1/1/2010

Ronny Alcalai - CURRICULUM VITAE

Personal Data

Name                          Ronny Alcalai

Address                       8 Harimon Street,

                                    Moza Ilit, Israel  90820

                                    Tel: 972-2-5337914

E-mail:                         ronny@hadassah.org.il

ralcalai@genetics.med.harvard.edu 

Date of birth                December 19, 1966

Place of birth               Jerusalem, Israel

Citizenship                  Israeli

Military service            1985-88 - Medical assistant in the IDF (paratroopers)

Marital status               Married, 3 children

MD license no.            29457 (1997)

Expert license no.       Internal medicine - 18885 (2001)                                                                                Cardiology – 21102 (2004)

Education

1989-95                        Hadassah School of Medicine, Hebrew University of Jerusalem, Israel              

1992                            B.Med.Sc. – Hebrew University of Jerusalem

1996                            MD degree - Hebrew University of Jerusalem

Medical thesis:  “Acute Myeloid Leukemia, clinical and genetic aspects”. Thesis advisor: Prof. D. Ben-Yehuda.

1997                                                          ECFMG certificate

2000                            Passed both parts of the Israeli boards in Internal Medicine

2003                            Passed both parts of the Israeli boards in Cardiology.

2003                            Good Clinical Practice course, Hebrew University of Jerusalem

Postgraduate medical practice

1996-1997                   Internship: Hadassah Medical Center, Jerusalem, Israel

1997-2001                   Residency: Department of Internal medicine, Hadassah Hospital, Mt. Scopus, Jerusalem (completed – June 2001)

2001-2004                   Fellowship: Cardiology, the heart institute, Hadassah Medical Center, Jerusalem

2004 – 2005                Attending cardiologist, heart institute, Hadassah Medical Center, Jerusalem

2005 - 2007                 Research Fellow, Dept. of cardiovascular genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.

2007 – to date             Attending cardiologist, heart institute, Hadassah Medical Center, Jerusalem

Academic position

2007 - Lecturer

Awards and honors

1.      1997, Award for outstanding internship, Hebrew University, Hadassah School of Medicine

2. 2002, Kellerman young investigator award. 49^th Annual meeting of the

            Israeli Society of Cardiology, Tel-Aviv, Israel

1. 2002, the Louis Chor Memorial Trust Prize
2. 2003, Award for outstanding lecturer, Hebrew University, Hadassah School of Medicine
3. 2003, Award by the Israeli Society for Prevention and Treatment of Atherosclerosis
4. 2008, Matzner award for outstanding physician, Hebrew University, Hadassah School of Medicine

Grants

2002                                Grant from the Eisenberg Foundation: Safety and efficacy of intra-vascular cooling device in in out of hospital cardiac arrest survivors.  20,000NIS

2005                Grant from the American Physician Fellowship. 5,000$       

2006-2007      Grant from the Machiah Foundation/JCF Program. Development of conduction system abnormalities. 100,000$

2008                Grant from the chief scientist office, Ministry of health, Jerusalem. Mechanism of Lamp-2 Cardiomyopathy. 110,000$

Teaching Responsibilities

1997-2000              Lecturer for 4^th and 6^th year medical students in the Dept. of internal medicine, Hadassah University Hospital

2001-2005       Lecturer for 4^th and 6^th year medical students in the Dept. of Cardiology, Hadassah University Hospital

Course in intensive care for nurses, Hadassah University Hospital

Course in advanced cardiac life support (ACLS) for the medical staff at the Hadassah University Hospital

2005                                Member in the national final exams boards in Cardiology and Internal Medicine

2007-2010             Teaching coordinator, 4^th and 6^th year medical students, Dept. of  Cardiology, Hadassah University Hospital

                       Course in advanced cardiac life support (ACLS) for the medical staff at the Hadassah University Hospital

Publications

Original articles:

1.      R Alcalai, D Ben-Yehuda, I Ronen, O Paltiel. Ethnicity and prognosis in acute myeloid leukemia. Am J of Hematol 2003; 72(2):127-134.

2.      R Alcalai, S Metzger, S Rozenheck, V Mainer, T Chajek-Shaul. A Recessive Mutation in Desmoplakin Causes Arrhythmogenic Right Ventricular Dysplasia, Skin Disorder and Woolly Hair. J Am Coll Cardiol 2003; 42(2):319-327. 

3.      D Elian , V Guetta , R Alcalai, C Lotan , A Segev . Early mobilization after diagnostic cardiac catheterization with the use of a hemostatic bandage containing thrombin. Cardiovasc Revasc Med. 2006;7(2):61-3.

4.         G Landesberg , Y Berlatzky, M Bocher, R Alcalai, H Anner, T Ganon-Rozental, MH Luria, I Akopnik, C Weissman, M Mosseri. A clinical survival score predicts the likelihood to benefit from preoperative thallium scanning and coronary revascularization before major vascular surgery. Eur Heart J. 2007; 28(5):533-9.

5.      R Alcalai, N Viola, M Mosseri ,R Beeri , D Leibowitz , C Lotan ,   D Gilon. The value of PCI in patients with symptomatic aortic stenosis and coronary artery disease. Am J Med, 2007;120(2):185.e7-13.

6.      R Alcalai, D Planer, A Culhaoglu, A Osman,  A Pollak , C Lotan. Acute coronary syndrome vs. non specific troponin elevation, clinical predictors and survival analysis. Arch Intern Med, 2007;167(3):276-81.

7.      R Alcalai, L Song, M Arad, CM Wolf, O Toka, DA Conner, CI Berul, M Eldar, CE Seidman, JG Seidman. Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia. J Clin Invest. 2007;117(7):1814-23.

8.      CM Wolf, L Wang, R Alcalai, A Pizard, PG Burgon, F Ahmad, MC Sherwood, DM Branco, H Wakimoto, GI Fishman, V See, CL Stewart, DA Connor, CI Berul, CE Seidman, JG Seidman. Lamin A/C Haploinsufficiency Causes Dilated Cardiomyopathy and Apoptosis-Triggered Cardiac Conduction System Disease. J Mol Cell Cardiol, 2008; 44:293–303.

Case reports, letters and reviews:

9.      JM Reichman, R Alcalay, G Spectre. Haemophilus influenzae pyelonephritis in adults. Arch Intern Med 1999; 159 (12).

10.  R Alcalai, G Spectre, M Burztyn. Smoking, cough and polyuria. Arch Intern Med 2002; 162 (2).

11.  R Alcalai, C Lotan. Interventional Cardiology: From Balloon Angioplasty to Gene Therapy. Journal of Israel Heart Society 2003;13(2):32-36.

12.  R Alcalai,  D Planer, A Pollak, C Lotan. Nonspecific Troponin Elevation—Reply
Arch Intern Med 2007; 167:1907.

13.   R Alcalai, JG Seidman, CE Seidman. Genetic Basis of Hypertrophic Cardiomyopathy: From Bench to the Clinics. J Cardiovasc Electrophysiol.  2008;19(1):104-10.

14.   R Alcalai. Management of Patients with High Levels of Troponin, Hospitalized in Internal Wards. Israeli Journal of Medicine 2008; 10:45-48.

International Abstracts and presentations

1.        Ora Paltiel, Ronny Alcalai,, Ilana Ronen, Dina Ben-Yehuda. Ethnicity as a prognostic factor in adults with acute myeloid leukemia. The American Society of Hematology, 43^rd Annual meeting and exposition. Dec. 2001, Orlando, Florida. Blood supp. 2001

2.       Ronny Alcalai, Shula Metsger, Shimon Rozenheck, Tova Chajek-Shaul. A Recessive Mutation in Desmoplakin Causes Arrhythmogenic Right Ventricular Dysplasia, Skin Disorder and Woolly Hair, Scientific Sessions of the American Heart Association, Nov. 2002, Chicago, Ill. USA. Circulation Supp. November 5, 2002

3.      Ronny alcalai, Lei Song, Michael Arad, Cordula Wolf, Okan Toka, Christine E Seidman, Jon G Seidman. Intraluminal Calcium is depleted during stress and causes ventricular arrhythmia in a CPVT knock-in mouse model carrier of a mutation in the cardiac Calsequestrin. Gordon Research conference on cardiac regulatory mechanisms, July 2006, NH, USA.

4.       Lei Song, Ronny Alcalai, Michael Arad, , Condula Wolf, Mikhail Bourgoun, David Conner, Jonathan Seidman, Christine Seidman. Calsequestrin mutation causes arrhythmia related to the intraluminal Ca²⁺ transient abnormality. Scientific Sessions of the American Heart Association, Nov. 2006, USA. Circulation 114 (18): 7-8 Suppl. , Oct 31, 2006

5.       Hiroko Wakimoto, Ronny Alcalai, Michael Arad, Lei Song, Christine E Seidman, J G Seidman, Charles I Berul Prevention of Fatal Arrhythmia in a Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model Carrying Calsequestrin-2 Mutation Scientific Sessions of the American Heart Association, Nov. 2007, Orlando USA. Circulation 116 (16) 16 Suppl. Oct 16, 2007

6.       Ronny Alcalai, Michael Arad, Libin Wang, Fredric depreux, Sinone Ward, Antonio Perez, Jonathan Seidman, Christine Seidman. Cardiac hypertrophy, conduction system abnormalities and autophagic vacuoles accumulation in Lamp2 knock-in mouse model. Idiopathic and Primary Cardiomyopathy in Children: Research Directions and Strategies Conference. Bethesda, MD. January 25-26, 2007.

7.        Ronny Alcalai, Hiroko Wakimoto Michael Arad, Lei Song, Christine E Seidman, J G Seidman, Charles I Berul Prevention of Fatal Arrhythmia and calcium dysregulation in a Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model. Scientific Sessions of the American Heart Association, Nov. 2009, Orlando USA. 

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