  pathway.  Gastroen­terology, 110:A660, 1996

 

51. Hanani, M.  and Lasser-Ross, N. Characterization of myenteric neurons  by  simultaneous electrical and calcium measurements. Isr. J. Med. Sci. 32:S42, 1996.

 

52. Miller, S.M, Ermilov, L.G., Hanani, M.., and  Szurszewski, J.H. The neuritic processes of Dogiel type II colonofugal neurons are arranged parallel to the circular muscle layer of the mouse colon.  Gastroen­terology, 112:A789, 1997.

 

53. Hanani, M.,  Lin,  Z.,  Louzon, V, Brenner, T. and Boneh, The morphology of cultured myenteric glia is altered by phorbol  esters. Gastroenterology 112:A744, 1997.

 

54. Neuhaus, J., Hanani, M., Maudlej, N. and Dorschner W. Comparative study on the morphology and immunocytochemistry of lower urinary tract autonomic ganglia. Soc. for Neurosci. Abst. 23:1051, 1997.

 

55. Kachalsky, S.G., Ivancheva, C., Radomirov, R., Rahamimoff, R. and Hanani, M. Calcium confocal imaging of isolated myenteric ganglia. Isr. J. Med Sci. 33:830, 1997.

 

56. Rosenthal, D., Cherkas, P. and Hanani, M.  Satellite glial cells in the mammalian dorsal root ganglion are dye coupled. Neuroscience Letters Suppl. 48:S42, 1997.

 

57. Hanani, M., Francke, M., Kachalski, S., Rahamimoff, R. and A. Reichenbach. Patch recordings and confocal microscopic Ca2+  imaging in isolated myenteric ganglia. Neurogastroenterol Motil 10:74, 1998.

 

58. Ermilov, L.G., Hanani, M., Schmalz, P.F. Miller, S.M. and Szurszewski, J.H. Distribution of nicotinic receptors in intestinofugal neurons of the guinea-pig.   Neurogastroenterol Motil 10:69, 1998.

 

59. Fellig, Y., Vromen, A., Udassin, R., Freund, H.R. and Hanani, M.  Age related changes in the myenteric plexus of the human colon.   Neurogastroenterol Motil 10:72, 1998.

 

60. Faussone-Pellegrini, M.S., Louzon, V., Miller, S.M. and Hanani, M. Ultrastructural visualization of interstitial cells of Cajal in the mouse colon with vital staining.  Neurogastroenterol Motil 10:71, 1998.

 

61. Hanani, M.  and Gross,  A. Imaging of myenteric neurons in the intact intestine of living animals.  Neurogastroenterology and Motility 10:74, 1998.

 

62. Fellig, Y., Vromen, A., Udassin, R., Freund, H.R. and Hanani, M. The morphology of myenteric plexus of the human colon is altered with age. Gastroenterology 114:S0042, 1998.

 

63. Cherkas, P.S. and Hanani, M. Axotomy induces extensive coupling among cells in sensory ganglia. Neuroscience Letters Suppl. 51:S10, 1998.

 

64. Rich, A., Ermilov, L.G.,  J., Hanani, M., V., Farrugia, G. and Szurszewski, J.H. Confocal imaging of interstitial cells of Cajal in the guinea-pig small intestine. Gastroenterology 116:A1070, 1999.

 

65. Francke, M., Hanani, M. Pannicke T. and Reichenbach, A.  Patch clamp recordings from glia and neurons in freshly isolated myenteric ganglia.  In Goettingen Neurobiology Report. Proc. of the 1st Goettingen Conference of the German Neuroscience Soc., Vol. 2, N. Elsner and U. Eysel,  eds. p. 720, Stuttgart, Thieme, 1999.

 

66. Rich, A., Ermilov, L.G., Malysz. J., Hanani, M., Schmalz, P.F., Belzer, V., Farrugia, G. and Szurszewski, J.H. Electrical recording from interstitial cells of Cajal in the myenteric region of the guinea-pig small intestine. Neurogastroenterol Motil, 11:285, 1999.

 

67. Ermilov, L.G., Rich, A., Hanani, M., Schmalz, P.F., Belzer, V., Farrugia, G. and Szurszewski, J.H. Three-dimensional visualization of interstitial cells of Cajal in the myenteric region of the guinea-pig small intestine. Neurogastroenterol Motil, 11:260, 1999.

 

68. Belzer, V. and Hanani, M.  Dye coupling among interstitial cells of Cajal and its modulation.  Neurogastroenterol Motil, 11:250, 1999.

 

69. Hanani, M., Cherkas, P. and Tal, M. Axotomy induces changes in cell coupling in the mouse trigeminal ganglion.  Neuroscience Lett. Suppl. 54, S19-S20, 1999.

 

70. Efron, L., Hanani, M., Gilon C. The use of reduced pseudodipeptides as building units for backbone cyclization: synthesis and incorporation into the C-terminal backbone cyclic hexapeptide analogs of substance P. Peptides 25:488-499, 1999.

 

71. Hanani, M. Calcium dynamics in myenteric neurons. Autonomic Neuroscience 82: 67, 2000.

 

72. T.  Huang , P.  Cherkas and M.  Hanani. Glial dye coupling changes  with  age  in sensory  ganglia.  Neuroscience Lett. Suppl. 55:S25, 2000.

 

73. Kobilo, T. and Hanani, M. The innervation of intestinal smooth muscle cells: a quantitative study.  Neuroscience Lett. Suppl. 55:S29, 2000.

 

74. Zardo, C., Huang, T., Hanani, M. Faussone-Pellegrini, M.S. Light- and electron-microscopic study of re-innervation process in the mouse colon after experimental denervation . Ital. J. Anat. Embryol. 106:suppl. 1, 277, 2001.

 

75. Kobilo, T., Belzer, V. and Hanani, M.   Coupling and innervation pattern of  interstitial cells of Cajal and its modulation.  Neurogastroenterol Motil, 13:406, 2001.

 

76. Hanani, M., Ledder, O., Vannucchi M.G., Faussone-Pellegrini, M.S. Light- and electron-microscopic study of nerves and ICC in the mouse colon after the acute phase of experimental denervation.  Neurogastroenterol Motil, 13:395, 2001.

 

77. Belzer, V. and Hanani, M. Coupling among  interstitial cells of Cajal (ICC) in the human small intestine.  Neurogastroenterol Motil, 13:373, 2001.

 

78. Huang, T.Y. and Hanani, M.  Changes in morphology and electrophysiology of neurons and glial cells in mouse sensory ganglia following partial obstruction of colon. Neural Plasticity 8:179, 2001.

 

79. Huang, T.Y, Hanani, M. Partial colonic obstruction alters the morphology and electrophysiology of neurons and glial cells in mouse sensory ganglia. Gastroenterology 122:A-25, 2002.

 

80. Huang TY,  Hanani, M., Cherkas, P.S., Ledda, M. and Pannese E.  Glial cell coupling and growth in sensory ganglia after axotomy: ultrastructural evidence. Neural Plasticity 9:91, 2002.

 

81.  Cherkas, P.S., Weick, M., Hartig, W.,  Pannicke, T., Huang, T.Y. Tal, M., Reichenbach, A.,  and  Hanani, M.  P2Y4 receptors in trigeminal ganglia of mice. Neural Plasticity 9:78, 2002.

 

82. Ermilov, L.G., Hanani, M., Schmalz, P.F. Miller, S.M., Lennon, V.A. and Szurszewski, J.H.  Characterization of  intestinofugal afferent neurons of guinea-pig colon.   Neurogastroenterol  Motil 14:427, 2002.

 

83. Hanani, M. Huang, T.Y., Cherkas, P.S., Ledda, M., Pannese, E. (2002)  Glial cell plasticity in sensory ganglia induced by nerve damage. FENS  Abstr. vol. 1, A050.9.

 

84. Cherkas PS, Weick M, Härtig W, Bringmann A, Tal M, Reichenbach A, Hanani M, Pannicke T. (2003) P2 receptors in satellite glial cells in trigeminal ganglia of mice.  Proceedings of the 29th Göttingen Neurobiology Conference and the 5th Meeting of the German Neuroscience Society 2003.  (Elsner N,  Zimmermann H, eds.) Georg Thieme Verlag, Stuttgart, Nr. 220, p. 330-331.

 

85. Hanani, M.,  Ledder, O.,  Huang, TY, Vannucchi, M.G.,  Faussone-Pellegrini, M.S. (2003) Plasticity and neurogenesis in the adult myenteric plexus following injury. Neurogastroenterol. Motil. 15:10.

 

86. Hanani, M. (2003) An unusual arrangement of the myenteric ganglia in the human appendix.  Neurogastroenterol. Motil. 15:11.

 

87. Hanani, M. and Huang, T.Y. (2004)  Contribution of gap junctions in sensory ganglia to inflammatory pain. FENS  Abstr. vol. 2, A121.7.

 

88. Hanani, M.  and Huang T.Y. (2005) Gap junctions in sensory ganglia contribute to visceral pain. Rev Neurosci 16: suppl. 1:S29.

 

 

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Prof. Menachem Hanani


            
     
 


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