Development of hardware and computer techniques for the measurement of lung function in infants.

      Acoustic analysis of breath sounds for the detection and quantification of wheezing in infants and young children.

      Studies of bronchial reactivity in infants, children and adults with asthma and other types of chronic lung disease.

      Studies of nitric oxide levels in normal adults and children and in patients with lung disease.

      Development of diagnostic techniques for detecting gastroesophageal reflux and aspiration in animal models and in young children.

      Lung function methodology

      Mechanisms of lung fibrosis

      Positron emission tomography (PET) scan in lung cancer

      Screening and early detection of lung cancer

      Genetic predisposition for lung cancer

      Pulmonary hypertension including genetic screening

      Chemokines and Asthma

      Murine model of post-transplant bronchiolitis obliterans

      Predicting diagnosis and disease activity of interstitial lung disease with the aid of positron emission tomography (PET) scan.