1963 Born, Israel
Education
1984: B.M.S., Hebrew University , Israel
1987: DMD., Hebrew University , Israel
1993-1996: Post-graduate program, specializing in Orthodontics, Tel Aviv University , Israel
1997: Specialist in Orthodontics , Israel
1997: Clinical Instructor, Tel Aviv University , Israel
2000: Visiting Lecturer, Harvard University , USA
2002: Director, Predoctoral Orthodontics, Harvard University , USA
2002: Director, Postdoctoral Orthodontic Clinic, Harvard University , USA
2002: Instructor, Harvard University, USA
2004: Assistant Professor of Oral and Developmental Biology (Orthodontics), Harvard School of Dental Medicine, Harvard University, USA
Research
The future of the field of Orthodontics depends on our ability to adopt new research methodologies combining clinical orthodontics with genetics and applying them to advance orthodontic research into new bold areas. Along this line, my research has been progressing in two paths: clinical studies and basic science:
I. Clinical Research
We have established a new dental anomaly, expressed in a distal inclination of the mandibular second premolar (MnP2). We have shown clear associations between this anomaly and various other dental anomalies already established to be of genetic origin. By that we have shown the genetic trait of this anomaly, suggesting several genes as possible causes. At present, we continue collecting data to study association with other known anomalies and also to build a data base for classification of the MnP2 distalation anomaly.
II. Basic Science Research
Genetic influences in bone remodeling. In this study, we use orthodontic tooth movement in mice to induce bone remodeling. Our model is based on the histological comparison of orthodontically induced bone remodeling between wild-type mice and mutant mice, in which a certain gene has been “knocked out.” This model should help us understand the role of this specific gene in the process of bone remodeling, which is the basic natural process enabling the orthodontic treatment.
Publications
Shalish M, Chaushu S, Wasserstein A. Malposition of unerupted mandibular second premolar in children with palatally displaced canines. Angle Orthod 2009;79:796-9.
Shalish M, Will LA, Shusterman S. Malposition of unerupted mandibular second premolar in children with cleft lip and palate. Angle Orthod, 2007;77:1062–6.
Wasserstein A, Brezniak N, Shalish M, Heller M, Rakocz M. Angular changes and their rates in concurrence to developmental stages of the mandibular second premolar. Angle Orthod, 2004;74:332-6.
Wasserstein A, Shalish M. Adequacy of mandibular premolar position despite early loss of its deciduous molar. ASDC J Dent Child, 2002;69:254-8.
Shalish M, Peck S, Wasserstein A, Peck L. Malposition of unerupted mandibular second premolar associated with agenesis of its antimere. Am J Orthod Dentof Orthop, 2002;121:53-6. Selected as Editor's choice
Haisraeli-Shalish M, Livne A, Katz J, Doolman R, Sela B-A. Recurrent aphtous stomatitis and thiamine deficiency. In Yearbook of Dentistry, Meskin LH., Berry TG, Jeffcoat MK, Leinfelder KF. Roser SM, Summitt JB, Zakariasen KL (Eds.), Mosby, St. Louis , 1998, pp.151-2.
Haisraeli-Shalish M, Livne A, Katz J, Doolman R, Sela B-A. Recurrent aphtous stomatitis and thiamine deficiency. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 1996; 82:634-6.
Deutsch D, Haisraeli M, Palmon A, Arad A, Alayoff A. Separation, purification and characterization of enamel proteins using HPLC, 2D electrophoresis and specific polyclonal antibodies. In Current Advances in Skeletogenesis/3, S. Hurwitz and J. Sela (Eds.) Heiliger Publ. Co., Jerusalem , 1986, pp.169-75.
Deutsch D, Haisraeli M, Palmon A, Arad A, Alayoff A. Separation, Purification and Characterization of Enamel Proteins, using HPLC, 2D-Electrophoresis, Limited Proteolysis and Specific Polyclonal Antibodies. Bone, 1986; 7 (5): 408-408.