Reproductive Endocrinologist,

Infertility and Menopause Specialist
Department of Obstetrics and Gynecology

Hadassah University Hospital

Mount Scopus, Jerusalem
E-mail: kochman@hadassah.org.il

Fax: (02) 581-4210

Born in Tel Aviv, 1965

Married with 3 children

Graduate of the Hebrew University -Hadassah Medical School 1989

Residency in Obstetrics and Gynecology, Dept of Obstetrics and Gynecology, Hadassah Mt. Scopus 1995-2000

Board certified in Obstetrics and Gynecology since 2000

Fellowship: Placental biology (basic research), University of California, San Francisco 2003-2004

2000 to date: Senior physician in Obstetrics and Gynecology, Hadassah University Hospital, Mt. Scopus, Jerusalem, Israel.

2004 to date: In charge of teaching program of 5th year medical students, Department of Obstetrics and Gynecology,  Hadassah, Mt Scopus.

2006: Senior lecturer in Obstetrics and Gynecology, Faculty of Medicine of the Hebrew University - Hadassah Medical School, Jerusalem, Israel.    

At Hadassah

Reproductive endocrinologist; staff physician at the In Vitro Fertilization unit and the menopause clinics.

Research

Basic Research: Molecular biology of the placenta; immuno surveillance at the maternal fetal interface; mechanisms of implantation, ovulation and corpus luteum formation.

Clinical Research: Infertility, menopause and contraception

Awards and Distinctions

1983-1986       B.Sc. in Medical Sciences. Cum Laude.

Dean’s Award, Hebrew University.

Annual Scholarship for academic excellence.

1990 - Certification of the "Educational Commission for Foreign Medical Graduates".

Annual scholarship for academic excellence

1990 - Graduation of the officers' academy of the Israeli Defense Forces in  excellence

2002 - Award for the best clinical study " Characterization of the optimal method of discontinuation of hormonal replacement therapy" at the 5th annual meeting of the Women's Health Society, Tel-Aviv, Israel

2003 - Award for the best abstract "Expression of heparanase in murine and human corpus luteum" at the annual meeting of the Israeli Society for Fertility Investigation, Tel-Aviv, Israel

Dean's Teaching Award, Hebrew University

Research Grants

2000 -  $10,000 grant. Hadassah Medical Organization: Localization of heparanase in normal and pathological human placenta- an immuno histochemistry study. (with Dr. Zehava Rengini)

2002 - $20,000. Hadassah Medical Organization: The role of heparanase in morphogenesis, angiogenesis and sprouting of murine and human villous placentae. (with Dr. Reuven Reich)

2002 - 100,000 NIS. The Israeli Ministry of Health, Chief Scientist.  Grant: The role of heparanase in morphogenesis, angiogenesis and sprouting of murine and human villous placentae. (with Dr. Reuven Reich)

2004 - $20,000. Hadassah Medical Organization physician-scientist grant: Hypoxia regulation of heparanase in the murine and human placenta.

2005 -  $10,000. Keren Meshutefet. Expression and Localization of Heparanase in Various Stages of Endometrial Hyperplasia-Carcinoma Continuum. (Advisor, with Dr. Ahinoam Lev-Sagie, Dr. Inbar Ben-Shahar)

2005 - 30,000 NIS. Hadassah Medical Organization compensatory fund. Hypoxia regulation of heparanase in the murine and human placenta.

2005 - $20,000. Hadassah Medical Organization. Expression and Localization of Heparanase in Various Stages of Endometrial Hyperplasia-Carcinoma Continuum. (Advisor, with Dr. Ahinoam Lev-Sagie, Dr. Inbar Ben-Shahar and Dr. Haya Galski-Lorberbaum)

Participation in Societies

§         Member of the Israel Menopause Society (from 2000).

§         Member of the Israeli Society of Fertility and Reproduction (from 2000).

§         Member of the Israeli Society of Contraception and Sexual Health (from 2002).

§         Member of the Society of Gynecologic Investigation (from 2003)

Reviewer of International Academic Journals

§         Human Reproduction

§         Medical Science Monitor

List of publications (updated 1-2006)

1. Amitai Y, Gillis D, Wasserman D, Kochman RH. Henoch-Schonlein purpura in infants. Pediatrics. 1993;92:865-7.

2. Haimov-Kochman R, Ackerman Z, Anteby EY. The contraceptive choice for a Wilson's disease with chronic liver disease. Contraception. 1997;56:241-4.

3. Haimov-Kochman R, Laufer N, Milwidsky A. Cesarean section for severe fetal distress in a woman with diabetic ketoacidosis. Israel Journal of Obstetetrics and Gynecology. 1998;9:164-7.

4. Haimov-Kochman R and Ben-Chetrit E. The effect of colchicine treatment on sperm production and function: a review. Human Reprodroduction. 1998;13:360-2.

5. Haimov-Kochman R, Bromiker R, Milwidsky A. Prevention of perinatal group B streptococcus disease in light of an unknown maternal carriage rate in Israel. Harefuah. 2000;138:1040-3.

6. Haimov-Kochman R, Lavy Y, Prus D. False positivity of CA-125 in a case of Struma Ovarii and ascites. Israel Journal of Obstetetrics and Gynecology. 2000;11:16-7.

7. Haimov-Kochman R and Yagel S.  The ultrasound markers of the anauploid fetus in the first and second trimesters of pregnancy. Harefuah. 2001;140:531-40.

8. Haimov-Kochman R, Prus D, Ben-Chetrit E. Azoospermia due to testicular amyloidosis in a patient with familial Mediterranean fever. Human Reprodroduction 2001;16(6):1218-20.

9. Haimov-Kochman R, Friedmann Y, Prus D, Goldman-Wohl DS, Greenfield C, Anteby   EY, Aviv A, Vlodavsky I, Yagel S. Localization of heparanase in normal and pathological human placenta. Mol Hum Reprod 2002;8(6):566-73.

10. Haimov-Kochman R, Sciaky-Tamir Y, Yanai N, Yagel S. Conservative management of two ectopic pregnancies implanted in  previous uterine scars. Ultrasound Obstet Gynecol 2002;19(6):616-

11. Haimov-Kochman R, Lavy Y, Hochner-Celinkier D. Review of risk factors for breast cancer - What’s new? Harefuah 2002;141(8):702-708.

12. Haimov-Kochman R, Doviner V, Amsalem H, Prus D, Adoni A, Lavy Y. Intraperitoneal

levonorgestrel releasing intrauterine device following uterine perforation : the role of progestins in adhesion formation. Human Reprod 2003;18(5):990-993.

13. Hanna J, Wald O, Goldman-Wohl D, Prus D, Markel G, Kats G, Mizrahi S, Haimov-Kochman R, Nakamura F, Yagel S, Peled A, Mandelboim O. CXCL12 expression by invasive trophoblasts induces the specific migration of CD16 negative natural killer cells. Blood 2003:102(5):1569-1577

14. Haimov-Kochman R, Amsalem H, Adoni A, Lavy Y, Spitz MI. Management of a perforated levonorgestrel-medicated intrauterine device – a pharmacokinetic study- Case report.
Hum Reprod 2003;18(6):1231-3.

15. Haimov-Kochman R, Kochman T, Stabholz A, Hochner-Celinkier D. Clinical  periodontitis during menopause, a possible role for bisphosphonate and estrogen replacement therapy.  IMAJ 2004:6:173-7.

16. Goldman-Wohl D, Greenfield C, Haimov-Kochman R,  Ariel I, Anteby EY, Hochner-Celinkier D, Farhat M, Yagel S. Eph and ephrin expression in normal placental development and preeclampsia. Placenta 2004:25(7):623-30.

17. Haimov-Kochman R, Yanai N, Amsalem H, Lavy Y, Hurwitz A. Ovarian hyperstimulation syndrome and hyperreactio luteinalis are indeed entities in continuum. Ultrasound Obstet Gynecol 2004:24:675-8.

18. Haimov-Kochman R. Fetal programming, the intrauterine origin of adult diseases. Harefuah 2005:144:97-101.

19. Haimov-Kochman R, Prus D, Zcharia E, Goldman-Wohl DS, Natanson-Yaron S, Greenfield C, Anteby   EY, Reich R, Orly J, Tzafriri A, Hurwitz A, Vlodavsky I, Yagel S. Spatiotemporal expression of heparanase during human  and rodent ovarian folliculogenesis. Biol Reprod 2005: 73(1):20-8

20. Anteby EY, Natanson-Yaron S, Greenfield C, Goldman-Wohl D, Haimov-Kochman R, Holzer H, Yagel S. Human Placental Hofbauer cells express sprouty Proteins: A Possible modulating mechanism of villous branching. Placenta 2005:26(6):476-83.

21. Revel A, Haimov-Kochman R, Porat  A, Lewin A, Simon A, Laufer N, Gino H, Meirow D. In vitro fertilization-intracytoplasmic sperm injection success rates with cryopreserved sperm from patients with malignant disease.  Fertil Steril 2005:84(1):118-22.

22. Haimov-Kochman R, Hochner-Celinkier D. Hot Flashes-Revisited: Alternative Therapeutic Options for Hot Flashes Management. What Does the Evidence Tell Us? Acta Obstet Gynecol Scand 2005: 84(10):972-9.

23. Haimov-Kochman R, Hochner-Celinkier D. Are there second thoughts about the results of the WHI study? (Accepted to publication in Acta Obstet Gynecol Scand)

24. Haimov-Kochman R, Ravhon A, Prus D, Finci-Yeheskel Z, Goldman-Wohl DS, Natanson-Yaron S, Greenfield C, Reich R, Yagel S, Hurwitz A.  Expression and regulation of Sprouty-2 in the granulosa lutein cells of the corpus luteum. Mol Hum Reprod 2005: 11(8):537-42. 

25. Haimov-Kochman R , Sciaky-Tamir Y , Hurwitz A . Reproduction Concepts and Practices in Ancient Egypt Mirrored by Modern Medicine. Eur J Obstet Gynecol Reprod Biol 2005:123(1):3-8.

26. Haimov-Kochman R, Fisher JS, Winn DV. Modification of the Standard Trizol-Based Technique Improves the Integrity of RNA Isolated from RNase-Rich Placental Tissue.  Clin Chem 2006:52(1):159-60.

27. Haimov-Kochman R, Barak-Glantz E, Leefsma M, Arbel R, Brzeziski A, Milwidsky A, Hochner-Celnikier D. Gradual Discontinuation of Hormone Therapy does not Prevent the Reappearance of Climacteric Symptoms. A Randomized Prospective Study. (Accepted to publication in Menopause).