Treatment of Superficial Bladder Cancer with Intravesical Chemotherapy and Hyperthermia (SynergoR).

Superficial bladder cancer is usually treated by endoscopic, trans-urethral surgery. 

Using special optical instruments that can be inserted through the urethra, the tumors are removed by electrical resection.

However, in more than 50% of the cases new tumors may develop in the bladder, most of them within 2 years. About 20% of newly diagnosed superficial bladder tumors and 10-15% of recurrent tumors are highly malignant and they tend to invade the bladder wall. These tumors can not be cured by endoscopic surgery alone.

Such tumors can be managed successfully by the combination of trans-urethral surgery and intravesical instillation of chemotherapy, or immuotherapy with BCG. The combination therapy is used either to eradicate high grade, superficial tumors, or to prevent the recurrece of new tumors after the trans-urethral surgery.

During the last decade a new form of therapy has evolved. A combination of intravesical instillation of a cytotoxic drug and warming the bladder to 420C with microwave energy (the Synergo technique). This new technology is believed to achieve better results than intravesical chemotherapy alone. A clinical study that compares the efficacy of intravesical immunotherapy with BCG and  the Synergo-technique is currently done in multiple medical centers, including Hadassah.

Since early experience has shown good results, we offer the Synergo technique to every patient that had failed other intravesical treatments of superficial bladder cancer.

For more information call

Dr. Ofer Gofrit,   Tel: 02-6776877.