This new treatment was originated by M. Pistor M.D. in France in 1952. It is commonly practiced in France and in many other countries around the world, including Belgium, Columbia, Argentina, and throughout Europe.

Mesotherapy involves injecting small amounts of homeopathic medicine immediately under the surface of the skin to break down cellulite and to improve circulation. The addition of Vitamin C to the mixture encourages the tone and quality of the overlying skin. Mesotherapy stimulates the mesoderm, or middle layer of the skin, which in turn helps disburse cellulite.

The technique involves the injection of substances to stimulate the mesoderm for various biological purposes. For instance, if the mesoderm circulation is poor, a vasodilator is used; if excessive inflammation is present, an anti-inflammatory medication is used; or if inflammation/stimulation is needed, a fibroblast proliferating solution is injected. Conditions such as cellulite are due to lymph veno-lymphatic insufficiency, therefore a stimulator of venous and lymph flow is used. Cellulite and weight loss can be effectively managed with the use of mesotherapy.

Each treatment takes about ten minutes and is not painful. After the treatment, the patient can return to normal activities. The numerous therapeutic classifications used are essentially allopathic drugs that pharmacology has codified, mineral salts and trace elements; sometimes, homeopathic injectables are employed. Some of the drugs are: non-steroidal anti-inflammatory agents; beta-blockers; vasodilatators; anti-free radicals and vaccines. Corticoids are never used.

The treatment is long lasting and the results measurable. The scientific basis of mesotherapy is founded on intradermal pharmacokinetics theory:

- the superficial derma forms a cutaneous reservoir for injected molecules whose persistence is inversely proportional to the depth of the injection

- the low density molecules are diffused by the capillary bed to the systemic circulation
- the high density molecules are diffused by the lymphatic vessels

- all those products become concentrated in their target organs and tissues according to their own affinity, shunting the hepatic first passage

Note that the trans-dermal pathway of administering molecules is akin to the "patch" method and to ointments with systemic penetration. However, those forms can only introduce a restricted number of low-density molecules, because of the difficulty in penetrating the epidermal barrier. This obstacle is also resolved by our technique.

Mesotherapy is helpful in treating painful pathologies, osteoarthropathy, sport injuries, neurological problems, chronic infections, allergies and immunities, stomatology and aesthetic medicine. It is not recommended for patients with injection phobia or allergies to one of the active principles

The advantages of the treatment derive from the use of conventional drugs with well known pharmacology, small amounts, local injections and the possibility of treating fragile patients, such as the elderly. Overall, with a moderate amount of lifestyle change, mesotherapy can provide measurable improvement after few sessions.

To the site of the
Israel Society of Mesotherapy