Updated 1/1/2010
Attending cardiologist,
Heart Institute
Hadassah Medical Center
Jerusalem, Israel
E-mails: ronny@hadassah.org.il
ralcalai@genetics.med.harvard.edu
Personal Data
Date of birth: December 19, 1966
Place of birth: Jerusalem, Israel
Citizenship: Israeli
Military service: 1985-88 - Medical assistant in the IDF (paratroopers)
Marital status: Married, 3 children
MD license no: 29457 (1997)
Expert license no.: Internal medicine - 18885 (2001) Cardiology – 21102 (2004)
Education
1989-95: Hadassah School of Medicine, Hebrew University of Jerusalem, Israel
1992: B.Sc. – Medical Sciences, Hebrew University of Jerusalem
1996: MD degree - Hebrew University-Hadassah School of Medicine, Jerusalem. Medical thesis: “Acute Myeloid Leukemia, clinical and genetic aspects”. Thesis advisor: Prof. D. Ben-Yehuda.
1997: ECFMG certificate
2000: Passed both parts of the Israeli boards in Internal Medicine
2003: Passed both parts of the Israeli boards in Cardiology.
2003: Good Clinical Practice course, Hebrew University of Jerusalem
Postgraduate medical practice
1996-1997: Internship: Hadassah Medical Center, Jerusalem, Israel
1997-2001: Residency: Department of Internal medicine, Hadassah Hospital, Mt. Scopus, Jerusalem (completed – June 2001)
2001-2004: Fellowship: Cardiology, the heart institute, Hadassah Medical Center, Jerusalem
2004 – 2005: Attending cardiologist, heart institute, Hadassah Medical Center, Jerusalem
2005 – 2007: Research Fellow, Dept. of cardiovascular genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.
2007 – to date Attending cardiologist, heart institute, Hadassah Medical Center, Jerusalem
Academic position
2007 - Lecturer
Awards and honors
1997, Award for outstanding internship, Hebrew University, Hadassah School of Medicine
2002, Kellerman young investigator award. 49th Annual meeting of the Israeli Society of Cardiology, Tel-Aviv, Israel
2002, the Louis Chor Memorial Trust Prize
2003, Award for outstanding lecturer, Hebrew University, Hadassah School of Medicine
2003, Award by the Israeli Society for Prevention and Treatment of Atherosclerosis
2008, Matzner award for outstanding physician, Hebrew University, Hadassah School of Medicine
Grants
2002: Grant from the Eisenberg Foundation: Safety and efficacy of intra-vascular cooling device in in out of hospital cardiac arrest survivors. 20,000NIS
2005: Grant from the American Physician Fellowship. 5,000$
2006-2007: Grant from the Machiah Foundation/JCF Program. Development of conduction system abnormalities. 100,000$
2008: Grant from the chief scientist office, Ministry of health, Jerusalem. Mechanism of Lamp-2 Cardiomyopathy. 110,000$
Teaching Responsibilities
1997-2000: Lecturer for 4th and 6th year medical students in the Dept. of internal medicine, Hadassah University Hospital
2001-2005: Lecturer for 4th and 6th year medical students in the Dept. of Cardiology, Hadassah University Hospital
Course in intensive care for nurses, Hadassah University Hospital
Course in advanced cardiac life support (ACLS) for the medical staff at the Hadassah University Hospital
2005: Member in the national final exams boards in Cardiology and Internal Medicine
2007-2010: Teaching coordinator, 4th and 6th year medical students, Dept. of Cardiology, Hadassah University Hospital Course in advanced cardiac life support (ACLS) for the medical staff at the Hadassah University Hospital
Publications
Original articles:
1. R Alcalai, D Ben-Yehuda, I Ronen, O Paltiel. Ethnicity and prognosis in acute myeloid leukemia. Am J of Hematol 2003; 72(2):127-134.
2. R Alcalai, S Metzger, S Rozenheck, V Mainer, T Chajek-Shaul. A Recessive Mutation in Desmoplakin Causes Arrhythmogenic Right Ventricular Dysplasia, Skin Disorder and Woolly Hair. J Am Coll Cardiol 2003; 42(2):319-327.
3. D Elian , V Guetta , R Alcalai, C Lotan , A Segev . Early mobilization after diagnostic cardiac catheterization with the use of a hemostatic bandage containing thrombin. Cardiovasc Revasc Med. 2006;7(2):61-3.
4. G Landesberg , Y Berlatzky, M Bocher, R Alcalai, H Anner, T Ganon-Rozental, MH Luria, I Akopnik, C Weissman, M Mosseri. A clinical survival score predicts the likelihood to benefit from preoperative thallium scanning and coronary revascularization before major vascular surgery. Eur Heart J. 2007; 28(5):533-9.
5. R Alcalai, N Viola, M Mosseri ,R Beeri , D Leibowitz , C Lotan , D Gilon. The value of PCI in patients with symptomatic aortic stenosis and coronary artery disease. Am J Med, 2007;120(2):185.e7-13.
6. R Alcalai, D Planer, A Culhaoglu, A Osman, A Pollak , C Lotan. Acute coronary syndrome vs. non specific troponin elevation, clinical predictors and survival analysis. Arch Intern Med, 2007;167(3):276-81.
7. R Alcalai, L Song, M Arad, CM Wolf, O Toka, DA Conner, CI Berul, M Eldar, CE Seidman, JG Seidman. Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia. J Clin Invest. 2007;117(7):1814-23.
8. CM Wolf, L Wang, R Alcalai, A Pizard, PG Burgon, F Ahmad, MC Sherwood, DM Branco, H Wakimoto, GI Fishman, V See, CL Stewart, DA Connor, CI Berul, CE Seidman, JG Seidman. Lamin A/C Haploinsufficiency Causes Dilated Cardiomyopathy and Apoptosis-Triggered Cardiac Conduction System Disease. J Mol Cell Cardiol, 2008; 44:293–303.
Case Reports, Letters and Reviews
9. JM Reichman, R Alcalay, G Spectre. Haemophilus influenzae pyelonephritis in adults. Arch Intern Med 1999; 159 (12).
10. R Alcalai, G Spectre, M Burztyn. Smoking, cough and polyuria. Arch Intern Med 2002; 162 (2).
11. R Alcalai, C Lotan. Interventional Cardiology: From Balloon Angioplasty to Gene Therapy. Journal of Israel Heart Society 2003;13(2):32-36.
12. R Alcalai, D Planer, A Pollak, C Lotan. Nonspecific Troponin Elevation—Reply. Arch Intern Med 2007; 167:1907.
13. R Alcalai, JG Seidman, CE Seidman. Genetic Basis of Hypertrophic Cardiomyopathy: From Bench to the Clinics. J Cardiovasc Electrophysiol. 2008;19(1):104-10.
14. R Alcalai. Management of Patients with High Levels of Troponin, Hospitalized in Internal Wards. Israeli Journal of Medicine 2008; 10:45-48.
International Abstracts and presentations
1. Ora Paltiel, Ronny Alcalai,, Ilana Ronen, Dina Ben-Yehuda. Ethnicity as a prognostic factor in adults with acute myeloid leukemia. The American Society of Hematology, 43rd Annual meeting and exposition. Dec. 2001, Orlando, Florida. Blood supp. 2001
2. Ronny Alcalai, Shula Metsger, Shimon Rozenheck, Tova Chajek-Shaul. A Recessive Mutation in Desmoplakin Causes Arrhythmogenic Right Ventricular Dysplasia, Skin Disorder and Woolly Hair, Scientific Sessions of the American Heart Association, Nov. 2002, Chicago, Ill. USA. Circulation Supp. November 5, 2002
3. Ronny alcalai, Lei Song, Michael Arad, Cordula Wolf, Okan Toka, Christine E Seidman, Jon G Seidman. Intraluminal Calcium is depleted during stress and causes ventricular arrhythmia in a CPVT knock-in mouse model carrier of a mutation in the cardiac Calsequestrin. Gordon Research conference on cardiac regulatory mechanisms, July 2006, NH, USA.
4. Lei Song, Ronny Alcalai, Michael Arad, , Condula Wolf, Mikhail Bourgoun, David Conner, Jonathan Seidman, Christine Seidman. Calsequestrin mutation causes arrhythmia related to the intraluminal Ca2+ transient abnormality. Scientific Sessions of the American Heart Association, Nov. 2006, USA. Circulation 114 (18): 7-8 Suppl. , Oct 31, 2006
5. Hiroko Wakimoto, Ronny Alcalai, Michael Arad, Lei Song, Christine E Seidman, J G Seidman, Charles I Berul Prevention of Fatal Arrhythmia in a Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model Carrying Calsequestrin-2 Mutation Scientific Sessions of the American Heart Association, Nov. 2007, Orlando USA. Circulation 116 (16) 16 Suppl. Oct 16, 2007
6. Ronny Alcalai, Michael Arad, Libin Wang, Fredric depreux, Sinone Ward, Antonio Perez, Jonathan Seidman, Christine Seidman. Cardiac hypertrophy, conduction system abnormalities and autophagic vacuoles accumulation in Lamp2 knock-in mouse model. Idiopathic and Primary Cardiomyopathy in Children: Research Directions and Strategies Conference. Bethesda, MD. January 25-26, 2007.
7. Ronny Alcalai, Hiroko Wakimoto Michael Arad, Lei Song, Christine E Seidman, J G Seidman, Charles I Berul Prevention of Fatal Arrhythmia and calcium dysregulation in a Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model. Scientific Sessions of the American Heart Association, Nov. 2009, Orlando USA.
Publications on
PupMed